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Italy Starts Mass Treatment with Hydroxychloroquine.. What are we waiting for?
Posted on 3/31/20 at 1:01 pm
Posted on 3/31/20 at 1:01 pm
LINK
TLDR; this drug works, it's inexpensive and easy to make, it will flatten the curve if given to the masses in the outpatient (clinic) setting, there are some minor side effects which are negated since this is just a 10-14 day dose, and the benefits far outweigh the rewards since we are seeing hundreds and thousands die daily
Really amazing quotes from Professor Christian Perronne, Head of the Infectious Diseases Department at the Garches University Hospital
TLDR; this drug works, it's inexpensive and easy to make, it will flatten the curve if given to the masses in the outpatient (clinic) setting, there are some minor side effects which are negated since this is just a 10-14 day dose, and the benefits far outweigh the rewards since we are seeing hundreds and thousands die daily
Really amazing quotes from Professor Christian Perronne, Head of the Infectious Diseases Department at the Garches University Hospital
quote:
We have just understood that the virus has an evolution in two phases and that it is during the second phase, after a few days (about a week), that the situation can suddenly, in 24 or 48 hours, worsen and leads to respiratory failure requiring intensive care.
quote:
The results that we are starting to accumulate suggest that hydroxychloroquine administered early, gives the possibility of avoiding this evolution in a majority of patients and is also helping us to prevent hospitals from filling up.”
quote:
“Even though the overwhelming evidence from large randomized studies is still lacking, I am in favor of a broad prescription for the following reasons:
1. We have a large body of evidence showing that in vitro hydroxychloroquine blocks the virus. We also have several clinical results indicating that this product is beneficial if administered early and we have no mention that it harms or is dangerous in this infection (only one study, poorly detailed, Chinese, on 30 patients with control group, did not observe any benefits but also no harmful effects). What is the risk of administering chloroquine straight away: nothing!
2. This drug is very inexpensive 3. It is well tolerated in long-term treatment. Personally, I have successfully used it clinically in the chronic form of Lyme disease for 30 years at a dose of 200 mg or even 400 mg/day.
quote:
Apart from these precautions, the undesirable effects are minor. They are even more so as the treatment is short, which is the case against Covid-19.
It would therefore be wise to produce hydroxychloroquine in very large quantities without further delay, to make it easily accessible to infected people…
I note that Italy has just authorized the wide distribution of hydroxychloroquine on medical prescription from the start of the infection and that other countries are preparing to do the same. What are we waiting for? To have more dead?”
Posted on 3/31/20 at 1:01 pm to OKtiger
Pretty sure this is happening now -- except for those state with a governor who forbade their docs to use it.
Posted on 3/31/20 at 1:02 pm to OKtiger
I haven’t a clue. I’ll ask my physician to contact his mentor at Johns Hopkins and we’ll get back to you.
Posted on 3/31/20 at 1:02 pm to OKtiger
quote:
it's inexpensive and easy to make
Surely we can come up with something way more expensive.
Posted on 3/31/20 at 1:02 pm to OKtiger
They worry about side effects, but light up cigarettes every day.
Posted on 3/31/20 at 1:03 pm to OKtiger
quote:
What are we waiting for?
Politics and optics.
Both of which are far, far more important than doing the right thing.
Posted on 3/31/20 at 1:04 pm to OKtiger
There are many many people in america who are actively hoping and praying right now that this drug is ineffective, because they want a certain person to look bad for offering it as a potential treatment.
They would rather people die than see this drug improve the situation.
They would rather people die than see this drug improve the situation.
Posted on 3/31/20 at 1:05 pm to OKtiger
Pretty sure it is being used widespread now. One of our own here is on it to fight COVID.
Posted on 3/31/20 at 1:05 pm to Cosmo
quote:
We are using it.
We are using it in patients on their death beds for the most part. The "point of no return" when you contract the virus.
It needs to be rolled out with mass treatment in the outpatient setting in the first 5-7 days to prevent hospital overcrowding.
Posted on 3/31/20 at 1:05 pm to OKtiger
Can I get an amazon link for a gross?
Posted on 3/31/20 at 1:05 pm to Centinel
This doesn't surprise me at all, it also wouldn't surprise me that we find out that Italy's hospital system is a giant clusterfrick of horrible administration that caused a lot of their issues that would not have otherwise happened in many other countries.
Posted on 3/31/20 at 1:06 pm to HailHailtoMichigan!
quote:holy hyperbole batman.
There are many many people in america who are actively hoping and praying right now that this drug is ineffective,
Posted on 3/31/20 at 1:06 pm to OKtiger
Is trustnodes a reputable news outlet? Just curious because I’ve never heard of it
Posted on 3/31/20 at 1:07 pm to baldona
quote:Italy's healthcare has been ranked 2nd in the world by some agenda-driven healthcare orgs for years now.
This doesn't surprise me at all, it also wouldn't surprise me that we find out that Italy's hospital system is a giant clusterfrick of horrible administration that caused a lot of their issues that would not have otherwise happened in many other countries.
obviously the rankings weren't accurate.
Posted on 3/31/20 at 1:07 pm to tiger91
quote:
Pretty sure this is happening now -- except for those state with a governor who forbade their docs to use it.
In Oklahoma, you need a positive COVID test to get a script as of now. I think there needs to be mass production and more leeway for physicians to get this script to patients who are waiting another 3-4 days for their test results since it has a very low side effect profile
Posted on 3/31/20 at 1:08 pm to S
quote:
I’ll ask my physician to contact his mentor at Johns Hopkins and we’ll get back to you.
Posted on 3/31/20 at 1:10 pm to OKtiger
quote:
It needs to be rolled out with mass treatment in the outpatient setting in the first 5-7 days to prevent hospital overcrowding.
Agree, if available quantities and ability to produce as needed are there.
Posted on 3/31/20 at 1:10 pm to OKtiger
quote:to see how well they live
What are we waiting for?
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