re: Paging the horse paste deniers - FDA loses it's war on Ivermectin

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The leftist war on ivermectin was insane like most of their covid policy was.

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a letter has been issued to retract it

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This Expression of Concern does not imply that the methodology used by Mr. Andrew Bryant and his collaborators was incorrect. The use of summary data published by others is a generally accepted approach in biomedical metanalytic research.1

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Literally every single thing they made SOME of us do was wrong

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I think my HVAC guy could probably go toe to tow with them in the IQ department frankly.

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this one?

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In their original meta-analysis, Bryant et al3 performed sensitivity analyses to assess robustness of their results by performing trial sequential analysis to confirm that ivermectin reduced mortality. Reanalysis of the study by Niaee et al showed that it should have been recategorized as having a high risk of bias and excluded during sensitivity analysis.24 This study had data and statistical errors previously described and included PCR-negative patients with different between-group PCR positivity, BMI, oxygen saturation, and initial CT performance, indicating randomization failure. In our opinion, these issues require removal of this article from any meta-analysis. Importantly, this was the only article within the Bryant meta-analysis showing that ivermectin reduced mortality.4 Removal of this single article alters their results so that no significant difference now exists between ivermectin and control mortality (risk ratio, 0.73; 95% CI, 0.45–1.18).

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It was silly to ever paint it as "horse medicine," yes.

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Mr. Alderson got started with 10 rounds of radiation therapy. Initially, his carcinoembryonic antigen (CEA), a marker for tumor activity, was significantly elevated at 480 nanograms per milliliter (ng/mL). A month later, he started chemotherapy. By then, his CEA levels had risen to 1,498 ng/mL.

By the time Mr. Alderson started treatment, his colon cancer had metastasized and spread to his liver, where he had 25 tumors. “I was off their charts,” Mr. Alderson said in an interview with The Cancer Box, a cancer diagnosis blog. Due to concerns about COVID-19 and the ongoing pandemic, Mr. Alderson started looking into preventative medication and found ivermectin. Further research showed that the drug could likely enhance the effectiveness of his chemotherapy and radiation therapy and was relatively safe. In February 2021, he began taking ivermectin. Ten days later, his CEA levels had dropped to 184 ng/mL.

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Mr. Alderson went on to live another two years before succumbing to liver failure due to the progression of his three remaining liver tumors.

“His life was definitely extended,” Mrs. Alderson said, reflecting on Mr. Alderson’s cancer journey.

She attributes Mr. Alderson’s survival beyond his prognosis to his success with ivermectin and the chemotherapy drug fluorouracil. “Ivermectin was instrumental,” she said.

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“FDA can inform, but it has identified no authority allowing it to recommend consumers ‘stop’ taking medicine,” U.S. Circuit Judge Don Willett, appointed under President Trump, wrote for the court. The appeals court remanded the case back to the district court.

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