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re: Semaglutide ban in Louisiana??
Posted on 4/21/23 at 10:28 am to bushwacker
Posted on 4/21/23 at 10:28 am to bushwacker
quote:
Source? I have lost 43lbs with 38 of that being fat. I weigh and get measured weekly, and do HIIT at the gym 3x per week.
quote:
Nadolsky highlighted subgroup data from the Step1 Study — semaglutide's primary clinical trial — which looked at 95 people who were on the drug and 45 people who received a placebo. The researchers conducted scans on all participants to monitor their body mass. Participants who received the drug lost an average of 10.4% of their fat mass and 6.9% of their lean body mass, and participants who received a placebo lost an average of 1.2% of their fat mass and 1.5% of their lean body mass.
1
Posted on 4/21/23 at 10:28 am to bazeball
quote:
Mounjaro is a more effective drug because of the addition of a secondary drug.
I've read it isn't a secondary drug but a different chain that works as both a GLP-1 and GIP Agonist.
Posted on 4/21/23 at 10:30 am to bazeball
quote:
This is an interesting topic for those of us that do clinic research trials with these drugs. The truth of the matter is that these drugs (loosely known as GLP1's) have changed the game. They basically force healthier behavior. They lower blood sugar levels and decrease appetite. Although everyone is talking about Ozempic, Mounjaro is a more effective drug because of the addition of a secondary drug. There are a few more drugs in the pipeline like Cagrilsema, which look to be even better still.
If the patient will take a fiber supplement each day and drink plenty of water, that will get rid of almost all side effects.
I know these aren't for everyone, but some of these will be fast tracked to a generic status. They are also working on oral versions. This stuff is not going away, no matter what Louisiana says.
which is a great thing. mounjaro isnt talking about as much because its harder to get for average non diabetic...atleast for now.
and from my understanding LA is just making the weight loss clinics go back to using the name brand, essentially protecting the patent which imo is right thing to do.
and yea these drugs are game changers for many. sure i can sit here and preach behavior change but 99% of people are not gonna do that
unfortunately the lack of behavior change also causes 99% of those on the medicine not to lift weights and priortize protien causing a lot of the weight lost to be from lean dry tissue ending with the patient being skinny fat in the end.
wish more doctors understood the importance of protein and progressive heavy weigth training on overall health.
keeo doing gods work
Posted on 4/21/23 at 10:31 am to lsu777
quote:
Being fat is a choice for almost all fatties. That truth hurts delicate snowflakes like Martini.
This is rich. I’m a delicate snowflake. Well I’ve been called worse.
Posted on 4/21/23 at 10:32 am to GhostofLesticleMiles
quote:
I would like for you to explain the subject matter to me and/or hear your input.
...and I would like you to silence yourself, but alas neither of us will get what they want.
Posted on 4/21/23 at 10:34 am to Proximo
quote:
Dr Nadolsky
Doc has had a ton of good stuff highlighting this issue.
granted some is because of water being considered lean tissue, still overall % is concerning but if you get down into the details...the patients were not using progressive resistance training nor tracking/priortizing protein.
even the guy you quoted, imo 5 lbs of lean dry tissue loss of an untrained individual is a lot. he would be much much better off stopping the HIIT and learning to lift starting with a linear progressin program like greyskull LP or wendlers 531 beginner prep school.
Posted on 4/21/23 at 10:34 am to Hu_Flung_Pu
quote:
I've read it isn't a secondary drug but a different chain that works as both a GLP-1 and GIP Agonist.
You are correct. For the sake of clarity, I didn't want to go into that detail in the post. The future of these "additives" is interesting. Whichever company figures out the best combination will have 3-4 years of massive profits.
Posted on 4/21/23 at 10:35 am to Hu_Flung_Pu
quote:
I've read it isn't a secondary drug but a different chain that works as both a GLP-1 and GIP Agonist.
this is correct
Posted on 4/21/23 at 10:38 am to bazeball
ftr CagriSema finshied phase 2 trials, showed 15% greater weight loss than semaglutide alone from what i read. Havent been able to see the study yet and look at the statistics but looks extremely promising
also greater than 20% reduction in overall bodyweight in 68 weeks.
also greater than 20% reduction in overall bodyweight in 68 weeks.
This post was edited on 4/21/23 at 10:40 am
Posted on 4/21/23 at 10:38 am to GreatLakesTiger24
quote:
a bunch of baws saying 1k for a long weekend and 5k for a family vacation was way too much
Much of it was making fun of the dweeb who claimed it was impossible to spend a leisurely weekend without spending 1k.
Posted on 4/21/23 at 10:40 am to LSUFanHouston
Tons of fast food threads, now the OT is talking about weight loss drugs. Sad.
Go outside, get some sunshine and exercise. You won't have to worry about drug side effects or being on a subscription plan to pharma companies.
Go outside, get some sunshine and exercise. You won't have to worry about drug side effects or being on a subscription plan to pharma companies.
Posted on 4/21/23 at 10:53 am to Long Ball Larry
quote:
...and I would like you to silence yourself, but alas neither of us will get what they want.
well ok..... Guess that is a no on your knowledge and input from properly researching the topic.
Posted on 4/21/23 at 11:11 am to lsu777
quote:
CagriSema finshied phase 2 trials, showed 15% greater weight loss than semaglutide alone from what i read.
I think it will prove much better than that. It's in phase 3 now.
LINK
That's as much details as we can give out legally. There are more in the pipeline as well.
Posted on 4/21/23 at 12:03 pm to RogerTheShrubber
quote:unless you're driving and staying at someone's house, it pretty much is
Much of it was making fun of the dweeb who claimed it was impossible to spend a leisurely weekend without spending 1k.
Posted on 4/21/23 at 12:05 pm to GreatLakesTiger24
Well my house is free and high life’s are only 2 bucks at Ivar’s
I’m not sure how y’all spend a grand on a leisurely weekend
I’m not sure how y’all spend a grand on a leisurely weekend
Posted on 4/21/23 at 12:09 pm to el Gaucho
are you staying at my place for essence fest this year?!?
Posted on 4/21/23 at 12:10 pm to LSUFanHouston
Meet me on the corner, cost $350
Posted on 4/21/23 at 12:13 pm to GreatLakesTiger24
Yeah girl all the hotels closed for renovations that weekend smh
Posted on 4/21/23 at 1:12 pm to GhostofLesticleMiles
quote:???
All I hear in here are a lot of excuses.
My post:
quote:
I do agree that a lot of the "just quit eating junk and exercise" posts seem flippant but I disagree with the quoted line because it implies that losing weight is easy for most (or many) people. It's not. It's "seriously hard" for those that manage to do it as well, and the fact that some people are able to do it and some people aren't doesn't mean that it's easier for people that are successful.
Where am I making excuses? If anything, I'm arguing against excuses.
Posted on 4/21/23 at 1:16 pm to Cosmo
quote:didn’t they recently ban a legitimate anti viral drug being used with success in the 2021-2022 timeframe?
Lol they cant ban a legitimate diabetes drug that is being used with success
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