New deer rifle for my 21 year old daughter

7mm08

7mm-08 Bergara Ridge with a Leupold VX freedom. That would be the prime setup you just described.

What's your budget?

Ruger American is a very good rifle for not much money.
The OB standard bearer is the Tikka.

As to calibers, most any caliber will perform wonderfully if you make a good shot. All calibers will perform badly if it isn't a good shot.

in no particular order: .308, 7mm-08, 6.5 cm, 6.5 prc are all caliber that will have about the same amount of recoil and will take any game in the southeast easily. The .308 and 6.5 cm will be two of the easiest to find ammo for. Just make sure the ammo you buy is for hunting and not for match.

As to scopes, I'm a fan of the Leupold VX5 hd 3-15x44.
A leupold VX3 hd is also a good scope with good glass.
Burris makes a very good scope as well.
A Trijicon Huron is a very good scope for less money and it's bulletproof. a 2.5-10x40 would be a great scope for her.

7mm-08 in a Weatherby Vanguard Camila, stock is very different from a man's and is cut for a woman. My wife has the Vanguard in 7-08 and the Mark V in 280AI, both are fantastic for her and don't fit me worth a damn.


Weatherby

My daughter is 12. She shoots a bergara stoke in 6.5 prc. Has a muzzle brake. Great gun and easy shooting. Is the compact version wt a 20 inch barrel.

Does she have any interest in a larger caliber and more recoil? A .243 is in a different recoil class than the other options. Perhaps she can handle more. But a .243 is a material step down in recoil and that may matter. If she can in fact handle more gun, I'd get a Weatherby Vanguard in .25-06. Weatherbys weigh a little more than other alternatives and that's a good thing. They also have long barrels which is also a benefit.

PCBourbon,
It's good you're helping your daughter get into deer hunting. Nowadays there are a number of good deer rifles available that won't break your bank. I'd suggest one of the following bolt actions: Ruger American, Savage, Browning or Howa. I don't have a Tikka, but I've read good reviews and they have a strong following on the OB. I've got a Marlin that I've been very pleased w/, but not everyone's had the same experience. he Remington 700 has historically been a good gun, but due to recent QC problems, I can only recommend an older model, Bergara also makes a nice bolt gun. I suggest you take her to a gun store and handle different models and see which one (s) handle most naturally.. Notice how the safety and bolt work. Depending on her nature, she might find a "youth" model fits her best.

As far as what caliber, I'd suggest one of the following: 25-06, 260 Rem, 270 Win, 7-08, 280 Rem, 308 Win or 30-06. 6.5 Creedmore is ok as long as you can find ammo w/ good deer hunting bullets, NOT match bullets. The 350 Legend and 300 Blackout are also good rounds to start w/, but they do limit the range. When my son started deer hunting, I bought him a 308 and loaded some reduced recoil loads for him (this was prior to factory reduced recoil loads). He killed a bunch of deer w/ it. Now that my grandson's are nearing deer hunting age, I have bought a 7-08 for them to hunt with. If she's recoil sensitive, shoot some managed recoil loads before you start using full power loads. You don't need a magnum, short, long, ultra____, or whatever. Buy a decent scope in the 3-9X range. You don't need to spend $600 on the scope. The brands I can personally recommend are Leupold, Burris and Vortex. I use a one piece Weaver base and Burris Signature Z rings (the ones w/ the plastic inserts) to attach the scope on all my guns. Try different types of ammo before settling on which one to hunt w/. Keep in mind what calibers of ammo are available where you shop. For example, my local WM doesn't even carry 7-08 ammo.

I also like the idea of getting a suppressor for the new gun, especially since the tax stamp fee is gone. The 30 caliber suppressors I can personally recommend would be Dead Air Nomad L and Otter Creek Labs Polonium 30. If you buy one of the less expensive guns, you'll have plenty of money in your budget for a suppressor.

Keep us updated. I hope y'all experience some good memories hunting together.

270 win is awesome but my favorite is 7mm08

Tikka is awesome and so accurate out of the box. Get the ultralight in 270