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Message

re: 11x increase in shingles after shingles shot for those 65 & older.

Posted on 3/29/26 at 12:15 pm to
Posted by TigerDoc
Texas
Member since Apr 2004
11847 posts
Posted on 3/29/26 at 12:15 pm to
quote:

That’s intentional


I will agree with you when you start doing things like investigate the credibility of Kirsch and his subtweeter, but that's another level of analysis that I've found is harder to get people to see here, so I start with the science communication itself, but you're not wrong.

What are the credibility problems you see?
Posted by Stat M Repairman
Member since Jun 2023
2810 posts
Posted on 3/29/26 at 12:19 pm to
People couldn't appreciate that the risk of the solution can't outghtweigh the problem itself.

Every third commercial on tv now is trying to convince people to take some drug.

It's a mind virus that's irresistible to some segment of the population.
Posted by TigerDoc
Texas
Member since Apr 2004
11847 posts
Posted on 3/29/26 at 12:22 pm to
No, the population is aging. Shingles is a disease of aging. As we get older we’ll get more shingles until the cohort of people who’ve been vaccinated for varicella age into being in the at-risk age group after which it will fall (it will also fall because the age population distribution will shift back I think but I’m a little less confident about that), but the other factor is whether we continue to even vaccinate kids for chickenpox at all. If anti-vaccine attitudes continued to rise, older adults might continue to get high rates of shingles in ongoing away. It’s really our choice as a society because this actually possibly could become a preventable disease. Would be good right?
Posted by TigerDoc
Texas
Member since Apr 2004
11847 posts
Posted on 3/29/26 at 12:24 pm to
I agree with you about pharmaceutical advertising. we would be better off with less of it. But we should evaluate this independently of the safety and effectiveness of the interventions themselves.
Posted by Stat M Repairman
Member since Jun 2023
2810 posts
Posted on 3/29/26 at 12:36 pm to
Big-Pharma advertising has done its best to ruin live sports though.

I'd like to chill and watch a game without having to be reminded of deadly afflictions at every commercial break.

Mind blowing that they can bribe the mass media right in front of our face with no recourse.

America is the only country that allows this insanity.
Posted by the808bass
The Lou
Member since Oct 2012
128778 posts
Posted on 3/29/26 at 12:38 pm to
quote:

Should we go into why that's better than OP?


No. I’m not arguing for the OP. I’m arguing for exactly the kind of education you’re giving your patients.
Posted by Zach
Gizmonic Institute
Member since May 2005
117564 posts
Posted on 3/29/26 at 12:41 pm to
quote:

Your nurse must be an a-hole. The only shots I’ve had that hurt was steroids when it started burning and the dumb bitch at CVS who gave me my covid shot(damn government contractor mandates)

There is a skill difference. I have to get a blood test after my yearly physical. Last year it hurt like hell. This year the girl said 'OK, that's it.' I was waiting for the needle and she was already finished drawing. I never felt it.
Posted by LSUbest
Coastal Plain
Member since Aug 2007
16390 posts
Posted on 3/29/26 at 12:43 pm to
quote:

Every third commercial on tv now is trying to convince people to take some drug.


Growing up I was warned by everyone to watch out for the pusher. We had all kinds of dope around the hood, but no one ever tried to push it. The pusher was some non existent bogeyman made up by people that knew nothing about dope or dealers.

Now I know who the pushers are.
Posted by FutureMikeVIII
Houston
Member since Sep 2011
1777 posts
Posted on 3/29/26 at 12:43 pm to
quote:

What are the credibility problems you see?


I mean, OP left out the transient aspect in his title. That’s probably not intentional though, just a word he didn’t understand, but it’s pretty crucial.

Your tack is definitely more effective than mine. I just get annoyed by the tired anti-vax tropes.
Posted by onmymedicalgrind
Nunya
Member since Dec 2012
12182 posts
Posted on 3/29/26 at 12:46 pm to
quote:

11x increase in the 21 days following first dose to accomplish a reduction of 1 case of shingles per 125 patients vaccinated. Imma pass.

In order to make an informed decision, wouldn’t you need to know the risk of contracting shingles during a random 21 day interval?
Posted by Auburn1968
NYC
Member since Mar 2019
26482 posts
Posted on 3/29/26 at 12:56 pm to
quote:

quote:
I wonder if the shot might boost the immune response of someone who currently suffers from Shingles.


Good question. The shingles shot isn’t used to treat an active case -


If it might help boost an immune response and there was no real risk of harm, is it worth a try...
Posted by the808bass
The Lou
Member since Oct 2012
128778 posts
Posted on 3/29/26 at 1:08 pm to
quote:

In order to make an informed decision, wouldn’t you need to know the risk of contracting shingles during a random 21 day interval?


It’s statistically zero.
Posted by ruzil
WNC
Member since Feb 2012
18378 posts
Posted on 3/29/26 at 1:18 pm to
quote:

The drug in question wasn't available widely until 2018 (here in USA) It was around 18-19 that I went to the doctor, before all went to hell and they didn't see folks for a few years in person.


quote:

In the U.S., the first shingles vaccine became available in 2006. That vaccine was Zostavax, which the FDA licensed in 2006. The newer shingles vaccine, Shingrix, was approved later on October 20, 2017 and is the one currently used in the U.S.


I guess she didn't trust the original version.
Posted by LSUbest
Coastal Plain
Member since Aug 2007
16390 posts
Posted on 3/29/26 at 1:22 pm to
quote:

If it might help boost an immune response and there was no real risk of harm, is it worth a try...



quote:

Zostavax, a live shingles vaccine discontinued in 2020, has been linked in lawsuits and reports to serious adverse events including contracting the shingles virus itself, blindness, hearing loss, paralysis (Bell's palsy), neurological disorders like Guillain-Barre Syndrome (GBS), congestive heart failure, stroke, and death.
quote:

Guillain-Barré syndrome (GBS) is a rare autoimmune disorder where the immune system attacks peripheral nerves, often triggered by a preceding viral or bacterial infection. It causes rapid onset tingling, muscle weakness, and potential paralysis, frequently requiring emergency care and long-term rehabilitation, though most patients eventually recover.
Posted by the808bass
The Lou
Member since Oct 2012
128778 posts
Posted on 3/29/26 at 2:13 pm to
quote:

serious adverse events including contracting the shingles virus itself, blindness, hearing loss, paralysis (Bell's palsy), neurological disorders like Guillain-Barre Syndrome (GBS), congestive heart failure, stroke, and death.


I know that doctors were telling people all about those adverse events before it was pulled. Right?
Posted by Riverside
Member since Jul 2022
10673 posts
Posted on 3/29/26 at 2:16 pm to
I had shingles and it’s awful. I can only imagine how bad it would be for an old person. Definitely take the vaccine if you can. Just my .2 cents.
Posted by dgnx6
Member since Feb 2006
89765 posts
Posted on 3/29/26 at 2:20 pm to
Don't even know the long term affects of chicken pox vaccines. They didn't give those to us when I was younger and I'm not even 40 yet.




Posted by SouthEasternKaiju
SouthEast... you figure it out
Member since Aug 2021
47076 posts
Posted on 3/29/26 at 2:24 pm to
Or maybe she was just still in HS…
Posted by LSUbest
Coastal Plain
Member since Aug 2007
16390 posts
Posted on 3/29/26 at 2:35 pm to
quote:

I know that doctors were telling people all about those adverse events before it was pulled. Right?


You know that.
Posted by Ace Midnight
Between sanity and madness
Member since Dec 2006
95632 posts
Posted on 3/29/26 at 2:50 pm to
quote:

Seems like a reasonable thing to discuss openly rather than just framing it one way or the other. Where OP goes wrong is it lacks context and it ends up being misleading.


Yeah, I was generally against the COVID vaccine mandates and think the childhood schedule should be reduced and decompressed.

However, I also believe that the key childhood vaccines have been a literal miracle for children since the late 1940s, early 1950s and many young folks did not go through polio epidemics or pertussis, or measles, etc., so they are skeptical about vaccines, not seeing the world without them.

I watched my father-in-law essentially die of shingles. He was going through chemo for multiple myeloma over a decade after he had beaten kidney cancer. The chemo was going well, but he developed shingles. The ongoing treatment for the myeloma was effectively suspended, then restarted and he passed from complications from chemo - while still in agony from PHN.

Hard pass. I got the 2 doses of Shingrix last year. No regrets. The consensus is that the effects of the second shot are worse, but it wasn't that bad. I updated my Tdap the same time as the first shot and the effects of that double were worse than the second Shingrix.

Shingles as an older person, especially with the risk of PHN, is...no...joke.
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