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re: Pfizer efficacy down to 42% while FDA standard for safe/effective/approval is 50%

Posted on 8/11/21 at 3:40 pm to
Posted by WeeWee
Member since Aug 2012
40242 posts
Posted on 8/11/21 at 3:40 pm to
quote:

How do they compare to natural immunity?


There is no difference
Posted by David_DJS
Member since Aug 2005
18174 posts
Posted on 8/11/21 at 3:48 pm to
quote:

You mean the natural immunity that has the hospitals full of a majority non vaccinated? So that natural immunity?

I don't think you know what natural immunity is.
Posted by David_DJS
Member since Aug 2005
18174 posts
Posted on 8/11/21 at 3:49 pm to
quote:

If you had a non Delta variant infection they're effectively the same.

Thanks. I thought as much, though read something on these boards a few weeks ago that suggested natural immunity was actually a little more robust -v- variants because of the specificity of the vaccines. "Specificity" may not be the right word to use there, but you know what I mean.
Posted by bluedragon
Birmingham
Member since May 2020
6936 posts
Posted on 8/11/21 at 3:58 pm to
he efficacy of the Covid-19 vaccine developed by Pfizer and BioNTech fell from 96% to 84% over six months, according to data released Wednesday, a decline that could fuel Pfizer’s case that a third dose will eventually be required.

The data, released in a preprint that has not been reviewed by outside scientists, suggest the vaccine was 91% effective overall at preventing Covid-19 over the course of six months.

In the ongoing study, which enrolled more than 44,000 volunteers, the vaccine’s efficacy in preventing any Covid-19 infection that causes even minor symptoms appeared to decline by an average of 6% every two months after administration. It peaked at more than 96% within two months of vaccination and slipped to 84% after six months.

In the OP's opinion five is more than enough to run a study. In this study there was one SEVERE infection overall ....One in 44,000.....Looks like the OP used a YOHOO Journal report ....you guys know YoHoo, their Journalists are only old enough to buy YoHoo Chocolate drinks in the soda aisle at Publix.

Who the hell cares ....If you don't want the shot. Don't take the shot. Just don't waste anyone's time bitching when you catch something.
Posted by omegaman66
greenwell springs
Member since Oct 2007
22797 posts
Posted on 8/11/21 at 3:59 pm to
quote:

Pfizer efficacy down to 42%


So well below 42%.
Posted by jimmy the leg
Member since Aug 2007
34962 posts
Posted on 8/11/21 at 9:11 pm to
That’s a great study you chose to link.

quote:

The findings in this report are subject to at least five limitations. First, reinfection was not confirmed through whole genome sequencing, which would be necessary to definitively prove that the reinfection was caused from a distinct virus relative to the first infection. Although in some cases the repeat positive test could be indicative of prolonged viral shedding or failure to clear the initial viral infection (9), given the time between initial and subsequent positive molecular tests among participants in this study, reinfection is the most likely explanation. Second, persons who have been vaccinated are possibly less likely to get tested. Therefore, the association of reinfection and lack of vaccination might be overestimated. Third, vaccine doses administered at federal or out-of-state sites are not typically entered in KYIR, so vaccination data are possibly missing for some persons in these analyses. In addition, inconsistencies in name and date of birth between KYIR and NEDSS might limit ability to match the two databases. Because case investigations include questions regarding vaccination, and KYIR might be updated during the case investigation process, vaccination data might be more likely to be missing for controls. Thus, the OR might be even more favorable for vaccination. Fourth, although case-patients and controls were matched based on age, sex, and date of initial infection, other unknown confounders might be present. Finally, this is a retrospective study design using data from a single state during a 2-month period; therefore, these findings cannot be used to infer causation. Additional prospective studies with larger populations are warranted to support these findings.
Posted by Gifman
Member since Jan 2021
9809 posts
Posted on 8/11/21 at 9:14 pm to
42% of the time it works every time

Posted by the808bass
The Lou
Member since Oct 2012
111798 posts
Posted on 8/11/21 at 9:25 pm to
quote:

246 confirmed reinfections, compared to 492 case-matched residents.


How many of those were false positives? In one month in Kentucky? I’d guess somewhere around 246.
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