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re: German Study: 34% of healthy individuals may have a different type of immunity to COVID

Posted on 5/7/20 at 5:30 pm to
Posted by Oilfieldbiology
Member since Nov 2016
37429 posts
Posted on 5/7/20 at 5:30 pm to
quote:

So basically this means we need to extend the lockdown until the federal government pays for my mistakes.”


Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 5/7/20 at 5:31 pm to
quote:

I have been telling my wife for a month that there are oddities in the statistics about this virus that will end up explained by one of two things: either way more people have had Covid-19 than we thought (like over 50%), or some people can’t get it. Antibody tests show that the first is not likely, therefore large numbers of people can’t get COVID-19. Why? I don’t know. But this study hypothesizes just such. An example of the statistical oddities is that over and over we see 20 % as the top percentage of people in a highly exposed group who catch it. The Diamond Princess, for example.


I couldn’t agree with you more
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 5/15/20 at 10:59 am to
Research team from La Jolla confirms this finding and find 50% of random samples from 2015-2018 had these T cells!

This may be playing a significant role in the strange patterns in spread and severity we are seeing.

quote:

The La Jolla team detected this crossreactivity in about half of stored blood samples collected between 2015 and 2018, well before the current pandemic began. The researchers think these cells were likely triggered by past infection with one of the four human coronaviruses that cause colds; proteins in these viruses resemble those of SARS-CoV-2.


LINK

Serious question: when do we start infecting people with common cold coronavirus? If we can prove those recovered patients are the ones have almost undetectable symptoms
This post was edited on 5/15/20 at 11:01 am
Posted by BRIllini07
Baton Rouge, LA
Member since Feb 2015
3012 posts
Posted on 5/15/20 at 11:16 am to
quote:

Serious question: when do we start infecting people with common cold coronavirus? If we can prove those recovered patients are the ones have almost undetectable symptoms


Good question. I would imagine this would be safer than a human challenge study with a vaccine?

Trigger Warning - CNN
Posted by BluegrassBelle
RIP Hefty Lefty - 1981-2019
Member since Nov 2010
98914 posts
Posted on 5/15/20 at 11:21 am to
quote:

when do we start infecting people with common cold coronavirus?


I'll save you a lot of money. Just go volunteer at your local public school. We'll get you infected efficiently and at low cost.
Posted by DeltaTigerDelta
Member since Jan 2017
11258 posts
Posted on 5/15/20 at 11:34 am to
Tiger Blood. It works for Charlie Sheen.
Posted by Penrod
Member since Jan 2011
39098 posts
Posted on 5/15/20 at 12:48 pm to
Good find!
Posted by Sasquatch Smash
Member since Nov 2007
23979 posts
Posted on 5/15/20 at 1:00 pm to
quote:

quote:

when do we start infecting people with common cold coronavirus?



I'll save you a lot of money. Just go volunteer at your local public school. We'll get you infected efficiently and at low cost.


Since seeing the earlier study in this thread, I've thought that a good test group to check for this, as far as adults are concerned, would be school teachers.
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 5/15/20 at 1:53 pm to
If this hypothesis is true you have to wonder what the lockdowns did to the spread of common cold coronaviruses. I’m sure it wiped out those and they could have been circulating giving us a protective effect. If there is a second wave does this play in to it?

Luckily it appears T cell immunity lasts much longer, even years, after infection.
Posted by Sasquatch Smash
Member since Nov 2007
23979 posts
Posted on 5/15/20 at 2:14 pm to
quote:

If this hypothesis is true you have to wonder what the lockdowns did to the spread of common cold coronaviruses. I’m sure it wiped out those and they could have been circulating giving us a protective effect. If there is a second wave does this play in to it?


Saying that we might have fricked ourselves even further by shutting off this possible route to helpful immunity by closing schools?

Hmmm....

quote:

Luckily it appears T cell immunity lasts much longer, even years, after infection.


Yeah...let's hope this is a real thing. Would go a long way in this whole fiasco.
Posted by BRIllini07
Baton Rouge, LA
Member since Feb 2015
3012 posts
Posted on 5/15/20 at 2:23 pm to
I wonder if this explains some of the military vs. dependent data:

Albeit too low of a numerator in both cases to draw any significance whatsoever (other than to say the mortality rate is low in these groups).

Active duty: 5472 cases, 2 deaths (0.037%)
Dependents: 987 cases, 4 deaths (0.41%) or 10x higher.

Dependents are the spouses or children of active duty, so age grouping is comparable.

Some comorbidities (extreme obesity, T1 diabetes) would be excluded from the Active Duty group but not the dependent group. It's certainly feasible that there a 4 poorly controlled diabetics in the military dependent group.

But, I remember in my boot camp group just about everyone picked up a cold/flu a few weeks into boot camp. This was explained as being exposed to all the variations of colds, flus, etc. that existed throughout the country that now get exposed to new hosts when 80+ people from everywhere get together in close contact for a few months.
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 5/15/20 at 2:39 pm to
It’s possible but I think your other hypothesis of weeding out comorbidities is probably more likely.

However, we have to consider that most active military are male so their dependents are female and children, two groups which should be less effected than men. So it is very interesting.

Do they get a MMR booster in basic training? I know nothing about the military
Posted by NoHoTiger
So many to kill, so little time
Member since Nov 2006
45721 posts
Posted on 5/15/20 at 2:44 pm to
quote:

“So basically this means we need to extend the lockdown for 45 more weeks”

- John Bel Edwards

Eric Garcetti. L.A.: "Can I get in on this?"
Posted by Sasquatch Smash
Member since Nov 2007
23979 posts
Posted on 5/15/20 at 2:50 pm to
quote:

MMR booster


How's the factor looking?
Posted by rocket31
Member since Jan 2008
41819 posts
Posted on 5/15/20 at 3:02 pm to
good thread, its becoming patently obvious that this whole thing was overblown especially for healthy people.

my biggest concerns/questions are what the govt does in the fall to "control" us

do we have football, basketball, baseball, concerts, festivals?

Posted by BRIllini07
Baton Rouge, LA
Member since Feb 2015
3012 posts
Posted on 5/15/20 at 3:51 pm to
I want to say I got 2 vaccination shots in each shoulder + the penicillin shot in the arse.

I’ll see if I can find what they were. I would imagine tetanus, MMR, flu, and something?
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 5/15/20 at 4:20 pm to
quote:

How's the factor looking?


I’m not sure what you mean.

There is a theory that the MMR vaccine can give some immunity against the spike protein on SARS-CoV-2. If the active military got those boosters and their age matched dependents didn’t and we are seeing such a difference in mortality rate despite them being in a higher risk category then that is significant information.
Posted by Sasquatch Smash
Member since Nov 2007
23979 posts
Posted on 5/15/20 at 4:24 pm to
quote:

’m not sure what you mean.

There is a theory that the MMR vaccine can give some immunity against the spike protein on SARS-CoV-2. If the active military got those boosters and their age matched dependents didn’t and we are seeing such a difference in mortality rate despite them being in a higher risk category then that is significant information.



Right. I was asking if there have been any more details regarding this hypothesis.
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 5/15/20 at 4:43 pm to
Not that I’ve heard. I know Tulane medical center just started research on this issue last week.
Posted by AbuTheMonkey
Chicago, IL
Member since May 2014
7994 posts
Posted on 5/15/20 at 5:01 pm to
quote:

It’s possible but I think your other hypothesis of weeding out comorbidities is probably more likely.

However, we have to consider that most active military are male so their dependents are female and children, two groups which should be less effected than men. So it is very interesting.

Do they get a MMR booster in basic training? I know nothing about the military



It's been more than a decade, but you have to be updated on your vaccines before you ship off to basic and then you get a whole slew of crap before you deploy overseas (stuff that you'd never get in the regular world like anthrax).
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