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If we cloned ancient human DNA would they be deficient today?

Posted on 8/2/20 at 9:29 pm
Posted by Kujo
225-911-5736
Member since Dec 2015
6015 posts
Posted on 8/2/20 at 9:29 pm
If we got the go ahead for a worldwide project to clone hundreds of ancient humans in say 5 groups of 10k years old, 5k years old, 2k, 1k and 500 years old, and raised them as normal children would they have a harder time in school?

How much different is our brain today than 2k years ago? Is 2k years of "evolution" indistinguishable?

I look at things like eyesight and height and see that they can change in little to no time:
example eyesight
quote:

About 30 per cent of Hongkongers born before 1950 are myopic, according to a report by the Centre for Myopia Research at Polytechnic University, but that rate shoots up to 70 per cent for those born between 1950 and 1980.

example height
quote:

In fact, over the last 150 years, the average height of people in industrialized nations has increased approximately 10 centimeters (about four inches). In the first half of the 18th century, the average height of an English male was 165 cm (5 ft 5 in)



I know a quick rebuttal may be "external forces" ie. Computer/reading more.common (eyesight) and medicine & nutrition advances(height) but I not completely convinced that there isn't some adaptation/evolution going on as well.

So the question, if we grabbed your 10k year old ancestors DNA, would you expect them to be as normal as anyone today?
Posted by Tiguar
Montana
Member since Mar 2012
33131 posts
Posted on 8/2/20 at 9:31 pm to
I got a feeling cloning our ancestors from 10k years ago would put a big ol fat anchor around the neck of the “we’re all equal” crowd.
Posted by The Pirate King
Pangu
Member since May 2014
57681 posts
Posted on 8/2/20 at 9:32 pm to
I would assume their immune systems (or lack there of) would get them killed.
Posted by Adam4848
LA
Member since Apr 2006
18960 posts
Posted on 8/2/20 at 9:33 pm to
Posted by Athis
Member since Aug 2016
11599 posts
Posted on 8/2/20 at 9:33 pm to
We got enough of those cave men running around today...
Posted by Oilfieldbiology
Member since Nov 2016
37495 posts
Posted on 8/2/20 at 9:38 pm to
No
Posted by Kentucker
Cincinnati, KY
Member since Apr 2013
19351 posts
Posted on 8/2/20 at 9:41 pm to
quote:

About 30 per cent of Hongkongers born before 1950 are myopic, according to a report by the Centre for Myopia Research at Polytechnic University, but that rate shoots up to 70 per cent for those born between 1950 and 1980.


You answered this one in your OP.

quote:

n fact, over the last 150 years, the average height of people in industrialized nations has increased approximately 10 centimeters (about four inches). In the first half of the 18th century, the average height of an English male was 165 cm (5 ft 5 in)


The biggest change in height is because of better nutrition over the past 150 years. For a long time Americans were among the tallest people on earth because of our superior nutrition that’s provided by our farming. Now, however, most of the world has access to good nutrition and many nations’ populations can achieve the maximum heights that their genes are programmed for. In short, it isn’t evolution, just better food.
Posted by Kujo
225-911-5736
Member since Dec 2015
6015 posts
Posted on 8/2/20 at 10:34 pm to
if we went back 50k to 80k years ago? How about 150k to 400k years ago. How many thousands of years back into human evolution would we have to clone before you would definitely say...."yeah, they would struggle?"
This post was edited on 8/2/20 at 10:35 pm
Posted by mmmmmbeeer
ATL
Member since Nov 2014
7431 posts
Posted on 8/2/20 at 10:56 pm to
I have no feedback to provide, but this is actually a pretty damn interesting thing to think about.
Posted by Mike da Tigah
Bravo Romeo Lima Alpha
Member since Feb 2005
58870 posts
Posted on 8/2/20 at 11:06 pm to
quote:

I would assume their immune systems (or lack there of) would get them killed.


I would think so as well. No immunity to a lot of things we have immunity to over the years would be a hard thing to overcome.


Posted by cssamerican
Member since Mar 2011
7119 posts
Posted on 8/2/20 at 11:26 pm to
Well, 2k years ago people built Rome without computers and modern equipment, so I don’t think they were lacking intelligence. I think the Sphinx is dated to something like 4k years ago. I have a feeling you would have to go back pretty far before you started to see lack of capacity in intelligence.
Posted by GoldenGuy
Member since Oct 2015
10875 posts
Posted on 8/2/20 at 11:30 pm to
quote:

I would think so as well. No immunity to a lot of things we have immunity to over the years would be a hard thing to overcome.



I figure their immune system can probably handle a polio shot too.
Posted by DiamondDog
Louisiana
Member since Nov 2019
10565 posts
Posted on 8/2/20 at 11:46 pm to
I’m sure the great minds that brought about the engineering feats such as the wheel would excel in modern day civil engineering.
Posted by Corso
Atlanta
Member since Feb 2020
10673 posts
Posted on 8/2/20 at 11:56 pm to
The folks that built the pyramids are more than welcome to come back and build some new interstates and highways
Posted by Korkstand
Member since Nov 2003
28707 posts
Posted on 8/3/20 at 12:20 am to
quote:

if we went back 50k to 80k years ago? How about 150k to 400k years ago. How many thousands of years back into human evolution would we have to clone before you would definitely say...."yeah, they would struggle?"
I would guess 100k+ years, but maybe a lot further back than that. I don't think our skulls have changed much for about 200k years, and actually our brains have been getting smaller recently.

Chimps and gorillas can learn sign language and how to use tools, and Koko the gorilla supposedly had an IQ of 75+ and could understand 2,000 words. If they can learn that much with brains 1/3rd the size of ours, I don't think a human from 100k years ago would have any trouble at all learning what we know.
Posted by TheFlyingTiger
Member since Oct 2009
3994 posts
Posted on 8/3/20 at 12:28 am to
genetically, by the code, there'd prolly be very minor differences.

epigenetically it'd be off the scales. their genes expressed because of environmental factors, and those of their parents and grandparents would be drastically different.
This post was edited on 8/3/20 at 12:30 am
Posted by Volvagia
Fort Worth
Member since Mar 2006
51904 posts
Posted on 8/3/20 at 12:51 am to
quote:

would assume their immune systems (or lack there of) would get them killed.


Not really how immune systems work. They’ll need help as an infant but it will be more due to the artificial nature of birth than a genetic deficiency (mother’s immune system confers a life raft of acquired immunity for around the first six months after birth).
Posted by Tunasntigers92
The Boot
Member since Sep 2014
23658 posts
Posted on 8/3/20 at 12:53 am to
It would be Africa
Posted by Porcine Human
Fayetteville, Arkansas
Member since Feb 2016
11220 posts
Posted on 8/3/20 at 12:59 am to
No, they would be mostly the same.
Posted by Korkstand
Member since Nov 2003
28707 posts
Posted on 8/3/20 at 2:02 am to
quote:

Not really how immune systems work.
You don't think that our co-evolution with viruses and bacteria could make an ancient human more susceptible today? Don't we benefit from the fact that our ancestors were the ones who survived thousands of years of outbreaks of disease? Our genes are the ones that survived the filters of past pandemics.
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