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re: Study: people return to baseline weight within 1.5 years of stopping GLP-1s

Posted on 3/5/26 at 11:07 pm to
Posted by soccerfüt
Location: A Series of Tubes
Member since May 2013
74850 posts
Posted on 3/5/26 at 11:07 pm to
Double post, sorry
This post was edited on 3/5/26 at 11:10 pm
Posted by soccerfüt
Location: A Series of Tubes
Member since May 2013
74850 posts
Posted on 3/5/26 at 11:07 pm to
TRIPLE post, sorry X 3!
This post was edited on 3/5/26 at 11:10 pm
Posted by TigerFlask
Colorado
Member since Oct 2004
321 posts
Posted on 3/6/26 at 12:29 am to
You are gay
Posted by LSUtoBOOT
Member since Aug 2012
20393 posts
Posted on 3/6/26 at 4:53 am to
quote:

Its why they stay on it

Treating symptoms is never permanent, the root cause must be corrected.
Posted by Loup
Ferriday
Member since Apr 2019
16970 posts
Posted on 3/6/26 at 6:37 am to
quote:

use of these drugs without a more comprehensive approach to weight management


no sh*t. if you go back to the same old habits that made you fat to begin with you're going to get fat again. If you develop good habits and discipline while on it and keep that up you'll probably keep the weight off when stopping.
Posted by ChatGPT of LA
Member since Mar 2023
6294 posts
Posted on 3/6/26 at 6:51 am to
Problem isn't the glp, its the fat fricks not changing their foods.

Its ALL about foods your fat slows. Its so fricking easy
Posted by Crow Pie
Neuro ICU - Tulane Med Center
Member since Feb 2010
27775 posts
Posted on 3/6/26 at 7:11 am to
quote:

I never understand why this fact is seen as a dunk against GLP 1s??
Healthy people subsidizing another persons unhealthy lifestyle?

Maybe because its very expensive and all the non lazy healthy people get mad when their insurance premiums are further exploding (RX is 34% of our company medical spend) because these people cant stop going to Popeyes for 3 piece spicy snack in between meals.

Posted by LSUfan20005
Member since Sep 2012
9224 posts
Posted on 3/6/26 at 7:12 am to
quote:

Once the leptin/ghrelin/serotonin mechanism gets messed up, it's just really, really difficult to get it to re-set to a new baseline.


Spot the frick on.

This is why it’s truly best to embrace a slow weight loss with sustainable lifestyle changes balancing results with satisfaction for adherence. Once a goal weight is achieved, ever so slowly return to maintenance to build a new set point.
Posted by Turnblad85
Member since Sep 2022
5541 posts
Posted on 3/6/26 at 7:16 am to
quote:

The key is not wanting to eat garbage



Yeah but have you tried peanut butter?

Get yourself a jar of peanut butter and a spoon and you got a goddman meal.
Posted by cgrand
HAMMOND
Member since Oct 2009
48924 posts
Posted on 3/6/26 at 7:19 am to
you will not exceed me in fondness for peanut butter. A peanut butter and banana smoothie is generally my breakfast
Posted by Turnblad85
Member since Sep 2022
5541 posts
Posted on 3/6/26 at 7:23 am to
I'm trying to make myself like the "natural" PB but man, creamy Jiff is something special.
Posted by ruzil
WNC
Member since Feb 2012
18378 posts
Posted on 3/6/26 at 7:34 am to
quote:

People with blood pressure issues get high blood pressure when they stop taking statins.


Really, tell me more.
Posted by Lsupimp
Ersatz Amerika-97.6% phony & fake
Member since Nov 2003
86170 posts
Posted on 3/6/26 at 7:54 am to
There will likely be a “ maintenance “ pill. Imagine the trillions in obesity- related health costs saved and all the people struggling with weight having relief. That’s really going to piss the OT off. Nothing pleases the OT quite like the suffering of fatties.
Posted by The Torch
DFW The Dub
Member since Aug 2014
29594 posts
Posted on 3/6/26 at 7:58 am to
BC/BS of Texas stopped covering these as of Jan 2026.

Mine went from $27.00 for three months to $3,900.00 which I'm not paying.

I've been hungry as hell ever since I stopped but have maintained my weight.

-73 lbs
Posted by i am dan
NC
Member since Aug 2011
31669 posts
Posted on 3/6/26 at 8:00 am to
Just another drug for lazy people to cover up symptoms rather than fixing their actual problem.
Posted by southpawcock
Member since Oct 2015
17729 posts
Posted on 3/6/26 at 8:01 am to
Whoever invented this shite is a financial genius.
Posted by theCrusher
Slidell
Member since Nov 2007
1740 posts
Posted on 3/6/26 at 8:02 am to
I know a number of people taking GLP-1s and they've all lost a significant amount of weight.

They also do the following just in smaller amounts.
1. Drink alcohol
2. Eat fried food
3. Eat carbs
4. Eat sweets
5. Eat little protein

They don't
1. Resistance train
2. Do any cardio
3. Don't make any attempt to move. Like walk every day.

They haven't changed any of the habits that made them fat. When they get off the GLP-1s I expect the hunger will return and they'll get fat again.
Posted by BigPapiDoesItAgain
Amérique du Nord
Member since Nov 2009
3473 posts
Posted on 3/6/26 at 8:09 am to
I look at it through the lens of a chronic disease. Definitely part of what I use to help people improve their metabolic health and (almost always) feel better about themselves. I've seen what an impact these drugs have on people from a biochemical standpoint that are just a wreck metabolically. I hope they continue to further and fine tune drugs in this class and drive the price down so they are more widely accessible. Also requires responsible administration and monitoring on the physician side and not just writing it, escalating the dose and forgetting about it. That's where you see people with side effects and poor use cases.
Posted by JDPndahizzy
JDP
Member since Nov 2013
6963 posts
Posted on 3/6/26 at 8:11 am to
quote:

Diabetics develop Diabetic Ketoacidosis when they stop taking insulin.

Not to be confused with Lactic Acidosis which killed Private Santiago.
Posted by Split2874
Mandeville
Member since Jul 2012
3520 posts
Posted on 3/6/26 at 8:13 am to
I used one for about a month, I could not stand the way it made me feel so I stopped, I lost 10lbs, but the bigger win was showing I could eat a lot less than I was before the drug. After I quit, I have changed my eating habits and eat a lot less than before.

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