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Message
German Study: 34% of healthy individuals may have a different type of immunity to COVID
Posted on 5/6/20 at 6:45 pm
Posted on 5/6/20 at 6:45 pm
Pre-print study
This is going to be lengthy but hang in there and I’ll explain it all.
Our body has multiple defenses to virus and bacteria. Think of it like the Army, Navy, and Air Force. The two main defenses in humans are B cells and T cells. All of the antibody studies you have been hearing about are B cells.
So far no one has been exploring the possibility that T cells could be playing a role in Coronavirus. This study demonstrates that patients that have NEVER BEEN INFECTED with coronavirus have certain T cells that react to the virus.
This means that POTENTIALLY there could be a large percentage of people that are naturally immune to the virus due to previous infections with other coronaviruses. (FYI kids pass around a lot of coronaviruses.)
This is a hypothesis but it is very interesting and it could explain why we see pockets of infection in certain areas as well as very low transmission within households of only 15%. It’s very strange that a contagious virus only has a 15% chance to infect others in the house. Some already having natural immunity would explain this.
Update:
Latest paper out of Cell
The pandemic is ending because we are nearing herd immunity in most places IMO
This is going to be lengthy but hang in there and I’ll explain it all.
Our body has multiple defenses to virus and bacteria. Think of it like the Army, Navy, and Air Force. The two main defenses in humans are B cells and T cells. All of the antibody studies you have been hearing about are B cells.
So far no one has been exploring the possibility that T cells could be playing a role in Coronavirus. This study demonstrates that patients that have NEVER BEEN INFECTED with coronavirus have certain T cells that react to the virus.
This means that POTENTIALLY there could be a large percentage of people that are naturally immune to the virus due to previous infections with other coronaviruses. (FYI kids pass around a lot of coronaviruses.)
This is a hypothesis but it is very interesting and it could explain why we see pockets of infection in certain areas as well as very low transmission within households of only 15%. It’s very strange that a contagious virus only has a 15% chance to infect others in the house. Some already having natural immunity would explain this.
Update:
Latest paper out of Cell
quote:
Importantly, we detected SARS-CoV-2-reactive CD4+ T cells in ~40-60% of unexposed individuals, suggesting cross-reactive T cell recognition between circulating ‘common cold’ coronaviruses and SARS-CoV-2.
The pandemic is ending because we are nearing herd immunity in most places IMO
This post was edited on 5/23/20 at 9:56 am
26
Posted on 5/6/20 at 6:46 pm to WaWaWeeWa
Layman's terms is not being fat.
Posted on 5/6/20 at 6:47 pm to WaWaWeeWa
O P E N U P
P
E
N
U
P
P
E
N
U
P
Posted on 5/6/20 at 6:47 pm to WaWaWeeWa
can we go to Chili’s yet?
Posted on 5/6/20 at 6:49 pm to WaWaWeeWa
quote:
This is a hypothesis but it is very interesting and it could explain why we see pockets of infection in certain areas as well as very low transmission within households of only 15%. It’s very strange that a contagious virus only has a 15% chance to infect others in the house.
This is consistent with the infection rates from contained environments like the cruise ships and naval vessels where this should’ve been spreading like wildfire.
quote:
Some already having natural immunity would explain this.
But we’ve been told over and over again that no one has natural immunity to this novel virus.
Posted on 5/6/20 at 6:50 pm to ell_13
Now I’m going to make a huge assumption....
If we assume 34% have some type of previous natural immunity and 20% of an area like New Orleans has already been infected (estimated by some Ochsner research I’ve heard of)...
Then we are at 54% and the virus does not have very many available hosts left and we should see a naturally slowing of infections regardless of what we do with lockdowns, etc.
If we assume 34% have some type of previous natural immunity and 20% of an area like New Orleans has already been infected (estimated by some Ochsner research I’ve heard of)...
Then we are at 54% and the virus does not have very many available hosts left and we should see a naturally slowing of infections regardless of what we do with lockdowns, etc.
This post was edited on 5/6/20 at 6:51 pm
Posted on 5/6/20 at 6:51 pm to LegendInMyMind
quote:
Literally Germans.
Posted on 5/6/20 at 6:52 pm to WaWaWeeWa
Please don't try to teach anyone about how immunity works. I don't have enough time or fricks to give to correct your explanation.
Posted on 5/6/20 at 6:52 pm to WaWaWeeWa
“So basically this means we need to extend the lockdown for 45 more weeks”
- John Bel Edwards
- John Bel Edwards
Posted on 5/6/20 at 6:53 pm to WaWaWeeWa
very interesting. This, coupled with the recent french communication about a hospitalized patient from december who they retroactively tested samples from and found them to be + for covid suggests that in addition to this virus being around much longer than previously thought, many are immune to it from past coronavirus exposures.
Posted on 5/6/20 at 6:56 pm to nvcowboyfan
It’s important to remember that none of this has been proven but it could explain a lot of the unusual patterns we are seeing with this virus.
Posted on 5/6/20 at 6:57 pm to WaWaWeeWa
quote:
If we assume 34% have some type of previous natural immunity and 20% of an area like New Orleans has already been infected (estimated by some Ochsner research I’ve heard of)...
There is zero reason to believe the two pots are separate. If this pans out, it is more likely to explain the high degree of asymptomatic/mild cases we have already seen.
Not this silent background of 100% immunity. T cells can only react after the cells are showing viral proteins so you must have an active infection.
This post was edited on 5/6/20 at 6:58 pm
Posted on 5/6/20 at 7:05 pm to Volvagia
quote:
If this pans out, it is more likely to explain the high degree of asymptomatic/mild cases we have already seen.
I agree. But does everyone with T cell immunity develop detectable B cell immunity?
quote:
T cells can only react after the cells are showing viral proteins so you must have an active infection.
Unless they cross react with other coronaviruses like hypothesized in the paper.
Posted on 5/6/20 at 7:06 pm to Volvagia
What about the few studies out there looking at the MMR vaccine and it’s possible effectiveness against COVID? Several researchers out there have asserted that this could explain why up to about 50 years old or so, the infection rate is not as bad and the outcomes of those infected not as severe. It apparently is 20% identical to measles and 29% identical to rubella. Thoughts?
Posted on 5/6/20 at 7:07 pm to WaWaWeeWa
I agree. I'm still thinking that the very low #'s in the west coast (california with less than 2000 deaths) leads me to believe that this was spread slowly in the fall in the west coast.
Posted on 5/6/20 at 7:08 pm to S1C EM
quote:
Thoughts?
It’s possible. Tulane is researching this now. However I think it’s unlikely.
I’ll give you what I think is a better hypothesis related to this thread....
T cell function decreases with age
Posted on 5/6/20 at 7:35 pm to Open Your Eyes
quote:
Some already having natural immunity would explain this.
Like, say, Aryans?
Posted on 5/6/20 at 7:44 pm to WaWaWeeWa
That's very interesting.
It does make me wonder though about all the prison reports lately where seemingly almost all the inmates/employees tested positive with no symptoms.
Am I assuming incorrectly that "people that are naturally immune" would not test positive?
Is it possible that there are just a lot of different variations/mutations of this virus?
Posted on 5/6/20 at 7:53 pm to WaWaWeeWa
quote:
Unless they cross react with other coronaviruses like hypothesized in the paper.
Even then.
What you describe would only mean that the T cells could identify infected cells and send a kill signal.
It doesn't directly attack loose virus like antibodies/B cells do.
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