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New cholesterol treatment can cut levels by 69% after one dose

Posted on 7/8/25 at 11:19 am
Posted by Will Cover
Davidson, NC
Member since Mar 2007
39854 posts
Posted on 7/8/25 at 11:19 am
quote:

A single shot of a new drug can lower cholesterol levels by up to 69 per cent, according to the initial results of a clinical trial that has not yet been peer reviewed.

The treatment, called VERVE-102, could transform the future of heart attack prevention by dramatically lowering the amount of LDL cholesterol – the so-called ‘bad’ cholesterol – with just a single injection.


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Posted by Marciano1
Marksville, LA
Member since Jun 2009
19748 posts
Posted on 7/8/25 at 11:29 am to
My total was 244 last summer. Got it to 238 in the fall and now 212 by eating better, specifically including olive oil and avocados several times per week.

LDL went from 160 -> 149 -> 139 in the same time frame.

It's slow progress but going in the right direction. Also should note I really cut back on rice/gravy and alcohol.
Posted by Lakeboy7
New Orleans
Member since Jul 2011
27994 posts
Posted on 7/8/25 at 11:41 am to
But what about the muh dementia (statins don’t cause dementia)?
Posted by lsugerberbaby
baton rouge
Member since Mar 2008
3026 posts
Posted on 7/8/25 at 12:24 pm to
quote:

by eating better


This is what I like to see. Big props and congrats!
Posted by lsu777
Lake Charles
Member since Jan 2004
36517 posts
Posted on 7/8/25 at 12:39 pm to
i think its good but ill wait a half decade at least before ever considering it.
Posted by Motorboat
At the camp
Member since Oct 2007
23887 posts
Posted on 7/8/25 at 1:40 pm to
I still cannot believe that people still buy into this cholesterol myth
Posted by guedeaux
Member since Jan 2008
13826 posts
Posted on 7/9/25 at 7:44 am to
quote:

I still cannot believe that people still buy into this cholesterol myth


And what is the myth?
Posted by Marciano1
Marksville, LA
Member since Jun 2009
19748 posts
Posted on 7/9/25 at 8:14 am to
quote:

cholesterol myth
Cholesterol is not a myth. What you're referring to is the debate on how much it affects heart health and what exactly impacts the levels.
Posted by Uncle JackD
Member since Nov 2007
59424 posts
Posted on 7/9/25 at 9:10 am to
The cholesterol alone isn’t the issue majority of the time. It’s the things that accompany it such had elevated triglycerides, insulin resistance, HTN, elevated CRP, etc… Which is usually the case with your typical South LA person.

But it still doesn’t hurt to keep LDL down. I take ezetimibe just to lower mine a little for peace of mind.
Posted by Motorboat
At the camp
Member since Oct 2007
23887 posts
Posted on 7/9/25 at 9:47 am to
That high cholesterol is bad and we need statins or meds to correct.
Posted by chryso
Baton Rouge
Member since Jul 2008
13504 posts
Posted on 7/9/25 at 10:12 am to
quote:

That high cholesterol is bad and we need statins or meds to correct.


There are so many conflicting opinions on this one that I don't know what to believe.
Posted by PrezCock
Florida
Member since Sep 2019
857 posts
Posted on 7/9/25 at 10:24 am to
FWIW looking into this whole mess my take is this. Cholesterol is not bad, it's actually vital for many physiological functions. In the case of heart disease, cholesterol is better used as a biomarker for circulatory inflammation. The body's response to that inflammation is releasing cholesterol. Fighting cholesterol is not the answer. Fighting what is causing the circulatory inflammation is, and mainly that is a terrible diet filled with sugars (carbohydrates).

The FDA food pyramid is BS. 60%+ of carbohydrates in American's diets is what's killing people, not cholesterol. Cholesterol is trying to fight that garbage diet.

Again, my two cents, take it for what it's worth.
Posted by Uncle JackD
Member since Nov 2007
59424 posts
Posted on 7/9/25 at 10:28 am to
quote:

Fighting cholesterol is not the answer. Fighting what is causing the circulatory inflammation is, and mainly that is a terrible diet filled with sugars (carbohydrates).
Correct. Triglycerides & A1C are a better indicator. But like I said, the majority of people either dyslipidemia in our area aren’t just seeing elevated LDL, it’s usually a combo of multiple markers. LDL is just the one they choose to treat instead of the root cause.

That being said, I don’t think it’s a bad thing to keep LDL in the mid range I was upper 80s-90 and got on Zetia to drop it a tad. Triglycerides 39
This post was edited on 7/9/25 at 10:33 am
Posted by Motorboat
At the camp
Member since Oct 2007
23887 posts
Posted on 7/9/25 at 11:20 am to
I would believe my doctors but they lost my trust after Covid.
Posted by Lakeboy7
New Orleans
Member since Jul 2011
27994 posts
Posted on 7/10/25 at 9:27 am to
quote:

I would believe my doctors but they lost my trust after Covid.


I bet if you get cancer or need a heart surgery your arse runs to the doctors office.

Dont let your politics kill you.

You know what, yes let your politics kill you.
Posted by Reubaltaich
A nation under duress
Member since Jun 2006
5336 posts
Posted on 7/11/25 at 3:58 am to
Eating a better diet works miracles for most folks.

Cauliflower, broccoli, Brussel sprouts, almonds, avocados, blue berries, walnuts, fresh fish...omega3 fish oil supplements.

Cutting back on sugar, greasy fried foods, sodas, sports and energy drinks, ultra processed 'foods'...

Moderate exercise
Posted by Reubaltaich
A nation under duress
Member since Jun 2006
5336 posts
Posted on 7/11/25 at 4:25 am to
quote:

But what about the muh dementia (statins don’t cause dementia)?


Statins do lower cholesterol but at what cost?

Look at this way, cholesterol is produced in the liver. So what is the side effect on our livers?

Our brains consist of about 25% cholesterol. So if statins are reducing cholesterol, what is its effect on the human brain?

I have a yearly wellness exam, blood test showed HDLs, Tri's were normal. LDLs were a tad high.
A cardio doc decided I need to be on statins, 10mg per day.

That mess made every muscle and joint in my body feel like I had been hit by a freight train. I had brain fog too and was hard to concentrate.
I quit taking them and it took about 3 weeks for that stuff to clear out of my body.

Statins are the largest prescribed drug in the world. Big pharma is making mega OT $$$ from their sale.

More and more evidence is coming in on statins.

Do your own research and make your choices.
Posted by Shepherd88
Member since Dec 2013
4874 posts
Posted on 7/12/25 at 5:41 pm to
Bingo, cholesterol is just the vehicle of delivery.

It doesn’t fix the road which is caused by inflammation (sugar). If the road is broke the vehicle will wreck and cause a traffic jam. If the road is fine then you have an efficient delivery system and no reason to mess with it.
Posted by Raoul Stimulato
Hale Bopp Comet
Member since Sep 2022
1983 posts
Posted on 7/13/25 at 10:11 am to
The hard truth for most of us to accept

Is that if you eat clean and cut out alcohol, sugars, processed foods, 98% of health issues will abscond with a quickness.

But it ain’t easy. Especially in today’s world w easy access to just about everything.

This post was edited on 7/13/25 at 10:12 am
Posted by Reubaltaich
A nation under duress
Member since Jun 2006
5336 posts
Posted on 7/14/25 at 5:47 am to
Way too often, those in the medical field just want to throw a pill at the issue and not at least advise patients on preventative measures such as a healthy eating, moderate exercise...

Anywho, I have posted this on statins before. Its a fairly long read:

quote:

•There is a widespread belief that elevated cholesterol is the “cause” of cardiovascular disease. However, a large body of evidence shows that there is no association between the two and that lower cholesterol significantly increases one’s risk of death.

•An alternative model (which the medical industry buried) proposes that the blood clots the body uses to heal arterial damage, once healed, create the characteristic atherosclerotic lesions associated with heart disease. The evidence for this model, in turn, is much stronger than the cholesterol hypothesis and provides many important insights for treating heart disease.

•The primary approach to treating heart disease is to prescribe cholesterol lowering statin drugs (to the point, over a trillion dollars have now been spent on them). Unfortunately, the benefits of these highly toxic drugs are minuscule (e.g., at best taking them for years extends your life by a few days) and the harms are vast (statins are one of the most common pharmaceuticals that severely injure patients).




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