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re: Study finds GLP-1 drugs cause a drop in violent behavior

Posted on 7/2/26 at 6:28 am to
Posted by SallysHuman
Lady Palmetto Bug
Member since Jan 2025
23912 posts
Posted on 7/2/26 at 6:28 am to
quote:

I have had more than one patient tell me that the meds have caused them to not like the taste of alcohol. Less drunks = less brawls.


My husband is on the 4mg Wegovy pill… it surprisingly has NOT lessened his drinking.
Posted by Night Vision
Member since Feb 2018
22863 posts
Posted on 7/2/26 at 6:56 am to
quote:

caused them to not like the taste of alcohol.


What alcohol doesn't taste like crap?
Posted by funnystuff
Member since Nov 2012
9204 posts
Posted on 7/2/26 at 7:00 am to
Y’all need to read this article more carefully…
quote:

Their main analysis concentrated on 821 people who had used a GLP-1 medication at some point.
quote:

Across the full sample, higher levels of impulsivity and greater alcohol use were both strongly linked to violent behavior.
quote:

The strongest finding in the study was that the well-established link between impulsivity and violent behavior was substantially weaker among current GLP-1 users compared to former users
This doesn’t necessarily tell us that GLP1s lower the proclivity for violence. They identify that there is still a strong link between impulsivity and violence for current GLP1 users.

They only say that that link is weaker in current users than in former users. Yes, the hopeful possibility is that the current use of GLP1 is weakening the urge to violence… but the more troubling possibility is that the withdrawal of the GLP1 is raising the urge to violence.

This paper is 100% consistent with a hypothetical story that says ending a GLP1 treatment will increase the former user’s proclivity for violence. Since the authors confusingly did not include the baseline associate for the full population (which is itself suspect), we just have to hope that the violence increase for former users is a jump that returns to baseline rather than a jump that exceeds baseline.
Posted by RoyalWe
Louisiana
Member since Mar 2018
5173 posts
Posted on 7/2/26 at 7:05 am to
quote:

I work closely with endocrinologists and they are completely safe.
We have evidence on this very board that GLP-1s cause avid exercise enthusiasts to become violent.
Posted by kciDAtaE
Member since Apr 2017
17703 posts
Posted on 7/2/26 at 7:19 am to
quote:

With GLP drugs there is no free lunch
isn’t that the point
Posted by Big EZ Tiger
Member since Jul 2010
26828 posts
Posted on 7/2/26 at 7:28 am to
Yeah, violent eating.
Posted by Cotten
Tennessee
Member since Jan 2018
1845 posts
Posted on 7/2/26 at 7:35 am to
quote:

I work closely with endocrinologists and they are completely safe.

Completely safe? Hmm, where have we heard that before.

Btw, what happened to all those completely safe folks with paralyzed stomachs from GLP-1s?
Posted by BeachDude022
Premium Elite Platinum TD Member
Member since Dec 2006
36518 posts
Posted on 7/2/26 at 7:35 am to
quote:

My husband is on the 4mg Wegovy pill… it surprisingly has NOT lessened his drinking.


The pill is garbage. Stick with injections.
Posted by wareaglepete
Union of Soviet Auburn Republics
Member since Dec 2012
19037 posts
Posted on 7/2/26 at 7:38 am to
quote:

My husband is on the 4mg Wegovy pill… it surprisingly has NOT lessened his drinking.


The pill is garbage. Stick with injections.


And 4mg ain't shite.
Posted by MFTPC
Member since Apr 2026
93 posts
Posted on 7/2/26 at 7:43 am to
Put it in the Mississippi river like fluoride.
Posted by CleverUserName
Member since Oct 2016
17834 posts
Posted on 7/2/26 at 7:46 am to
I think that reason could be linked to the same reason Victoria's Secret stores are beginning to see a boom in sales.
Posted by SallysHuman
Lady Palmetto Bug
Member since Jan 2025
23912 posts
Posted on 7/2/26 at 8:03 am to
quote:

Stick with injections.


He’s dropped about twenty pounds and the pill is only $149.

I considered it.. but there’s no way I’d be able to get my protein in, so I’m losing mine the regular way.
Posted by GreatLakesTiger24
Member since May 2012
61096 posts
Posted on 7/2/26 at 8:33 am to
quote:

I work closely with endocrinologists and they are completely safe.
never heard this one before
Posted by Gifman
Captiva, FL
Member since Jan 2021
19240 posts
Posted on 7/2/26 at 8:36 am to
Enjoy your massive muscle loss and bone density deterioration
Posted by HeadSlash
TEAM LIVE BADASS - St. GEORGE
Member since Aug 2006
56258 posts
Posted on 7/2/26 at 8:45 am to
Now available on WIC? Whitey trying to keep me thin and docile.
Posted by GreatLakesTiger24
Member since May 2012
61096 posts
Posted on 7/2/26 at 8:50 am to
quote:

Now available on WIC?
there’s a new Medicare program for boomers who can’t afford it
Posted by nuwaydawg
Member since Nov 2007
2358 posts
Posted on 7/2/26 at 9:21 am to


Drucker had read about the work of endocrinologist John Eng, gastroenterologist Jean-Pierre Raufman and biochemist John Pisano, who had sequenced the proteins in Gila monster (Heloderma suspectum) venom and found two that looked like human GLP-1.

Drucker and his team from the University of Toronto acquired a Gila monster from the Utah Zoo's breeding program to dissect for further research. This work confirmed that the lizard species' unique genes produce a protein, Exendin-4, that fit the bill, mimicking GLP-1 while hanging round in the human body for far longer.

A synthetic version was created in the years after, but it took until 2005 for this GLP-1 agonist to become an FDA-approved treatment for type 2 diabetes. It's now also become a popular treatment for obesity, with further potential applications on the horizon.

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