what point do you give up on the job search?

I got tired of working my low paying dead end job and decided to go back to school. I graduated from BRCC in December and have been applying to jobs since last year. According to indeed I applied to 15 jobs in the last two weeks, probably around 50 since the start of the year. Most of the time I never hear back from them. I would say I get an interview a little less than 10% of the time.

I was contacted by a recruiter a few weeks ago now I can't get him to respond. I have emailed employment agencies with barely a response. At this point it looks like I will never work in the field I'm trying to get into. I fear I will be forever stuck working dead end jobs. Is there a point where you give up on your dreams to just take whatever you can get? I want nothing more than to work and make a decent life for myself but it seems impossible now. I've got two college degrees in completely different fields and over 10 years of a stable work history and I can barely get companies to even talk to me. Getting harder and harder to stay positive but I still try.