What if you had your choice of COVID-19 vaccine?

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What if you had your choice of COVID-19 vaccine? Differences are small, but they do exist

If you get the choice, which COVID-19 vaccine should you choose?

For now, experts are clear: The best vaccine is the one about to go into your arm. But as the vaccine supply grows, Americans eventually might find someone asking, “Which vaccine do you want?”

The answer for most people will still be “Whatever’s available.”But there are differences that could play a role, though doctors are unanimous that all three currently authorized vaccines work extremely well to protect against severe disease, hospitalization and death.

A shot now is better than waiting for a different shot, said Dr. Kathryn Edwards, scientific director of the Vaccine Research Program at Vanderbilt University’s School of Medicine. It likely benefits the individual and society alike by lowering the overall spread of the disease.

Beyond that, there are small trade-offs when it comes to the current vaccines. In general, Pfizer-BioNTech and Moderna vaccines require two doses and are somewhat more effective. Johnson & Johnson requires one dose and is somewhat less likely to cause side effects.

J&J's “one and done” aspect is a selling point for many.


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