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re: Patients taking Eli Lilly's retatrutide lost 58 pounds, on average, in a phase 2 clinical
Posted on 8/30/23 at 8:36 am to lsu777
Posted on 8/30/23 at 8:36 am to lsu777
quote:
thats what you dont understand and many dont. many times these are lifetime drugs
Here is my lone issue with that - I spoke to the guy at my gym who is on this. For him it is only $100/month with his insurance. For some people it is as low as $50. I have heard some are paying $500 and some even $1000. What happens to the group who are paying $500/$1000 a month when they lose their job and no longer have insurance? Keep in mind most employers these days are providing worse and worse ins coverage the ones that are paying $100 month for Mounjaro/Ozempic are the lucky ones. Unless our benevolent govt subsidizes this for all (and they very well might at some point) it isn't going to be sustainable because of simple life changes or events like losing job etc. Short term this can work but long term I don' see people sticking to this. We have people that whine and complain about insulin prices and claim they can't afford it but they will be able to afford this for infinity plus have the willpower to keep using? I just don't see it. Basic dietary and exercise changes is the long term answer not some magical concoction.
1
Posted on 8/30/23 at 8:37 am to Eurocat
I need to find that post from a few years ago where I said that GLP-1 agonists were going to be used to get out of the obesity epidemic. Presicent.
Posted on 8/30/23 at 8:37 am to schwartzy
quote:
A pill can’t be the solution for everything.
Do you even America 2023, bro?
Posted on 8/30/23 at 8:38 am to crazy4lsu
A lot of housewives take Wellbutrin for weight loss and depression
Posted on 8/30/23 at 8:39 am to ronricks
quote:
Does this cause zombie o-face?
thats caused by couple things
1) people stretch their skin out so much, it cant snap back. loss of elasticity. happens in the face and everywhere. Especially in the older 40+ crown
2) they are eating very little and still living shitty lifestyle so their hormones, specifically IGF levels are in the basement. For males, testosterone too many times and this causes the loss of muscle and the lack of snap in the skin
3) lack of calories and lack of protein. many on this are eating 1000 cals or less and very very little protein. they are trying to take it off way fast than they put it on
for most on this, they should be shooting for around 1-1.5 lbs of weight loss per week. about 75 in a year. more than that and calories are too low and skin will be stretched and not come back
combine with high protein 40-50% of calories and progressively lifting and you have the bones of a lifetime program that can be followed and will actually make you look better naked
but we see it on the H&F board all the time...people say...only want to do cardio right now until i lose a lot of weight because people want it off and want it gone now
i do find it funny though that multiple people who are confirmed obese through pics or height/weight they have posted are bashing this medicine.
Posted on 8/30/23 at 8:39 am to Eurocat
quote:
An experimental drug from Eli Lilly has the potential to provide greater weight loss benefits than any drug currently on the market.
quote:
The experimental drug
I'm amazed at what people will do to avoid a reasonable diet and a moderate level of exercise. They'd rather take an experimental drug for the rest of their lives.
Posted on 8/30/23 at 8:40 am to JasonDBlaha
quote:I get this sentiment and would have agreed with it up into my 40s. Currently, I don't have as harsh a position. Things change as you get older. Some people don't have the luxury of focusing on themselves because of the needs of loved ones. Your body also turns on you as old age gives you more pains and limitations. If a pill or injection can provide tremendous health advantages in spite of poor eating or exercise habits, then thank God for modern medicine. I'm pretty sure we're all humbled in the end, so I'll take what I can when I can.
Imagine having to take a pill to lose weight when all you have to do is simply eat a little less food and move around more.
Posted on 8/30/23 at 8:45 am to ronricks
can get it on the gray market from reputable companies for no more than $120 for 3mg. maintenance dose can be less than 1mg a week.
but in the end, people in the situation you described are going have to either find alternatives or learn to do it through exercise and diet
cant plan for every alternative and most poor people are that away because they make poor decisions. is what it is, cant save everyone
but i am fine with better living through chemistry
these drugs arent my thing and prolly never will be. when i was 245lbs and fat as frick, what motivated me to get back in shape was not being able to tie my shoes without getting out of breath and the fear i would fall over with a heart attack while playing catch in the front yard with my kids.
some people just are weak and dont have the will power that people like you and I have. if this medicine helps them...cool. hopefully they learn discipline along the way instead of depending on motivation.
but in the end, people in the situation you described are going have to either find alternatives or learn to do it through exercise and diet
cant plan for every alternative and most poor people are that away because they make poor decisions. is what it is, cant save everyone
but i am fine with better living through chemistry
these drugs arent my thing and prolly never will be. when i was 245lbs and fat as frick, what motivated me to get back in shape was not being able to tie my shoes without getting out of breath and the fear i would fall over with a heart attack while playing catch in the front yard with my kids.
some people just are weak and dont have the will power that people like you and I have. if this medicine helps them...cool. hopefully they learn discipline along the way instead of depending on motivation.
Posted on 8/30/23 at 8:46 am to Eurocat
I was a dumbass when I initially got off active duty and didnt watch what I ate. All of a sudden my problems went away after a month of eating right. I will say that it seems pretty easy to frick up your lifestyle because it's not. I'm not gonna blame others for my mistakes and most people wanna act like some boogeyman made them eat a box of twinkies everyday. Ever wonder why the sugar industry in negative light is a thing.
Posted on 8/30/23 at 8:47 am to RoyalWe
quote:
Your body also turns on you as old age gives you more pains and limitations
no it doesnt. it just adapts to the sedentary lifestyle so many adopt as they get older. if talking 70+ sure but not in your 40s or 50s or even 60s.
rest of your post i agree 100% with
Posted on 8/30/23 at 8:48 am to Aubie Spr96
quote:
The experimental drug
its only experimental because it hasnt gotten full approval yet for obesity. its approved and not experimental for the treatment of diabetes.
Posted on 8/30/23 at 8:53 am to Eurocat
quote:
Patients taking Eli Lilly's retatrutide lost 58 pounds, on average, in a phase 2 clinical
I bet this flies through FDA approval.
Posted on 8/30/23 at 8:58 am to lsu777
quote:Biology is complicated in that people are different and age differently. Part of that is genetics and part of it is how you live. Regardless, we're all going down the same path just maybe at different speeds and for different reasons. Those who choose to be sedentary and eat poorly should not be celebrated or absolved, but recognize that many do not choose that path.
no it doesnt. it just adapts to the sedentary lifestyle so many adopt as they get older. if talking 70+ sure but not in your 40s or 50s or even 60s.
Posted on 8/30/23 at 9:02 am to RoyalWe
quote:
Biology is complicated in that people are different and age differently. Part of that is genetics and part of it is how you live. Regardless, we're all going down the same path just maybe at different speeds and for different reasons. Those who choose to be sedentary and eat poorly should not be celebrated or absolved, but recognize that many do not choose that path.
agree but my point is.....for the most part...life doesnt just start giving yu all kinds of pains as you age until you are 70+
your metabolism also doesnt slow very much. we know that for a fact. it only slows about 10 calories per decade of life after 30.
Posted on 8/30/23 at 9:04 am to northshorebamaman
quote:
I agree with you in principle, but, at the same time, Americans are fat as frick. And I have little hope that greater than 5% of Americans are going to do anything to improve their diets. Maybe you are anticipating a wave of healthy eating and personal accountability but I am not so optimistic.
As cold as it may sound, IMO, all these new weight loss drugs are dependent on cost/benefit. Do the potential benefits of these drugs in regards to money saved on treating chronic diseases caused by obesity outweigh the side-effects?
Americans aren't going to change their lifestyles. That's on them. Will these drugs help curb the ridiculous amounts of money spent on healthcare for fat people? I don't know, but if so they should put it in the tap water.
/thread
Posted on 8/30/23 at 9:05 am to Eurocat
What's the fat to lean mass breakdown?? That's what they never study... if you are obese, last thing you need to loose is lean mass... trust me, I'm Fatman
Posted on 8/30/23 at 9:06 am to wallowinit
quote:
You couldn’t be more right in my opinion. I don’t know why people are down voting you for this
Because those are the people who want these magical diabetic drugs vs changing their lifestyle and putting in the hard work.
Posted on 8/30/23 at 9:09 am to stuntman
Disease definition:
Let it go my man, hearing people calling obesity a disease is hardly worth getting upset about.
quote:
A condition or tendency, as of society, regarded as abnormal and harmful
Let it go my man, hearing people calling obesity a disease is hardly worth getting upset about.
This post was edited on 8/30/23 at 9:10 am
Posted on 8/30/23 at 9:09 am to FatMan
quote:
What's the fat to lean mass breakdown??
Well, if it curbs the appetite and boosts metabolism, then a good portion of it is muscle loss.
Just like you cannot target where you are losing fat when dieting/training, these drugs don't discriminate between fat/lean mass.
Posted on 8/30/23 at 9:11 am to MrJimBeam
quote:
I agree with you in principle, but, at the same time, Americans are fat as frick. And I have little hope that greater than 5% of Americans are going to do anything to improve their diets. Maybe you are anticipating a wave of healthy eating and personal accountability but I am not so optimistic.
As cold as it may sound, IMO, all these new weight loss drugs are dependent on cost/benefit. Do the potential benefits of these drugs in regards to money saved on treating chronic diseases caused by obesity outweigh the side-effects?
Americans aren't going to change their lifestyles. That's on them. Will these drugs help curb the ridiculous amounts of money spent on healthcare for fat people? I don't know, but if so they should put it in the tap water.
quote:
/thread
Perpetual reliance on the drug isn't the answer. Since they do not change their lifestyle, they will have to stay on the drug 24/7 or just become a huge fat-arse again.
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