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Bwmdx
Member since Dec 2018
606 posts
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re: German Study: 34% of healthy individuals may have a different type of immunity to COVID
This goes back to the “sterilization” of our environment. In the long run this is a detriment to our immune systems. It’s seems logical that their would be non-fatal infectious disease that carry cross immunity to others. If we strip our bodies of that initial benign infectious challenge then we may be leaving our selves more susceptible to future more virulent and fatal infections.


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Sasquatch Smash
LSU Fan
Member since Nov 2007
10066 posts

re: German Study: 34% of healthy individuals may have a different type of immunity to COVID
Another preprint concerning pre-existing immunity.


WaWaWeeWa
Member since Oct 2015
7834 posts
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re: German Study: 34% of healthy individuals may have a different type of immunity to COVID
Good find. The evidence is mounting.


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WaWaWeeWa
Member since Oct 2015
7834 posts
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re: German Study: 34% of healthy individuals may have a different type of immunity to COVID
LINK

Former director of WHO, so he’s off of China’s payroll and can speak freely. This is what I’ve been speculating. The curve is pretty much the same everywhere. We never saw exponential growth anywhere. Something else is at play here.

quote:

Professor Karol Sikora, an oncologist and chief medical officer at Rutherford Health, said the public probably has more immunity to Covid-19 than realised. He thought the virus could end up “petering out by itself”. Writing on social media he explained: “There is a real chance that the virus will burn out naturally before any vaccine is developed. “We are seeing a roughly similar pattern everywhere – I suspect we have more immunity than estimated.


Sasquatch Smash
LSU Fan
Member since Nov 2007
10066 posts

re: German Study: 34% of healthy individuals may have a different type of immunity to COVID
quote:

Professor Karol Sikora


He's on the latest (today's) LockdownTV.


WaWaWeeWa
Member since Oct 2015
7834 posts
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re: German Study: 34% of healthy individuals may have a different type of immunity to COVID
He nails it. All the curves indicate something else at play. There is likely an immunity that could be eliminating some infections before antibodies can even be made. So antibody tests don’t fully capture the amount who have been infected or the amount who are still vulnerable.

Just watch a place like Brazil. No way they can social distance, but they will level off here shortly. Or a place like Iran with 82 million people, you think they can social distance? Not a chance.
This post was edited on 5/18 at 7:53 pm


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WaWaWeeWa
Member since Oct 2015
7834 posts
 Online 

re: German Study: 34% of healthy individuals may have a different type of immunity to COVID
LINK

New study shows that only 25% of people with an asymptomatic infection developed antibodies.

These people probably have some previous immunity like mentioned in the OP.

This means the antibody tests likely vastly underestimate the amount of people who have been infected or are resistant to any meaningful infection.


WaWaWeeWa
Member since Oct 2015
7834 posts
 Online 

re: German Study: 34% of healthy individuals may have a different type of immunity to COVID
Latest paper out of Cell

quote:

Importantly, we detected SARS-CoV-2-reactive CD4+ T cells in ~40-60% of unexposed individuals, suggesting cross-reactive T cell recognition between circulating ‘common cold’ coronaviruses and SARS-CoV-2.


The pandemic is ending because we are nearing herd immunity in most places.

When we look back on this and study it I’m confident this will be the key to the entire thing. There was previous immunity. We didn’t do very much with lockdown.


WaWaWeeWa
Member since Oct 2015
7834 posts
 Online 

re: German Study: 34% of healthy individuals may have a different type of immunity to COVID
They also comment on how this previous T cell immunity was probably responsible for the mildness of the H1N1 pandemic

quote:

Regarding the value of crossreactive T cells, influenza (flu) immunology in relationship to pandemics may be instructive. In the context of the 2009 H1N1 influenza pandemic, preexisting T cell immunity existed in the adult population, which focused on the more conserved internal influenza viral proteins (Greenbaum et al., 2009). The presence of crossreactive T cells was found to correlate with 7 less severe disease (Sridhar et al., 2013; Wilkinson et al., 2012). The frequent availability of cross- reactive memory T cell responses might have been one factor contributing to the lesser severity of the H1N1 flu pandemic (Hancock et al., 2009). Cross-reactive immunity to influenza strains has been modeled to be a critical influencer of susceptibility to newly emerging, potentially pandemic, influenza strains (Gostic et al., 2016). Given the severity of the ongoing COVID-19 pandemic, it has been modeled that any degree of crossprotective coronavirus immunity in the population could have a very substantial impact on the overall course of the pandemic, and the dynamics of the epidemiology for years to come (Kissler et al., 2020).
This post was edited on 5/23 at 10:33 am


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Ross
Auburn Fan
Huntsville, AL
Member since Oct 2007
40940 posts

re: German Study: 34% of healthy individuals may have a different type of immunity to COVID
quote:

We didn’t do very much with lockdown.


When we all congregate at the same grocery stores, it was inevitable that the lockdowns would only marginally work to slow the spread anyway. It’s a whole lot of financial ruin brought on with only marginal results to show for it, in all likelihood.


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