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Question about the COVID mRNA vaccine.

Posted on 3/18/21 at 12:19 pm
Posted by GumboPot
Member since Mar 2009
118835 posts
Posted on 3/18/21 at 12:19 pm
Mature mRNA (from DNA) in our cell cytoplasm takes amino acids and arranges them into a proteins. Those proteins are building blocks of who we are as human animals.

If the mRNA COVID vaccine is making proteins to mimic the protein structure of COVID why would our immune system see COVID as a foreign body?

Seems counter intuitive.
Posted by Mingo Was His NameO
Brooklyn
Member since Mar 2016
25455 posts
Posted on 3/18/21 at 12:20 pm to
quote:

Mature mRNA (from DNA) in our cell cytoplasm takes amino acids and arranges them into a proteins


99.99% of OTers won't get past this sentence
Posted by Jim Rockford
Member since May 2011
98188 posts
Posted on 3/18/21 at 12:22 pm to
All I know is I'm really enjoying this 5G microchip.
Posted by Slagathor
Makin' jokes about your teeny tiny
Member since Jul 2007
37811 posts
Posted on 3/18/21 at 12:23 pm to
quote:

Seems counter intuitive.




aw shite, now we gotta throw all this research out
Posted by SloaneRanger
Upper Hurstville
Member since Jan 2014
7737 posts
Posted on 3/18/21 at 12:23 pm to
What, no "Sir this is a Wendy's" replies yet?
Posted by Lawyered
The Sip
Member since Oct 2016
29316 posts
Posted on 3/18/21 at 12:24 pm to
The mitochondria is the powerhouse of the cell
Posted by TDsngumbo
Alpha Silverfox
Member since Oct 2011
41623 posts
Posted on 3/18/21 at 12:24 pm to
I'm typing this response with all 17 of my fingers.
Posted by DWaginHTown
Houston, TX
Member since Jan 2006
9860 posts
Posted on 3/18/21 at 12:25 pm to
quote:

All I know is I'm really enjoying this 5G microchip.


Are you getting better cell reception with that?
Posted by HempHead
Big Sky Country
Member since Mar 2011
55486 posts
Posted on 3/18/21 at 12:25 pm to
quote:

If the mRNA COVID vaccine is making proteins to mimic the protein structure of COVID why would our immune system see COVID as a foreign body?



Posted by GRTiger
On a roof eating alligator pie
Member since Dec 2008
63031 posts
Posted on 3/18/21 at 12:27 pm to
I've accepted that the technology does what it says it does, but it's a good question for people who don't fully understand how it works (which is almost everyone.)

Of course posting this on the OT will only yield sarcasm from people who also don't know the answer but see any attempt to educate yourself as an affront to the treatment itself.
Posted by medtiger
Member since Sep 2003
21664 posts
Posted on 3/18/21 at 12:28 pm to
Because the mRNA is coding a protein that is foreign to the human body...the spike protein of the coronavirus.

ETA: from the cdc:

quote:

mRNA vaccines contain material from the virus that causes COVID-19 that gives our cells instructions for how to make a harmless protein that is unique to the virus. After our cells make copies of the protein, they destroy the genetic material from the vaccine. Our bodies recognize that the protein should not be there and build T-lymphocytes and B-lymphocytes that will remember how to fight the virus that causes COVID-19 if we are infected in the future.
This post was edited on 3/18/21 at 12:30 pm
Posted by GumboPot
Member since Mar 2009
118835 posts
Posted on 3/18/21 at 12:28 pm to


God, I miss Farley.
Posted by Jake88
Member since Apr 2005
68279 posts
Posted on 3/18/21 at 12:28 pm to
Because the S protein is foreign to our body even though the amino acids that make it are used in all sorts of protein structures in our bodies too.
Posted by CelticDog
Member since Apr 2015
42867 posts
Posted on 3/18/21 at 12:34 pm to
cdc says

quote:

COVID-19 mRNA vaccines give instructions for our cells to make a harmless piece of what is called the “spike protein.” The spike protein is found on the surface of the virus that causes COVID-19.

COVID-19 mRNA vaccines are given in the upper arm muscle. Once the instructions (mRNA) are inside the immune cells, the cells use them to make the protein piece. After the protein piece is made, the cell breaks down the instructions and gets rid of them.

Next, the cell displays the protein piece on its surface. Our immune systems recognize that the protein doesn’t belong there and begin building an immune response and making antibodies, like what happens in natural infection against COVID-19.

At the end of the process, our bodies have learned how to protect against future infection. "


Posted by GumboPot
Member since Mar 2009
118835 posts
Posted on 3/18/21 at 12:34 pm to
quote:

Because the mRNA is coding a protein that is foreign to the human body...the spike protein of the coronavirus.


Wouldn’t your immune system just see the vaccine mRNA as part of body and ignore it as self and ignore any proteins assembled from it?

Also, how does the vaccine mRNA get into the cell before its consumed by your immune system? Afterall it’s a foreign agent.
Posted by JDPndahizzy
JDP
Member since Nov 2013
6446 posts
Posted on 3/18/21 at 12:35 pm to
quote:

mitochondria


I think I had a case of that in high-school
Posted by TigerFred
Feeding hamsters
Member since Aug 2003
27174 posts
Posted on 3/18/21 at 12:36 pm to
Did you think you would actually get an intelligent answer here?
Posted by LSUtiger17
New Orleans
Member since Mar 2009
3082 posts
Posted on 3/18/21 at 12:41 pm to
quote:

quote:
mRNA vaccines contain material from the virus that causes COVID-19 that gives our cells instructions for how to make a harmless protein that is unique to the virus. After our cells make copies of the protein, they destroy the genetic material from the vaccine. Our bodies recognize that the protein should not be there and build T-lymphocytes and B-lymphocytes that will remember how to fight the virus that causes COVID-19 if we are infected in the future


This is my issue. I'm not an anti-vaccer by any means, but I'm young and not at risk of complications from the virus. Why does this harmless protein not induce serious illness like the virus can. How are we sure that it doesn't lead to underlying or latent conditions which have not been yet observed because their latency is longer than 7 months or however long this vaccine has existed? Is there any concern that the existence of this protein could lead to future effects that are as of now unknown?
This post was edited on 3/18/21 at 12:42 pm
Posted by nerd guy
Grapevine
Member since Dec 2008
12715 posts
Posted on 3/18/21 at 12:44 pm to
The mRNA is probably cloaked somehow. Bet the answer is in here.

LINK
Posted by Jake88
Member since Apr 2005
68279 posts
Posted on 3/18/21 at 12:44 pm to
The immune system doesn't see the mRNA. It is carried in a lipophillic "envelope" that is able to pass through the cells' lipid based membrane.

Think of it like this...all of the neighborhoods going up in SE Louisiana have either a French country style or Acadian style made of wood, bricks and stucco. Suddenly someone uses those same building materials to build a Hanok style house in the neighborhood. Yoyre going to recognize it as different, correct?
This post was edited on 3/18/21 at 12:51 pm
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