- My Forums
- Tiger Rant
- LSU Recruiting
- SEC Rant
- Saints Talk
- Pelicans Talk
- More Sports Board
- Fantasy Sports
- Golf Board
- Soccer Board
- O-T Lounge
- Tech Board
- Home/Garden Board
- Outdoor Board
- Health/Fitness Board
- Movie/TV Board
- Book Board
- Music Board
- Political Talk
- Money Talk
- Fark Board
- Gaming Board
- Travel Board
- Food/Drink Board
- Ticket Exchange
- TD Help Board
Customize My Forums- View All Forums
- Show Left Links
- Topic Sort Options
- Trending Topics
- Recent Topics
- Active Topics
Started By
Message
Let's talk about angiotensin-converting enzyme 2 (ACE2) and COVID.
Posted on 3/13/20 at 10:00 am
Posted on 3/13/20 at 10:00 am
quote:
Researchers have used cryogenic electron microscopy to show that coronaviruses enter human cells through an interaction with angiotensin-converting enzyme 2 (ACE2).
quote:
OVID-19 has been shown to bind to ACE2 via the S protein on its surface.
LINK
So no ACE2 with COVID, no infection.
I'm pretty sure the ACE2 allele is much more prevalent in Asian populations versus African and European populations. Anyone have a source for these numbers?
The point is infection and fatality rates should be much different between ethnicity based on the prevalence of this enzyme within an ethnic population.
12
Posted on 3/13/20 at 10:01 am to GumboPot
quote:
The point is infection and fatality rates should be much different between ethnicity based on the prevalence of this enzyme within an ethnic population.
The party of science will call this racist
Posted on 3/13/20 at 10:02 am to GumboPot
Smoking and some drugs increase ACE2 expression, too
Posted on 3/13/20 at 10:03 am to Tiguar
Which drugs?
Posted on 3/13/20 at 10:04 am to Tiguar
quote:
Smoking and some drugs increase ACE2 expression, too
And it's being reported that smoking is a major risk factor.
Posted on 3/13/20 at 10:04 am to GumboPot
quote:
COVID
Wuhan
Posted on 3/13/20 at 10:05 am to GumboPot
quote:Care to explain why this is hitting Italy so hard?
I'm pretty sure the ACE2 allele is much more prevalent in Asian populations versus African and European population
Posted on 3/13/20 at 10:06 am to Tigahs24Seven
ACEi like lisinopril. Those patients are doing worse. Patients taking ARBs like losartan seem to do better since they actually block the receptor
Posted on 3/13/20 at 10:06 am to Asharad
quote:
Care to explain why this is hitting Italy so hard?
I thought of this question too. My quick non researched answer, open borders.
Posted on 3/13/20 at 10:08 am to Asharad
quote:
Care to explain why this is hitting Italy so hard?
Similar noodle consumption rates.
Posted on 3/13/20 at 10:08 am to GumboPot
I think they smoke a lot more than us too
Posted on 3/13/20 at 10:11 am to GumboPot
quote:
Care to explain why this is hitting Italy so hard?
quote:
Since the 1980s, Lombardy has become the destination of a large number of international migrants, insomuch that today more than a quarter of all foreign-born residents in Italy lives in this region. As of 2016, the Italian national institute of statistics (ISTAT) estimated that 1,139,430 foreign-born immigrants live in Lombardy, equal to 11.4% of the total population.
1.5% of the population of Milan are Chinese
Posted on 3/13/20 at 10:16 am to GumboPot
quote:
I'm pretty sure the ACE2 allele is much more prevalent in Asian populations versus African and European populations.
This really is interesting. Is it more prevalent in some Chinese than in Koreans?
Posted on 3/13/20 at 10:17 am to Asharad
Italy has highest % of elderly people of any country of the world-23% over 65.The average age of those who have died is 81.
Posted on 3/13/20 at 10:18 am to GumboPot
What is the breakdown on the USA of corona virus deaths (around 40 currently) based on:
-age
-sex
-ethnicity
-smoking
This would be good to know
-age
-sex
-ethnicity
-smoking
This would be good to know
Posted on 3/13/20 at 10:19 am to GumboPot
No one has no ACE-2.
Asians are more likely to have the genetic variant that allows for production of high numbers of ACE-2.
Not all Genes in the DNA get fully expressed, some do, and some genes can be completely off.
The environment is responsible for most of what the DNA coding will allow to be expressed.
Asians are more likely to have the genetic variant that allows for production of high numbers of ACE-2.
Not all Genes in the DNA get fully expressed, some do, and some genes can be completely off.
The environment is responsible for most of what the DNA coding will allow to be expressed.
Posted on 3/13/20 at 10:33 am to GumboPot
quote:
I'm pretty sure the ACE2 allele is much more prevalent in Asian populations versus African and European populations. Anyone have a source for these numbers?
Sounds like a good indicator that there was an uprising put to rest with this virus...
Posted on 3/13/20 at 10:34 am to GumboPot
I sold an ACE inhibitor as well as an ARB.
Racist?
Racist?
Posted on 3/13/20 at 10:37 am to crazyatthecamp
quote:
What is the breakdown on the USA of corona virus deaths (around 40 currently) based on:
-age
-sex
-ethnicity
-smoking
IDK.
quote:
This would be good to know
Yes it would. The more info the better. The run on TP would probably stop.
Posted on 3/13/20 at 10:39 am to Tiguar
Page 1 of 3
Popular
Back to top
Follow TigerDroppings for LSU Football News