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re: Patients taking Eli Lilly's retatrutide lost 58 pounds, on average, in a phase 2 clinical

Posted on 8/30/23 at 9:20 am to
Posted by lsu777
Lake Charles
Member since Jan 2004
31402 posts
Posted on 8/30/23 at 9:20 am to
quote:

Well, if it curbs the appetite and boosts metabolism, then a good portion of it is muscle loss.


FTR none of these drugs boost metabolism

quote:

Just like you cannot target where you are losing fat when dieting/training, these drugs don't discriminate between fat/lean mass.




correct

as far as the ratio....that all depends on the person taking it

if you eat very little protein and do not lift weights....the ratio skews to 50/50 or even up to 60% of loss from lean mass in the 60+ crowd which is fricking insane. Those are for people eating less than 1200 calories

for those prioritizing protein, lifting progressively it was like 8:2 even 9:1 bodyfat to muscle loss. which is in line with what we usually see from those that arent taking the medicine

sleep is the biggest overlooked factor too in these things. talking 50% difference in body fat loss when sleep is cut from 8 hours to 6 hours.

so ratios are individualistic but seems if you try and stay on the same lifestyle you had before with shitty diet consisting of processed fatty/sugary foods...gonna just be skinny fat with lots of excess skin





FTR imo a ghrh/ghrp combo should be prescribed with these things to help skin elasticity and fat loss. All patients should be referred to a nutrition/lifting coach and insurance should require compliance to cover it. but thats asking way too much.
Posted by TigerRagAndrew
Check my style out
Member since Aug 2004
7218 posts
Posted on 8/30/23 at 9:25 am to
For someone working 10-12 hours a day, commuting another 2, there isn't much time or energy to prepare healthy meals, eat right, or exercise. Also it's hard as hell to get 8 hours of sleep during the night due to having to corral kids. None of this adds up to the ability to lose weight on our own.
Posted by Cosmo
glassman's guest house
Member since Oct 2003
120379 posts
Posted on 8/30/23 at 9:25 am to
quote:

Calories in < calories out That's the key to weight loss. Bottom line


Yes though where the calories come from also matters
Posted by Obtuse1
Westside Bodymore Yo
Member since Sep 2016
25809 posts
Posted on 8/30/23 at 9:28 am to
quote:

You get this message of self-discipline out of here



Hold up! I missed this earlier but did YOU just invoke the idea of self-discipline regarding weight control?????



Posted by LSUAlum2001
Stavro Mueller Beta
Member since Aug 2003
47138 posts
Posted on 8/30/23 at 9:28 am to
I just hope we don't see these commercials in the future..

quote:

If you were prescribed Mounjaro, Ozempic, Retatrutide, etc, you may be eligible for compensation..
Posted by Cosmo
glassman's guest house
Member since Oct 2003
120379 posts
Posted on 8/30/23 at 9:28 am to
quote:

For someone working 10-12 hours a day, commuting another 2, there isn't much time or energy to prepare healthy meals, eat right, or exercise.


bullshite

Takes 5 minutes to make eggs with some bacon or ham.

Can do a chicken and veggie dish in 10 minutes
Posted by LSUAlum2001
Stavro Mueller Beta
Member since Aug 2003
47138 posts
Posted on 8/30/23 at 9:30 am to
quote:

bullshite

Takes 5 minutes to make eggs with some bacon or ham.

Can do a chicken and veggie dish in 10 minutes


This.

You make the time. Meal prep on Sunday's for an hour or two.
Posted by MrJimBeam
Member since Apr 2009
12352 posts
Posted on 8/30/23 at 9:30 am to
quote:

Perpetual reliance on the drug isn't the answer. Since they do not change their lifestyle, they will have to stay on the drug 24/7 or just become a huge fat-arse again.



Some may rely on it because they will always be lazy. Others might actually decide to change their lifestyle because they haven't been this skinny in their entire adult life. Keeping everyone fat doesn't exactly solve anything either. At least this helps everyone to potentially push them into a new life they used to know or never knew.
Posted by LSUAlum2001
Stavro Mueller Beta
Member since Aug 2003
47138 posts
Posted on 8/30/23 at 9:31 am to
quote:

Keeping everyone fat doesn't exactly solve anything either.


No one is keeping them fat except themselves.
Posted by lsu777
Lake Charles
Member since Jan 2004
31402 posts
Posted on 8/30/23 at 9:33 am to
quote:

For someone working 10-12 hours a day, commuting another 2, there isn't much time or energy to prepare healthy meals, eat right, or exercise. Also it's hard as hell to get 8 hours of sleep during the night due to having to corral kids. None of this adds up to the ability to lose weight on our own.



a) you need to find a better job and something closer or move closer

B) are you serious that you are spending 14 hours a day on work???? thats fricking insane.

C) it takes about an hour to 90 min to grill chicken breast and cook eggs for 4 days. do that every sunday and repeat on wednesday night. time is not an excuse when it comes to eating healthy, thats bullshite

d) as far as time to exercise......20 min of calisthenics every week day is enough to get a good workout in to stay strong and healthy. you have 20 min



but why the frick are you sacrificing your health, your families health, your whole fricking life for a job that is costing 60% of your life every day? frick that

what do you do?
Posted by lsu777
Lake Charles
Member since Jan 2004
31402 posts
Posted on 8/30/23 at 9:34 am to
quote:

No one is keeping them fat except themselves.


at the same time, why do you care what other people take?

do you care if people take steroids?

it doesnt affect you so who gives a frick?
Posted by LSUAlum2001
Stavro Mueller Beta
Member since Aug 2003
47138 posts
Posted on 8/30/23 at 9:38 am to
quote:

at the same time, why do you care what other people take?


..because it's a lazy excuse. Woe is me! The world is keeping me fat!

..and like other miracle drugs what are the long term affects of something like this? If there are any, then everyone will be paying the price as countless lawsuits start to roll in.
Posted by deathvalleytiger10
Member since Sep 2009
7609 posts
Posted on 8/30/23 at 9:41 am to
quote:

those lifting and hitting protein goals of 1g per lbs of bodyweight do not show muscle loss



Those doing this probably don't need the pill. And good luck getting them to start lifting and eating properly now. It isn't going to happen except in a rare case of an individual that is really committed.

Peter Attia talks about his patients and how the lean muscle loss exceeded his expectations. He tracked this with DEXA scans before and after the use of these meds.

There is a definite trade off. Now, what does that mean long term? We shall see.
Posted by GRTiger
On a roof eating alligator pie
Member since Dec 2008
63177 posts
Posted on 8/30/23 at 9:42 am to
quote:

because it's a lazy excuse. Woe is me! The world is keeping me fat!


Ignore all that. The side effects argument is fine, but I'd rather have a skinny population that largely cheated than a morbidly obese population dragging us all down with their "handicap."
Posted by lsu777
Lake Charles
Member since Jan 2004
31402 posts
Posted on 8/30/23 at 9:46 am to
quote:

..because it's a lazy excuse. Woe is me! The world is keeping me fat!


again how does this affect you? these people do that if they take it or dont take it, so how is this changing.

stop being emotional.

quote:

.and like other miracle drugs what are the long term affects of something like this?


its a glp1 antognist. been studyed for almost two decades and been used for diabetes treatment for a long time.



quote:

then everyone will be paying the price as countless lawsuits start to roll in.


why would everyone pay? there are already lawsuits for the medicine doing exactly what it is advertised to do. why would the taxpayers pay that vs the company? explain like i am 5 please.
Posted by Shamoan
Member since Feb 2019
9270 posts
Posted on 8/30/23 at 9:47 am to
why do people seem upset that there is another option other than the "old fashioned way"?
Posted by LSUAlum2001
Stavro Mueller Beta
Member since Aug 2003
47138 posts
Posted on 8/30/23 at 9:47 am to
quote:

why would everyone pay? there are already lawsuits for the medicine doing exactly what it is advertised to do. why would the taxpayers pay that vs the company? explain like i am 5 please.


Lawsuits drive the cost up for everyone.

Posted by lsu777
Lake Charles
Member since Jan 2004
31402 posts
Posted on 8/30/23 at 9:48 am to
quote:

Those doing this probably don't need the pill. And good luck getting them to start lifting and eating properly now


thats why i said if its used as a kick start for a healthier lifestyle

quote:

Peter Attia talks about his patients and how the lean muscle loss exceeded his expectations. He tracked this with DEXA scans before and after the use of these meds.



yea read that and saw some other research on it. thats where i got my numbers from


again it is a trade off. but those that us it...will be smaller which has health benifits in and of itself

those that take it and use it as a jump start will see major changes for the better health wise and look way better naked.
Posted by lsu777
Lake Charles
Member since Jan 2004
31402 posts
Posted on 8/30/23 at 9:50 am to
quote:

Lawsuits drive the cost up for everyone.


sure if they are wide spread...they arent and wont be

so in your opinion should we stop all development of medicine because could drive the price up?

should we stop all research into medicines that can help us live better through chemistry?

i mean most things, even cancer, can be attributed to lifestyle choices and BF%....should we just stop trying to treat disease?

just wondering where you draw the line
Posted by lsu777
Lake Charles
Member since Jan 2004
31402 posts
Posted on 8/30/23 at 9:54 am to
quote:

why do people seem upset that there is another option other than the "old fashioned way"?




because they are low IQ. its the same people who get mad about editing of photos or people taking steroids are any other thing you can think of.....it makes them feel bad about themselves

i dont take this shite and never will but it literally affects my life none if someone else does...literally zero

someone loses bunch of weight on it and becomes ripped...looks better than me...cool who gives a frick

someone takes steroids and becomes bigger, stronger and more ripped than me....cool, who gives a frick

someone edits their pictures and looks bigger, more ripped and better than me...cool, who gives a frick


point is people get mad because of jealousy. they will deny it but its envy in many cases

now in some cases on here...its people wanting others to make healthier lifestyle choices and just be better overall in life. I certainly understand that, but its not living in reality.
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