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re: Gov. issues stay-at-home order for South Florida -- through mid-May! - shell01 on 3/30/20 at 12:47 pm
[quote]Heavily populated [/quote] Fixed it for you. 58% of Florida's population resides in those 4 counties. Also where the vast majority of cases are so far. A much more tempered move than a statewide order. ...Jump to Post - View Topic - Replies (0)
re: "I am still working, working from home" check in thread - shell01 on 3/30/20 at 10:12 am
I oversee clinical research trials. Very busy at the moment... Most of my teams are home based year-round, the biggest impact for most has been having additional people at home (children, spouses, etc.) ...Jump to Post - View Topic - Replies (0)
re: Shouldn't the news of FDA authorizing Hydroxychloroquine be major? - shell01 on 3/30/20 at 8:53 am
Thank you Hopeful Doc. Seems so many here still have trouble with reading comprehension. Don't worry, you'll get dozens of downvotes for not drinking the kool-aid...Jump to Post - View Topic - Replies (0)
re: FDA issues emergency authorization of 2 anti-malaria drugs for coronavirus treatment - shell01 on 3/30/20 at 6:27 am
This is an emergency use authorization, not an approval. All this does is allow the donation to, and distribution from the strategic national supply. Sanofi and Novartis have / are providing doses of chloroquine and HCQ to the government, and the government is providing a mechanism for health ...Jump to Post - View Topic - Replies (0)
re: Novartis CEO says Malaria drug is biggest hope against coronavirus - shell01 on 3/29/20 at 4:24 pm
[quote]is the company's biggest hope [/quote] The company's biggest hope, not the world's best. Devil is in the details ;) Last I checked there were almost 100 novel agents being tested against COVID-19. Let's all hope there are a few winners in the bunch. ...Jump to Post - View Topic - Replies (0)
re: Clinical trials: Don’t be part of clinical trial unless you are willing to die for science - shell01 on 3/29/20 at 12:19 pm
[quote]How much money do you get to be in a clinical trial?[/quote] Healthy people volunteering for a phase 1 trial receive compensation for their troubles. They have nothing to gain and everything to lose. Patients with the disease under study do NOT receive payment to take part. That would ...Jump to Post - View Topic - Replies (1)
re: Where are we with Hydroxychloroquine? - shell01 on 3/29/20 at 10:02 am
[quote]Strongly disagree. It’s not just mild cases where the combo is making a difference. In fact, most cases where this is getting applied is the extreme “nothing left to lose” cases. [/quote] In reported studies? Wrong. Anecdotally in practice, possibly. Looking forward to seeing the dat...Jump to Post - View Topic - Replies (0)
re: Where are we with Hydroxychloroquine? - shell01 on 3/29/20 at 9:59 am
[quote]Would 1100 be an acceptable study?[/quote] It's not only about the n but the study design. Who is being treated? What is being measured? Is there a control group? But yes, obviously 1100 is more compelling than 20. ...Jump to Post - View Topic - Replies (0)
re: Where are we with Hydroxychloroquine? - shell01 on 3/29/20 at 8:48 am
Why didn't you quote the Conclusion of the review article you posted? [quote]Conclusions: There is rationale, pre-clinical evidence of effectiveness and evidence of safety from long-time clinical use for other indications to justify clinical research on chloroquine in patients with COVID-19. Howe...Jump to Post - View Topic - Replies (3)
re: Where are we with Hydroxychloroquine? - shell01 on 3/28/20 at 7:46 pm
[quote]There is also the australian study that came right after the french study.[/quote] Link? David Paterson from Queensland is running a trial now, but only reference to results I can find is in-vitro testing not in patients. Listen, I hope this stuff works, and look forward to seeing re...Jump to Post - View Topic - Replies (1)
re: Where are we with Hydroxychloroquine? - shell01 on 3/28/20 at 7:07 pm
[quote]There are multiple studies that show >90% survival using the drug.[/quote] Let's look at some of the studies reported to date. If you have others in addition to the below I would love a link to the publication to read. 1) [link=(https://www.sciencedirect.com/science/article/pii/S09248...Jump to Post - View Topic - Replies (2)
re: New French Study on Hydroxychloroquine/Azithromycin - IT WORKS!! - shell01 on 3/28/20 at 2:17 pm
[quote]The concern was he didn’t do a double-blind study with a placebo. That’s the standard our medical community is used to. under normal conditions. this is a much more urgent situation[/quote] Urgent or not, without a double blind placebo control, or a matched cohort at a non-participating h...Jump to Post - View Topic - Replies (0)
re: FYI on the use of ventilators and how stupid everyone is being - shell01 on 3/19/20 at 1:04 pm
[quote]He must have hyperbaric chambers and ventilators confused[/quote] Or maybe he's thinking ECMO. I run critical care research studies for a living, for the last 20 yrs or so. US ICUs have 1 vent per bed. Second tier ICU care countries may have slightly less but still no less than a ventila...Jump to Post - View Topic - Replies (0)
re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC*** - shell01 on 3/14/20 at 3:58 pm
Difference between severe and critical/ICU for ARDS is oxygenation requirements. Non-invasive vs invasive (intubated) ventilation required to keep blood oxygenation, PF ratios etc compatible with life....
Posted on O-T LoungeJump to Post - View Topic - Replies (0)
re: Who all is taking this virus seriously and who’s not? - shell01 on 3/13/20 at 9:16 pm
I'm taking it seriously because we have a window into what it may look like of we do not. I work in critical care medical research. For the last almost 20 years I've worked with the doctors who are and will be treating the most severe of the cases. [b]THEY[/b] are concerned, that makes me conc...Jump to Post - View Topic - Replies (0)
re: So baws how many we got on here that could work from Home fulltime?? - shell01 on 3/12/20 at 7:37 am
Not a baw but I've worked 100% remote for the last 7 years. Vast majority of our US employees are home based with varying amount of travel required depending on role. ...
Posted on O-T LoungeJump to Post - View Topic - Replies (1)
re: $12,000 Reward for Information Regarding the Whereabouts of an Ivory Billed Woodpecker - shell01 on 3/1/20 at 2:55 pm
[quote]Huge bird, mostly black with a red head.[/quote] The only woodpecker with an actual red head is the (wait for it), red-headed woodpecker. Beautiful, striking birds but they are not ridiculously big. Pileated woodpeckers are very large birds, mostly black, but only a crown of red (and a...
Posted on Outdoor BoardJump to Post - View Topic - Replies (1)
re: $12,000 Reward for Information Regarding the Whereabouts of an Ivory Billed Woodpecker - shell01 on 3/1/20 at 2:50 pm
[quote]This sounds crazy, but last year, I saw two big arse wood peckers in my back yard. They looked almost prehistoric.[/quote] Pileated Woodpeckers They are very large, very distinctive both visually and sound (their calls and drums.) And the closest thing to IBWO we have left in the US. ...
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