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HailHailtoMichigan!
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Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
quote:

(Reuters) - An experimental coronavirus vaccine developed by Inovio Pharmaceuticals Inc (INO.O) showed promise and was found to be safe in an early-stage human trial, the company said on Tuesday.

The vaccine, one of the 17 being tested in humans and part of the Trump administration's "Operation Warp Speed" program, induced "immune responses" in healthy volunteers, Inovio said.

Immune responses in the study were measured by the vaccine's ability to generate binding antibodies, or virus-neutralizing antibodies, and T-cell responses - considered the two most important metrics for a successful vaccine.

Based on preliminary data, the drug developer said 34 of the 36 volunteers, all aged between 18 and 50 years, showed overall immunological response rates and most of the 10 patients with side-effects experienced only redness at the site of the shot.




LINK
This post was edited on 6/30 at 11:09 am


Privateer 2007
UNO Fan
Member since Jan 2020
1249 posts

re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
It's seemingly good news.
But, we've had story after story about this.
I'll believe it when I see it.


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110
Shaun176
LSU Fan
Baton Rouge
Member since Aug 2008
1824 posts

re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
This Vaccine is in 3rd or 4th place now.

The Oxford and Moderna Vaccines have been tested on a couple thousand so far and have been safe and effective. Both will be in full stage 3 which means 10s of thousands in the trial within weeks and emergency approval in 6-8 weeks.

China has a vaccine that they are probably using political prisoners to test that they and the WHO will probably approve for emergency use by the end of July.

The chinese vaccine will mostly be used in developing countries in exchange for allegiance with China. It will put pressure on the CDC and the Europeans to approve the Oxford and Moderna vaccines.



notsince98
Missouri Fan
KC, MO
Member since Oct 2012
12326 posts

re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
Bypassing animal testing has shown to be disaster and ended up killing people before.

Here we go again....lessons never seem to be learned anymore.


Cosmo
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Member since Oct 2003
99932 posts

re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
quote:

Bypassing animal testing has shown to be disaster and ended up killing people before.


But more often turns out fine

Stop being a drama queen


Pepe Lepew
LSU Fan
Looney tuned .....
Member since Oct 2008
34256 posts

re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
Guessing I’ll be in jail sooner than expected, I ain’t taking that crap


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Sasquatch Smash
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Member since Nov 2007
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re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
quote:

But more often turns out fine

Stop being a drama queen



Same can be said for allowing an acute respiratory illness to run its course.


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40
notsince98
Missouri Fan
KC, MO
Member since Oct 2012
12326 posts

re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
quote:

But more often turns out fine

Stop being a drama queen


if it saves one life, shouldn't proper testing protocols be followed? There are signs this same hyper immune response responsible for killing folks before is happening again with this vaccine.

Educate yourself.


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Shaun176
LSU Fan
Baton Rouge
Member since Aug 2008
1824 posts

re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
quote:

Bypassing animal testing has shown to be disaster and ended up killing people before


Moderna and Oxford both animal tested while they were doing phase 1 testing.



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the mighty weez
New Orleans Saints Fan
Member since Nov 2018
46 posts

re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
quote:

Bypassing animal testing has shown to be disaster and ended up killing people before.


They are animal testing...

quote:

In addition to positive interim Phase 1 data, INO-4800 has been shown to protect mice in SARS-CoV-2 viral challenge studies, where vaccination with INO-4800 prevented viral replication in the lungs of animals challenged with SARS-CoV-2. Moreover, INO-4800 is currently being tested in a ferret challenge model as well as in NHP challenge studies as part of Operation Warp Speed.

quote:

INO-4800 has been selected to participate in a non-human primate (NHP) challenge study as part of the U.S. government's Operation Warp Speed


Inovio Press Release


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notsince98
Missouri Fan
KC, MO
Member since Oct 2012
12326 posts

re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
Ferretts are the appropriate animal testing for respiratory diseases, not mice.

Are they reclassifying this now?

EDIT: I see they are doing ferretts too. That is good. Now they just need to do safety studies (they wont) and everyone will be happy and verify the hyper immune reaction is not happening.
This post was edited on 6/30 at 12:29 pm


Chitown_Badger
Wisconsin Fan
A one drink walk from Wrigley
Member since May 2013
15065 posts

re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
Brother bought it around $12 a share. Up over $28 now.


Fun Bunch
New Orleans Pelicans Fan
New Orleans
Member since May 2008
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re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
They are testing ferrets.


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Chitown_Badger
Wisconsin Fan
A one drink walk from Wrigley
Member since May 2013
15065 posts

re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
quote:

Now they just need to do safety studies (they wont) and everyone will be happy


You even phase I trials baw? How do you think they're including this line if they're not tracking safety?

quote:

was found to be safe in an early-stage human trial, the company said on Tuesday.


There's a couple things you want can test in clinical trials...safety, dosing, efficacy. Phase I is safety.
This post was edited on 6/30 at 12:34 pm


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OysterPoBoy
LSU Fan
City of St. George
Member since Jul 2013
19506 posts
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re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
If you think I’m gonna let the government inject me with a “vaccine” in the middle of the 5G rollout you have got another thing coming.


LSURussian
LSU Fan
9 acres of paradise in Baton Rouge
Member since Feb 2005
120992 posts
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re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
quote:

Bypassing animal testing has shown to be disaster and ended up killing people before.

Only in a limited number of cases. Why the drama, Queen?


escatawpabuckeye
Ohio State Fan
Member since Jan 2013
611 posts
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re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
Good summary


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Capt ST
Army Fan
Middle of the Mall
Member since Aug 2011
9431 posts

re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
If this was good news INO stock wouldn't have fallen 20% today.


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Chitown_Badger
Wisconsin Fan
A one drink walk from Wrigley
Member since May 2013
15065 posts

re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
quote:

If you think I’m gonna let the government inject me with a “vaccine” in the middle of the 5G rollout you have got another thing coming.


Huh?


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notsince98
Missouri Fan
KC, MO
Member since Oct 2012
12326 posts

re: Reuters: COVID-19 vaccine candidate shows promise in small early-stage trial
quote:

Only in a limited number of cases. Why the drama, Queen?


admitting said point is absolutely true and then calling it drama?

Should we go through this and analyze it with logic and reason or are you just going to admit you are resorting to personal attacks since you cant refute the facts?


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