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Pfizer efficacy down to 42% while FDA standard for safe/effective/approval is 50%

Posted on 8/11/21 at 12:40 am
Posted by Shaft Williams
Central City, LA
Member since Jul 2010
9450 posts
Posted on 8/11/21 at 12:40 am


LINK
This post was edited on 8/11/21 at 12:41 am
Posted by John McClane
Member since Apr 2010
36706 posts
Posted on 8/11/21 at 1:08 am to
Facts schmacts
Posted by BigJim
Baton Rouge
Member since Jan 2010
14511 posts
Posted on 8/11/21 at 1:12 am to
Against the Delta variety.

If confirmed, they will not get full approval. Moderna fixing to eat.
Posted by AUstar
Member since Dec 2012
17056 posts
Posted on 8/11/21 at 1:26 am to
Jack Posobiec gives no context, of course. So I dug up the actual study. Here is what it says:

quote:

Both vaccines were highly effective during this study period against SARS-CoV-2 infection (mRNA-1273: 86%, 95%CI: 81-90.6%; BNT162b2: 76%, 95%CI: 69-81%) and COVID-19 associated hospitalization (mRNA-1273: 91.6%, 95% CI: 81-97%; BNT162b2: 85%, 95% CI:73-93%). However, in July, the effectiveness against infection was considerably lower for mRNA-1273 (76%, 95% CI: 58-87%) with an even more pronounced reduction in effectiveness for BNT162b2 (42%, 95% CI: 13-62%).


In other words, Moderna still going strong at 76%. Pfizer seems to be down to 42% against Delta insofar as protecting against infection.

However, they also said this:

quote:

Our observational study highlights that while both mRNA COVID-19 vaccines strongly protect against infection and severe disease, further evaluation of mechanisms underlying differences in their effectiveness such as dosing regimens and vaccine composition are warranted.


As you can see above, Moderna was 91% effective at preventing hospitalization and Pfizer was at 85%. So let's not pretend it's the end of the world. Yes, the efficacy has decreased with Delta, but the beauty of mRNA is they can quickly tweak it for new variants (in like days). They don't have to grow or culture the virus to do this.
Posted by David_DJS
Member since Aug 2005
17975 posts
Posted on 8/11/21 at 1:30 am to
quote:

Yes, the efficacy has decreased with Delta, but the beauty of mRNA is they can quickly tweak it for new variants (in like days). They don't have to grow or culture the virus to do this.

How do they compare to natural immunity?
Posted by FooManChoo
Member since Dec 2012
41722 posts
Posted on 8/11/21 at 1:30 am to
Does that mean the vax passports are no longer valid for Pfizer jabs?
Posted by sawtooth
Baton Rouge
Member since Jul 2017
3588 posts
Posted on 8/11/21 at 4:55 am to
Don’t care. I am not vaccinated. I feel fine.
Posted by Cuz413
Member since Nov 2007
7361 posts
Posted on 8/11/21 at 5:11 am to
Pfizer bux in the right hands= Breaking News--new standard for vaccine efficacy for Covid now at 42%
Posted by Armymann50
Playing with my
Member since Sep 2011
17135 posts
Posted on 8/11/21 at 5:34 am to
quote:

FDA standard for safe
me still not getting the jab
Posted by geauxturbo
Baton Rouge
Member since Aug 2007
4171 posts
Posted on 8/11/21 at 5:44 am to
quote:

As you can see above, Moderna was 91% effective at preventing hospitalization 


Curious how they determine if it is the vax that is effective at prevetnting hospitalization.
Posted by jimmy the leg
Member since Aug 2007
34321 posts
Posted on 8/11/21 at 5:44 am to
quote:

Yes, the efficacy has decreased with Delta, but the beauty of mRNA is they can quickly tweak it for new variants (in like days).


So boosters for life. Beauty is in the eye of the holder I suppose.

Tell me more about natural immunity. That is, IF you can actually find any info that isn’t either dismissed (like Dr. Catherine O’Neal did as JBE’s mouthpiece), limited in scope, or....seemingly buried.
This post was edited on 8/11/21 at 5:48 am
Posted by jonnyanony
Member since Nov 2020
10018 posts
Posted on 8/11/21 at 5:47 am to
quote:

How do they compare to natural immunity?


If you had a non Delta variant infection they're effectively the same.
Posted by theunknownknight
Baton Rouge
Member since Sep 2005
57429 posts
Posted on 8/11/21 at 5:47 am to
The relative risk reduction is what they are reporting and that doesn’t have any real world impact when the actual risk is through the floor in the first place.
This post was edited on 8/11/21 at 8:11 am
Posted by jimmy the leg
Member since Aug 2007
34321 posts
Posted on 8/11/21 at 5:48 am to
quote:

If you had a non Delta variant infection they're effectively the same.


Based on what? Links?


ETA

There is zip about natural immunity being in the 42% to 87% range concerning the Delta variant. There are studies that show it works at a higher percentage (90%+), but nothing in the range that you suggested (“effectively the same”).
This post was edited on 8/11/21 at 5:57 am
Posted by Revelator
Member since Nov 2008
58130 posts
Posted on 8/11/21 at 5:59 am to
Where is he getting the 42% efficacy claim? I’m not saying he’s wrong, but he doesn’t site any studies but simply makes a claim.
Posted by Jack Daniel
In the bottle
Member since Feb 2013
25527 posts
Posted on 8/11/21 at 6:26 am to
So a new shot for each “variant”?
Posted by shell01
Marianna, FL
Member since Jul 2014
793 posts
Posted on 8/11/21 at 6:28 am to
quote:

Tell me more about natural immunity


Here's a summary of what we know about naturally acquired immunity:
LINK

Cliffnotes... durability of immunity conferred by prior infection is variable, and less protective against delta variant (especially if prior infection was more than 6 months ago.) Also, vaccinated after infection are half as likely to be reinfected (see the Kentucky study.)
Posted by diat150
Louisiana
Member since Jun 2005
43638 posts
Posted on 8/11/21 at 6:29 am to
quote:

you can see above, Moderna was 91% effective at preventing hospitalization and Pfizer was at 85%.


What is hospitalization % of unvaccinated ?
Posted by OceanMan
Member since Mar 2010
20032 posts
Posted on 8/11/21 at 6:30 am to
quote:

Yes, the efficacy has decreased with Delta, but the beauty of mRNA is they can quickly tweak it for new variants (in like days).


Is that the game plan? Asking people to get jabbed for each variant?

If people oppose getting one or two to talk it’s going to get ugly if it’s multiple per year.
Posted by jimmy the leg
Member since Aug 2007
34321 posts
Posted on 8/11/21 at 6:34 am to
The Kentucky study was bullshite.

How can you push this drivel and act like you have any semblance of credibility.

The dumb bitch writing your article is citing a study with FIVE people.

frick off with this garbage.

Here is the CDC link to that “study.”

frick off
This post was edited on 8/11/21 at 6:41 am
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