Got a pounding headache from drinking a whiskey last night

One drink. Maybe two to the fingers deep with ice

I considered dehydration.

And no, it wasn’t my usual brand. But I’ve had it before

Vaginitis

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3 or 4 days a week at least in college

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One whiskey would do that to you in college? Lightweight.

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Your usual brand? If not, I’d suspect an allergy to something in the new variety.
Or you were already quite dehydrated before the alcohol kicked in, making it worse.f

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Allergy or enzyme changes. Age a factor in the latter.

All allergies require some kind of previous exposure. So it is only due to lack of education on allergies that it surprises people to suddenly come down with allergic reactions to stuff.

Both can be "age related". Changes over time to enzymatic systems of the body (think metabolism slowdown as we age and get that beer gut) or auto immune malfunction triggering the allergy could be the cause.

I get splitting headaches from a single draft beer. Bottled or canned is fine (not that canned draft stuff though, it hurts too). Liquor is no problem either, or was, chronic pancreatitis prevents me drinking now.

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One drink or one bottle ?

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One shelf

The whiskey could have been icing on the cake if what your diet was that day or last few days.

Heavy carbs, loads of sugars, lack of water, lack of veggies, lack of sun etc

Its called getting old