- My Forums
- Tiger Rant
- LSU Recruiting
- SEC Rant
- Saints Talk
- Pelicans Talk
- More Sports Board
- Fantasy Sports
- Golf Board
- Soccer Board
- O-T Lounge
- Tech Board
- Home/Garden Board
- Outdoor Board
- Health/Fitness Board
- Movie/TV Board
- Book Board
- Music Board
- Political Talk
- Money Talk
- Fark Board
- Gaming Board
- Travel Board
- Food/Drink Board
- Ticket Exchange
- TD Help Board
Customize My Forums- View All Forums
- Show Left Links
- Topic Sort Options
- Trending Topics
- Recent Topics
- Active Topics
Started By
Message
re: Weight loss drug (Semaglutide) cut major adverse cardiovascular events by 20 percent
Posted on 8/9/23 at 9:53 am to SWCBonfire
Posted on 8/9/23 at 9:53 am to SWCBonfire
quote:
I think the greater contributing food factor is the addition of fructose and/or sugar into everything. It was one thing to drink a Coke or Kool-aid and expect it to be filled with sugar, but when your bread, sandwich meat, and everything else has added sugars, all those excess carbs you get from everything go straight into making fat.
0
Posted on 8/9/23 at 9:56 am to X123F45
quote:
Except it will allow their stomach time to shrink, reduce inflammation.
That's still not going to teach them healthy eating/portion control. These things don't even stick for many people who have surgery to make their stomach smaller -- they are known to go right back to eating the same way.
I predict most people who go this route are either going to be on this drug forever or just regain the weight and end up back where they were
Posted on 8/9/23 at 10:06 am to BawtHouse
quote:
It’s the same thing. The difference is that society has accepted heart disease as a disease and heart disease doesn’t show on our outside. Obesity is a disease, but society as a whole has not accepted that it is a disease…yet.
Obesity is disease that is triggered by human conduct/ decisions. So is heart disease to some extent, but lesser. Obesity isn't something you catch, or that's beyond your control. There isn't an obesity virus that has caused obesity to spike out of control in the past several decades.
People who are on pharmaceuticals for obesity, heart, blood pressure, mood, attention, sleep (or multiple if not all of those) aren't living well. Doubly true for people who are middle aged and on those sorts of multi-drug cocktails. But the drug companies make bank, and all the TV ads are about "ask your doctor about. . ." when the person would be healthier and happier overall if they turned off the TV, exercised more, ate better, and slept well.
Posted on 8/9/23 at 10:17 am to SWCBonfire
quote:
I think the greater contributing food factor is the addition of fructose and/or sugar into everything. It was one thing to drink a Coke or Kool-aid and expect it to be filled with sugar, but when your bread, sandwich meat, and everything else has added sugars, all those excess carbs you get from everything go straight into making fat.
yet there are over a dozen studies that show once protein and calories are equated......where the rest of your calories come from do not matter in terms of losing body fat, atleast until well below 15%.
so your feelings mean shite.
Posted on 8/9/23 at 10:41 am to lsu777
quote:
yet there are over a dozen studies that show once protein and calories are equated......where the rest of your calories come from do not matter in terms of losing body fat, atleast until well below 15%.
so your feelings mean shite.
This is factually true but how does this contradict his point? Adding sugars doesn't make someone feel any more satiated so adding sugar to things like bread and sandwich meat (his examples) means you will have taken in more calories before you feel "full." This makes it harder for people to naturally regulate their eating based upon satiety and natural signaling, and instead they must put more mental work into counting calories.
Obviously the responsibility is still on the individual to not consume excess calories but people aren't putting in that mental effort, because since the dawn of time we've relied on natural signaling to tell us when to stop eating. Nobody says "this bread has 12% more calories than the old stuff due to added sugars so I'm going to cut off 1/8 of my sandwich and feel less full." They just eat the sandwich
This post was edited on 8/9/23 at 11:22 am
Posted on 8/9/23 at 10:45 am to lsu777
quote:
so your feelings mean shite.
Damn dude, can you show us on the doll where Semaglutide touched you?
Lighten up, Francis.
Posted on 8/9/23 at 10:48 am to tigerskin
Bunch of gross undisciplined fatties up in here
Posted on 8/9/23 at 10:49 am to lsu777
quote:
lsu777
Posted on 8/9/23 at 10:51 am to efrad
quote:
Adding sugars doesn't make someone feel any more satiated so adding sugar to things like bread and sandwich meat (his examples) means you will have taken in more calories before you feel "full." This makes it harder for people to naturally regulate their eating based upon satiety and natural signaling, and instead they must put more mental work into counting calories
Had this same realization recently after we ordered Dominos for the first time in a long time. 3 slices of a medium pizza and I wasn't starting to feel full at all. I probably could have finished the whole pizza and my brain wouldn't have sent the full signal even after eating 2000 calories.
Posted on 8/9/23 at 10:57 am to tigerfoot
quote:
Most of them look so damn weak it is hard to think it is a good thing
That has been my experience as well. Several I had not seen in a few months and when I did I thought they had cancer or something. It was startling.
One very good friend lost 40 lbs without doing any lifting or exercise at all. He went from looking strong to a washed up old man in the span of months.
Posted on 8/9/23 at 11:02 am to Cosmo
quote:
The negative side effects will come out in a few years
Nothing that works this well comes without a price
Except that it will be this year, at a conference and probably simultaneous publication. And there is a control group, so you get to have a direct comparison.
There may be a push by junk food/fast food lobby to negatively message because it is clear this class of drug is effective and helping insulin work more sufficiently and decreases the rate of gastric emptying which has lead to decreased over eating. It would be hard to imagine what potential long term effects would provide a negative benefit/risk ratio when looking at 20% drop in cardiovascular events, which can be fatal.
This is nothing like the COVID vaccine where from the start the general population was at very low risk and only the elderly or sick were at high risk, and the vaccine was rushed out without proper transparency to provide for a true informed consent. Public Health has a supposedly different mantra with regards to individual decision making. We as patients will have much more information about these GLP-1 agonists and we will have more choice in the matter, vs the mandates that forced us to get vaccinated if we had to travel or work, etc.
Yes, the price is decreased appetite, feeling full so you may not be able to eat that entire Burger with exlarge coke and fries. Some nausea, maybe vomiting or other GI issues that tend to get better with time and adjustments in better eating. This class of drugs is going to save lives and extend lifespans. But will cause some mild to moderate GI symptoms at times. Again, we get to decide though.
Posted on 8/9/23 at 11:07 am to SWCBonfire
quote:
Damn dude, can you show us on the doll where Semaglutide touched you?
Lighten up, Francis.
777 knows his stuff.
I am on 0.5mg subq weekly. My greatest benefit is the decrease in appetite. I am not hungry at breakfast, have a mid morning snack (beef jerky these days), drink a protein shake after my workout at lunch and a smaller than usual sized dinner. I am down about 7-8 pounds in the last month or so.
Posted on 8/9/23 at 11:12 am to TigerIron
quote:
People who are on pharmaceuticals for obesity, heart, blood pressure, mood, attention, sleep (or multiple if not all of those) aren't living well.
This is one of the most factually inaccurate statements in the history of this site, and that is saying a lot.
Which is ironic because it is followed by this last sentence..
quote:
when the person would be healthier and happier overall if they turned off the TV, exercised more, ate better, and slept well.
which is very true. But for many, many people, is not in itself sufficient to obtain objective health goals. Health is not the binary equation that is presented here. But you are of course free to believe what you want to believe.
Posted on 8/9/23 at 11:34 am to tigerskin
Where can I buy this. I'll try it
Posted on 8/9/23 at 11:48 am to efrad
quote:
In this thread you've said it's a hormonal imbalance and it's genetic, but when asked about why these hormonal imbalances exist now and not in our grandparents' time, you circle back to the food?
If we simply ate the healthier food our grandparents ate in the amounts our grandparents ate, would our "genetics" not revert back to the hormonal expression they did for our grandparents?
You're 100% spot on about eating the healthier foods. At face value that is a super simple explanation and if it applied to everyone equally, this would be an easy problem to solve.
What they are learning from these types of drugs is that hormones play a MASSIVE role in driving behaviors based around consumption of the shitty foods that have been continually been pointed to as the problem. You're not wrong but what you're missing is that everyone's body processes foods at different efficiency levels and that hormones make it extremely difficult for some people.
The other problem is that when I say "hormones" everyone has this visual of a 500lb large Marge stuffing her face with cheetos saying she has hormone issues. Let me paint a different picture for you. Let's assume for a second that you and your spouse have to go to a family counseling because you didn't have the same level of sex drive and it was causing issues. The counselor tell you - "well, if you just didn't want sex as much, this wouldn't be a problem." See how will power doesn't really work well for that scenario? Your body is telling you that you want sex ALL THE TIME... you're biologically driven to want to reproduce. It doesn't matter how much will power you have. You might substitute rubbing one out every night instead of going to pound town, but you'd still want it constantly.
BTW - the reason I know this is because I'm taking semaglutide right now and can tell you that the major benefit is the indifference between eating or not eating foods that used to be major drivers for me. Sugary stuff more than anything.
This post was edited on 8/9/23 at 11:54 am
Posted on 8/9/23 at 11:52 am to genuineLSUtiger
quote:
It’s the American way. Don’t work on yourself just pop a pill.
My last boss lost the genetics lottery. He was cursed with high cholesterol. The dude never ate a fried piece of anything and exercised regularly. Even with meds he had trouble keeping his cholesterol level under 350.
His brother who was a few years older died while jogging when he was like 55.
So yeah, sometimes people do work on themselves, and a pill on top of all that isn't enough.
Just some food for thought.
This post was edited on 8/9/23 at 11:53 am
Posted on 8/9/23 at 11:56 am to genuineLSUtiger
quote:
It’s the American way. Don’t work on yourself just pop a pill.
This POV is so fricked.
While I do agree that way too many don’t get the recommended weekly exercise goals, but come on.
I prescribe this to many people. And then is just the extra motivation people need to get healthy and start their weight loss.
I caution all of them that it may be nothing more than a fad diet, but if you use it as tool in your belt to achieve a healthy lifestyle, then that’s the end goal.
Posted on 8/9/23 at 11:58 am to efrad
quote:
This is factually true but how does this contradict his point? Adding sugars doesn't make someone feel any more satiated so adding sugar to things like bread and sandwich meat (his examples) means you will have taken in more calories before you feel "full." This makes it harder for people to naturally regulate their eating based upon satiety and natural signaling, and instead they must put more mental work into counting calories.
Obviously the responsibility is still on the individual to not consume excess calories but people aren't putting in that mental effort, because since the dawn of time we've relied on natural signaling to tell us when to stop eating. Nobody says "this bread has 12% more calories than the old stuff due to added sugars so I'm going to cut off 1/8 of my sandwich and feel less full." They just eat the sandwich
the assumption was he was saying carbs are the reason people are fat.
its quite the theme of the OT but its not true
quote:
Damn dude, can you show us on the doll where Semaglutide touched you?
Lighten up, Francis.
wasnt trying to be a dick and i dont take any glp-1s. i was just saying that carbs arent the reason we are fat as a country.
do we consume way too many...yep but its because as a country we have went from eating foods that are satiating to those that arent because they taste good and it causes our protein numbers to be low(big difference in Diet induced thermogenesis) and our calories to be way over maintenance.
but the problem isnt carbs itself, its the calories and lack of proteins
Posted on 8/9/23 at 12:03 pm to jose
quote:
This POV is so fricked. While I do agree that way too many don’t get the recommended weekly exercise goals, but come on. I prescribe this to many people. And then is just the extra motivation people need to get healthy and start their weight loss. I caution all of them that it may be nothing more than a fad diet, but if you use it as tool in your belt to achieve a healthy lifestyle, then that’s the end goal.
Keep sucking the big pharma dick
Posted on 8/9/23 at 12:06 pm to danilo
quote:
Keep sucking the big pharma dick
Please explain this for me?
Wouldn’t lowering the cardiovascular risk (OP thread title) save everyone more money in the long run?
Wouldn’t a decrease in overall BMI lower the healthcare burden by lowering A1cs, cholesterol levels, improve blood pressure numbers, improve arthritic joints?
This post was edited on 8/9/23 at 12:11 pm
Page 6 of 8
Popular
Back to top
Follow TigerDroppings for LSU Football News