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Started By
Message
re: FDA approves Mounjaro for weightloss- called Zepbound
Posted on 11/8/23 at 3:47 pm to GBPackTigers
Posted on 11/8/23 at 3:47 pm to GBPackTigers
It fricks with your GI tract.
Slows down digestion so you’re not feeling hungry as you normally would.
This, and folks abusing it, is why there are people dying from bowel obstructions because of it.
Slows down digestion so you’re not feeling hungry as you normally would.
This, and folks abusing it, is why there are people dying from bowel obstructions because of it.
1
Posted on 11/8/23 at 3:47 pm to lsu777
This quote by the Eli Lilly CEO:
“Before Prozac, patients suffering from depression were essentially told they seem sad, and to try to be a little bit happier, as if they weren’t working hard enough to be happy,” Ricks said. “Today we’re at the beginning of another exciting time in Lilly’s long and distinguished history of making innovative medicines with the approval of Zepbound.”
“Before Prozac, patients suffering from depression were essentially told they seem sad, and to try to be a little bit happier, as if they weren’t working hard enough to be happy,” Ricks said. “Today we’re at the beginning of another exciting time in Lilly’s long and distinguished history of making innovative medicines with the approval of Zepbound.”
Posted on 11/8/23 at 4:05 pm to letsgobowling110599
quote:
Exactly. Not even the best weight loss drug will change a person's diet and lifestyle; it's on the person to make the change. This is a short cut, that's all it is. And it's not going to permanently fix the problem.
People that have no clue how this works and what effects this has love to opine.
Not only does it reduce appetite through indigestion, it impacts dopamine, decreasing addiction like symptoms that exist due to dopamine signaling.
The GLP-1 Agonist drugs have almost 2 decades worth of research up to this point, and the more we find out, the better they seem to affect the majority of people that could use them.
Posted on 11/8/23 at 4:07 pm to redstick13
quote:
would put me at 135 lbs at a height of 6’1”.
Then why would you be taking prescription weight loss drugs?
Oh… you just wanted to brag on your current weight and exercise regimen.
Posted on 11/8/23 at 4:12 pm to East Coast Band
quote:
AD 2043:
"Did you or a loved one take Zepbound for weight loss? You may be entitled to compensation...."
Write it down.
Posted on 11/8/23 at 4:40 pm to soccer dad
quote:
DNP has nothing to do with appetite suppression - it affects the metabolism of glucose at the cellular
Ummm I know…hence why I said the exact same thing
Posted on 11/8/23 at 6:20 pm to HempHead
quote:
Got a buddy on Zempys that still eats like a fricking horse and he's lost 30lbs. Figured it was something along the same lines - probably shouldn't speak out of ingnorance.
Depending on the medication, eating a lot on certain drugs will have an impact on their bowels.
While they may eat a lot, their body doesn’t absorb the calories as much and will head down the drain as liquid into their large intestines leading to loose stools.
If anyone remembers the Olestra Chips, that is what Ozempic does to your body. That is why you have to watch what you eat when you are on it.
Voice of experience here talking as a Semaglutide user.
This post was edited on 11/8/23 at 6:44 pm
Posted on 11/8/23 at 6:22 pm to lsu777
There’s been a shortage apparently. So I guess this means that the diabetics that actually need the drug will not be able to get it?
Posted on 11/8/23 at 6:28 pm to HempHead
quote:
Nothing in life is free. I'd be scared shitless of a pill that makes me lose weight without a corresponding lack of appetite.
It is an injection not a pill, but it does decrease appetite. It basically causes insulin to work better and it actually causes slowing of gastric emptying. So it is biologically an ideal medication for decreasing appetite and the especially feeling extremely hungry or cravings for sweets as you don't bottom out your glucose.
This is totally different mechanism of action than the amphetamine derived appetite suppression, for instance.
Posted on 11/8/23 at 6:52 pm to lsu777
quote:
until they banned peptides at start of the month, i also suggest people that take this start a BPC/GHRH/GHRP protocol to help with loose skin, stomach issues, overall health and anti aging.
I missed this. what got banned? Is there a link for more details if too much to get into here?
Thanks
Posted on 11/8/23 at 6:55 pm to lsu777
Been riding that NVO and LLY ride all year. Pfizer is next.
Posted on 11/8/23 at 6:57 pm to dewster
quote:
There’s been a shortage apparently. So I guess this means that the diabetics that actually need the drug will not be able to get it?
This is true. Some countries have banned any use outside of diabetes treatment. But both companies are ramping up production.
Posted on 11/8/23 at 7:01 pm to GBPackTigers
quote:
I know someone who got on this drug
Hate to hear that! Do you know if they were taking Mounjaro (from Eli Lily, prescribed by doc) or taking a compounded formula from a weight loss clinic or online doctor?
The most concerning thing is that many people are using the compounded injections which haven’t been tested and aren’t as effective. And Im pretty sure many of them are the same people who are too afraid to take a vaccine.
I’m not doubting your friend’s experience, but that is very rare. Most people have very good results with few side effects. Several people that I know have improved their overall health (not just weight) and been able to come off of several meds (for pain, diabetes, inflammation, etc).
Posted on 11/8/23 at 7:11 pm to paperwasp
quote:
But there hasn't been ten years of trials using non-diabetics.
People have been using them off label for weight loss since Byetta hit the market in around 2005.
I've seen numerous patients lose enough weight to cure their diabetes and eliminate other expensive medicines. Blood sugar better, lipids better, HTN better, mood improved, more active. It takes lifestyle changes, but the medicine helps by blunting the mechanism that spurs our hunger.
Posted on 11/8/23 at 7:15 pm to GBPackTigers
quote:
I know someone who got on this drug and lost weight but it has caused everything else about her health to go all out of control. The prescribing doctor has taken her off and still can’t normalize things.
I've never seen that and I've been using this drug class since 2005 or so. Sounds like they have other issues that haven't been diagnosed. Can certainly set off subclinical gallbladder issues. Sounds like they need a new doctor.
And was it from a pharmacy or some mail order or compounded bullshite? That's a whole different animal.
Posted on 11/8/23 at 7:19 pm to Geauxld Finger
quote:
It fricks with your GI tract.
Slows down digestion so you’re not feeling hungry as you normally would.
This, and folks abusing it, is why there are people dying from bowel obstructions because of it.
Well if you misuse it and have negligent oversight or no oversight of it's use, then you can certainly have issues. This is true of anything. That's why I screen my patients properly, use it as indicated and warn/monitor them for signs or symptoms that may indicate an issue before it becomes severe.
ETA-and it's a pain in the arse for me to write. Thanks to the rampant off label use, we now have to do a PA for damn near everyone on it. It would be much easier for me to not write them.
This post was edited on 11/8/23 at 7:21 pm
Posted on 11/8/23 at 7:26 pm to SmackoverHawg
quote:
That's why I screen my patients properly,
Isn't this the key to prescribing meds?
My sister is a diabetic that has just been prescribed Mounjaro in lieu of Trulicity. She was also on metformin, but her doc said that prolonged use of this could damage her kidneys. Her A1C also went up while on metformin.
So, she will begin the mounjaro and monitor A1C. I don't know who in the hell to trust anymore.
Posted on 11/8/23 at 7:29 pm to GBPackTigers
quote:
has caused everything else about her health to go all out of control
Like what?
Posted on 11/8/23 at 7:31 pm to lsu777
Another wonder drug!
What could go wrong?
What could go wrong?
Posted on 11/8/23 at 7:56 pm to canyon
quote:
Isn't this the key to prescribing meds?
Yes, but many are running weight loss clinics. Mainly NP's but plenty of physicians as well.
There are no "miracle meds". There's always a price to pay. Natural is the best way. It's up to the patient and provider to decide at what point the benefits outweigh risk.
quote:
I don't know who in the hell to trust anymore.
No one explicitly. Trust but verify. Do your own research and don't be afraid to ask questions. A good doctor doesn't mind answering reasonable questions.
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