TigerOnThe Hill

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"Big Pharma" has put out many meds that will help you live longer to cry more about "Big Pharma."

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Yes, "Big Pharma" had developed many life saving drugs, but I stand by my initial comment. Many folks are unhappy w/ "Big Pharma" now days, not because of life saving drugs, but because it has proliferated many other non-"life saving," drugs. Many complain how "Big Pharma" has pushed these drugs on prescribers as well as the public. Remember "Direct to Consumer" advertising? In addition, "Big Pharma" spends a lot of money developing and marketing "me too" drugs, not new drugs. How many GLP1's are needed? How many Zolofts are needed? For comparison:

Anxiety meds. In 1976, there was a handful of anti-anxiety meds (benzodiazepines like Valium and Librium) on the market. Now there are many more BZs and use has shifted to Ativan , Klonopin and Xanax. The diagnosis of Benzodiazepine use disorder didn't even exist in 1976, but it does now. AI says, "Approximately 3.4% to 12.6% of U.S. adults use prescription benzodiazepines annually...About 2.1% to 2.2% of the adult population engages in BZD misuse."

Opioids. Remember the "opioid crisis?" In 1976 opioids were reserved for very short term use. Long term use was only for unfortunate people dying of cancer. The "opioid crisis" started in the 90's and was a direct product of "Big Pharma", especially Purdue Pharmaceuticals. Yeah, professionals prescribed the meds, but Purdue corrupted and lied to the FDA and deceived prescribers. According to AI, "In 1976, Opioid usage was strictly medical. Prior to the heavy marketing of extended-release opioids in the late 1990s, community-based or non-medical use of prescription opioids was negligible... According to data reported by the NCDAS, 3.2% of adults and 2.2% of youth use prescription pain medications."

I graduated from high school in 1976. At the time, I'd never heard of anyone dying from an opioid overdose. High school graduates can't say that now. Approximately 100,000 Americans die annually from opioid overdose, although decreasing the past 3 years.

Depression meds: Admittedly, the treatment of depression has advanced, but a lot of the increase in the use of anti-depressants has been driven by "Big Pharma." For comparison, AI says "Antidepressant use in the United States skyrocketed from an estimated 1% to 2% of the population in 1976 to roughly 11.4% to 16.6% of adults in 2026." Sometimes it seems like everyone is taking Zoloft, Lexapro or Prozac.

U.S. life expectancy at birth has increased by nearly 6.5 years, rising from 72.6 years in 1976 to approximately 79 years today. That is a very modest increase and is largely not due to "Big Pharma." According to AI, "This major gain is primarily due to drastic reductions in infant mortality, improved treatments for heart disease, and declining smoking rates."

Admittedly 1976 was not perfect, but many aspects of it were better than now.

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feelings woah woah woah feelings

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I see what you did there. Nice touch. :lol:

FIFY

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I mean if they want to waste their benefits and the taxpayers money on junk I say let them. :idk:

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Hopefully he didn’t blow it betting the unders in the Chinese Basketweaving Association.

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Given his history, the money's probably already gone.

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go to a running specialty store and they will examine your stride and make several recommendations based on that, and you can go from there.

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Good advice.....generally speaking. I'll explain later. I've been running (now walking after arthroscopic knee surgery) pretty continuous since 25 years. Early on, I had an episode of plantar fasciitis. Had to take off 6 months for it to resolve. Before I started back running, I went to a running store in Shreveport. I explained my needs to a young, pretty female salesman. She came out w/ many pairs of shoes to try. I put n the first pair and she said, "Isn't that a pretty color." :lol: I asked for a different salesman and got a grizzled looking 30ish guy who cared less about color. Ended up w/ a pair of Asics. Wore the same model of Asics until just recently. I usually get a new pair at 300-350 miles, but the last 2 pairs of Asics wore out LONG before that. Now I'm wearing a pair of Sketchers. They seem ok, although they're not a "pretty" color. :cool: I've not had anymore plantar fasciitis ever since.

This web page has a lot of good info.

Check out this page and figure out your degree of pronation

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Show that were not that good when the main character left

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"NCIS" clearly lost its fastball when Special Agent Gibbs' (Mark Harmon) character left the show.

Hey guys,
Yesterday I received an order of small rifle primers from White River Energetics from Ravens Rock Precision.. The price was really good at $145, although I had to buy 2000 w/ free shipping and haz mat. Factory seconds are $10/2000 cheaper. The primers are made in Des Arc, AR. I remember reading about the company start up a few years ago, but I've not seen them for sale until now. I hope to give them a try in a few weeks. I didn't see any magnum SR primers for sale. I wonder if this is the same White River that got Bill and Hillary Clinton in trouble while he was president? :confused:

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At the end of the day a 125-150gr modern design bullet moving 3000fps is all anyone needs

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True, as long as you're not hunting some of the. 100-150# whitetail deer wearing body armor. :lol:

Our guns are already plenty powerful and flat shooting for big game hunting. Nevertheless, hunters (myself included) are always open to the idea of a new cartridge that'll require a new gun. :nana:

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For starters, irregardless is not a word. I guess adding Re in front cancels out the ir, and thus makes it correct?

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Maybe it's a word when you add the u??

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Reirreguardless

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Some lessons are hard. Hope she learns from something from this one.

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All very true, but she didn't learn anything good from it. At the very end of the video she basically said she'd do it again.

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He may not win cause it’s too steep a hill to climb. But his commercials are GOLDEN.!!!!!

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The biggest winner from the L.A. mayoral race will be Pratt's political consultants. :bow: They've done a masterful job w/ his ad campaign. :nana: