re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***

Oxford vaccine triggers antibody and T cell response LINK

Seems like "United States" covers the most important part of the graph.

Is this owned by Gilead? Does it cost thousands of dollars per treatment?

If not, I doubt it gets much traction here. Ha.

Situation may be starting to improve in SC. Note, there has been no rollback of openings except that bars have to stop serving at 11pm and the masks mandates.

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So how did five nurses who worked the covid unit not get it where I do consulting and only 1 did?

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Same reason only 20% on the Diamond Princess got it?

SARS-CoV-2-specific T cell immunity in cases of COVID-19 and SARS, and uninfected controls

First a note:

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This is an unedited manuscript that has been accepted for publication. Nature Research are providing this early version of the manuscript as a service to our authors and readers. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers apply.

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Abstract (interesting part):

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Memory T cells induced by previous pathogens can shape the susceptibility to, and clinical severity of, subsequent infections1. Little is known about the presence of pre-existing memory T cells in humans with the potential to recognize SARS-CoV-2. Here, we first studied T cell responses to structural (nucleocapsid protein, NP) and non-structural (NSP-7 and NSP13 of ORF1) regions of SARS-CoV-2 in COVID-19 convalescents (n=36). In all of them we demonstrated the presence of CD4 and CD8 T cells recognizing multiple regions of the NP protein. We then showed that SARS-recovered patients (n=23) still possess long-lasting memory T cells reactive to SARS-NP 17 years after the 2003 outbreak, which displayed robust cross-reactivity to SARS-CoV-2 NP.

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Not much there but hopefully we'll see a full article peer-reviewed relatively soon.

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Same reason only 20% on the Diamond Princess got it?

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Will be interesting to see if they will ever be able to understand if certain groups already had immunity based on previous vaccines and/or exposure to other viruses. There is already a theory based on the timing of widespread MMR vaccination that would explain why the elderly are being hit so hard.

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There is already a theory based on the timing of widespread MMR vaccination that would explain why the elderly are being hit so hard.

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This sounds like nonsense, at least from your brief description.

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It's very correlative, but it is an idea out there. Folks from Tulane and LSU Health actually had a paper published concerning potentially using MMR vaccines as a cheap stop-gap for poor nations or something.

Think there may have been European research out there on the topic a while back too. Looked at age cohorts affected and a country's MMR vaccine policy.

Belgium was late to the requiring MMR vaccinations party, and they've had bad results in more age groups, if I recall.

But...the requirements went into effect like 40 years ago most places, so people under 50 would be the ones "protected" by it...but those are also the younger age groups that should have better outcomes regardless. But Belgium's late policy sort of points to it actually being a thing.


Something about SARS 2.0 and Rubella in particular having similar proteins(?), I believe, is the thinking.




Here's my post about the Tulane/LSU paper, with a link, from this thread a month ago.



Here's the paper looking at the other part of things regarding age groups.

WaWaWeeWa,

Would AIDS patients be a good test of this theory? That should provide low T-cell counts in younger patients (the majority of whom share a passion for either interior design or heroin use in the US, which may provide another avenue to find a statistical correlation).

In places like Africa, the average age skews a lot younger, but that’s in part because they die of AIDS...so is average T-cell functionality the same there as it is here?