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re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***

Posted on 3/9/20 at 5:11 pm to
Posted by 1BamaRTR
In Your Head Blvd
Member since Apr 2015
24837 posts
Posted on 3/9/20 at 5:11 pm to
At this point, this thread is filled with just as many people saying it’s not a big deal at all than it is with people saying it’s an issue
Posted by ell_13
Member since Apr 2013
88012 posts
Posted on 3/9/20 at 5:11 pm to
quote:

No you don’t. I can promise you that the physicians that get diagnosed early will want meds that have shown some results in China.
There you go making stuff up. Want me to quote the pediatric post from a few pages back? Or any of the articles sent to me by my doc friends?
Posted by Scruffy
Kansas City
Member since Jul 2011
77270 posts
Posted on 3/9/20 at 5:12 pm to
quote:

No you don’t. I can promise you that the physicians that get diagnosed early will want meds that have shown some results in China.
Their process and management is even more confusing than their numbers.

They were literally throwing everything at patients.

We know that the vast majority of anti-virals are very selective in their activity and wouldn’t work.

That is the biggest issue. We would have zero idea what to take from those reports.
This post was edited on 3/9/20 at 5:14 pm
Posted by tigerskin
Member since Nov 2004
46735 posts
Posted on 3/9/20 at 5:13 pm to
I am on a huge private worldwide physician board. I promise you they know more than your local pediatrician.
This post was edited on 3/9/20 at 5:14 pm
Posted by Tiguar
Montana
Member since Mar 2012
33131 posts
Posted on 3/9/20 at 5:14 pm to
Chloroquine is actually showing some efficacy oddly enough.

We bought a bunch of hydroxychloroquine since it should have some efficacy since they both have a similar pKa and work by alkalizing lysosomes
Posted by ell_13
Member since Apr 2013
88012 posts
Posted on 3/9/20 at 5:15 pm to
Well I’m on a huger and privater board than you and they laugh at your board all the time.
Posted by tigerskin
Member since Nov 2004
46735 posts
Posted on 3/9/20 at 5:17 pm to
No you aren’t
Posted by ell_13
Member since Apr 2013
88012 posts
Posted on 3/9/20 at 5:19 pm to
What!!! How dare you not believe an anonymous person on the internet!!!
Posted by TigerChief10
Member since Dec 2012
10858 posts
Posted on 3/9/20 at 5:19 pm to
quote:

At this point, this thread is filled with just as many people saying it’s not a big deal at all than it is with people saying it’s an issue

I'm so sorry people with common sense infiltrated yalls armageddon circle jerk
Posted by 1BamaRTR
In Your Head Blvd
Member since Apr 2015
24837 posts
Posted on 3/9/20 at 5:21 pm to
Except there wasn’t an Armageddon circle jerk. There were some doomsayers trolls and misinformed (like the HIV hoax) ones but not really much of the I’m going to stock up on hand sanitizer and toilet paper types you’re pissed about.
Posted by tigerskin
Member since Nov 2004
46735 posts
Posted on 3/9/20 at 5:22 pm to
I will continue to post relevant info and you can continue to troll:

From an ID conference in California

3/8/2020

“Notes from the front lines:
I attended the Infectious Disease Association of California (IDAC) Northern California Winter Symposium on Saturday 3/7. In attendance were physicians from Santa Clara, San Francisco and Orange Counties who had all seen and cared for COVID-19 patients, both returning travelers and community-acquired cases. Also present was the Chief of ID for Providence hospitals, who has 2 affected Seattle hospitals under his jurisdiction. Erin Epson, CDPH director of Hospital Acquired Infections, was also there to give updates on how CDPH and CDC are handling exposed health care workers, among other things. Below are some of the key take-aways from their experiences.

1. The most common presentation was one week prodrome of myaglias, malaise, cough, low grade fevers gradually leading to more severe trouble breathing in the second week of illness. It is an average of 8 days to development of dyspnea and average 9 days to onset of pneumonia/pneumonitis. It is not like Influenza, which has a classically sudden onset. Fever was not very prominent in several cases. The most consistently present lab finding was lymphopenia (with either leukocytosis or leukopenia). The most consistent radiographic finding was bilateral interstitial/ground glass infiltrates. Aside from that, the other markers (CRP, PCT) were not as consistent.

2. Co-infection rate with other respiratory viruses like Influenza or RSV is <=2%, interpret that to mean if you have a positive test for another respiratory virus, then you do not test for COVID-19. This is based on large dataset from China.

3. So far, there have been very few concurrent or subsequent bacterial infections, unlike Influenza where secondary bacterial infections are common and a large source of additional morbidity and mortality.

4. Patients with underlying cardiopulmonary disease seem to progress with variable rates to ARDS and acute respiratory failure requiring BiPAP then intubation. There may be a component of cardiomyopathy from direct viral infection as well. Intubation is considered “source control” equal to patient wearing a mask, greatly diminishing transmission risk. BiPAP is the opposite, and is an aerosol generating procedure and would require all going into the room to wear PAPRs.

5. To date, patients with severe disease are most all (excepting those whose families didn’t sign consent) getting Remdesivir from Gilead through compassionate use. However, the expectation is that avenue for getting the drug will likely close shortly. It will be expected that patients would have to enroll in either Gilead’s RCT (5 vs 10 days of Remdesivir) or the NIH’s “Adaptive” RCT (Remdesivir vs. Placebo). Others have tried Kaletra, but didn’t seem to be much benefit.

6. If our local MCHD lab ran out of test kits we could use Quest labs to test. Their test is 24-48 hour turn-around-time. Both Quest and ordering physician would be required to notify Public Health immediately with any positive results. Ordering physician would be responsible for coordinating with the Health Department regarding isolation. Presumably, this would only affect inpatients though since we (CHOMP) have decided not to collect specimens ordered by outpatient physicians.

7. At facilities that had significant numbers of exposed healthcare workers they did allow those with low and moderate risk exposures to return to work well before 14 days. Only HCW with highest risk exposures were excluded for almost the full 14 days (I think 9 days). After return to work, all wore surgical masks while at work until the 14 days period expired. All had temperature check and interview with employee health prior to start of work, also only until the end of the 14 days. Obviously, only asymptomatic individuals were allowed back.

8. Symptom onset is between 2-9 days post-exposure with median of 5 days. This is from a very large Chinese cohort.

9. Patients can shed RNA from 1-4 weeks after symptom resolution, but it is unknown if the presence of RNA equals presence of infectious virus. For now, COVID-19 patients are “cleared” of isolation once they have 2 consecutive negative RNA tests collected >24 hours apart.

10. All suggested ramping up alternatives to face-to-face visits, tetemedicine, “car visits”, telephone consultation hotlines.

11. Sutter and other larger hospital systems are using a variety of alternative respiratory triage at the Emergency Departments.

12. Health Departments (CDPH and OCHD) state the Airborne Infection Isolation Room (AIIR) is the least important of all the suggested measures to reduce exposure. Contact and droplet isolation in a regular room is likely to be just as effective. One heavily affected hospital in San Jose area is placing all “undifferentiated pneumonia” patients not meeting criteria for COVID testing in contact+droplet isolation for 2-3 days while seeing how they respond to empiric treatment and awaiting additional results.

Feel free to share. All PUIs in Monterey Country so far have been negative.”

Martha L. Blum, MD, PhD
This post was edited on 3/9 at 3:52 pm
Posted by ell_13
Member since Apr 2013
88012 posts
Posted on 3/9/20 at 5:23 pm to
No. Just the ones telling people that 8 million people in the US will end up in the ICU and hundreds of thousands will die.
Posted by HerbEaverstinks
Member since Jan 2011
4516 posts
Posted on 3/9/20 at 5:23 pm to
I put the line on the president and task force finally stepping up to the podium at the bottom of the hour, so they can make the nightly news go live and cut them out.

Line - bottom of the hour

Over or under?
Posted by tigerskin
Member since Nov 2004
46735 posts
Posted on 3/9/20 at 5:26 pm to
Louisiana’s current testing criteria:

Criteria to Guide Evaluation of Persons Under Investigation for COVID-19
Clinical Features
Fever1 or signs/symptoms of lower respiratory illness (e.g. cough or shortness of breath)
AND
Epidemiologic Risk
Close contact with a laboratory-confirmed COVID-19 patient within 14 days of symptom onset

Clinical Features
Fever1 and signs/symptoms of a lower respiratory illness (e.g., cough or shortness of breath)
AND
Epidemiologic Risk
A history of travel from affected geographic areas2 within 14 days of symptom onset

Clinical Features
Fever1 with severe acute lower respiratory illness (e.g., pneumonia, ARDS [acute respiratory distress syndrome]) requiring hospitalization and without alternative explanatory diagnosis (e.g., influenza)
AND
Epidemiologic Risk
No identified source of exposure

1Measured as = 100.4°F.

2Affected geographic areas are defined as countries assigned a level 2 or 3 travel health notice by CDC or other areas determined to have sustained community transmission.
Posted by 1BamaRTR
In Your Head Blvd
Member since Apr 2015
24837 posts
Posted on 3/9/20 at 5:26 pm to
That’s not really what he meant. Several pages back he even said this would be a shitty bioweapon because of the low death rate in response to the poster saying this could be a bioweapon.
Posted by ell_13
Member since Apr 2013
88012 posts
Posted on 3/9/20 at 5:27 pm to
Glad Tiguar was wrong.
This post was edited on 3/9/20 at 5:27 pm
Posted by ell_13
Member since Apr 2013
88012 posts
Posted on 3/9/20 at 5:28 pm to
Well yeah. He changed his tune once it was obvious this is much closer to the flu than the China data suggested when he first made that post.
Posted by tigerfoot
Alexandria
Member since Sep 2006
61448 posts
Posted on 3/9/20 at 5:30 pm to
quote:

Well I’m on a huger and privater board than you and they laugh at your board all the time.


what are you looking to gain here? Ive never known you to just be an a-hole for the sake of being an a-hole.
Posted by jennBN
Member since Jun 2010
3250 posts
Posted on 3/9/20 at 5:34 pm to
Thank you for sharing info. I am in California and work in healthcare. What we are seeing is in line with that.

That being said, this thread has been helpful and given good data for quite awhile. I hate that it has been hijacked by assholes that are hellbent on carrying a torch for a political party. I hope that many of you continue to post. Thanks again.
Posted by ell_13
Member since Apr 2013
88012 posts
Posted on 3/9/20 at 5:35 pm to
I’m trying to be lighthearted in my teasing. This obviously isn’t as serious as the reactions to it continue to be and certainly not from a month ago. I’m sure most of the guys here mean well and are rational. Hell, Project and I get along really well but his reaction to the St Louis dad was nonsensical. This is just causing people to act like idiots. I think my worst insult was just calling wewaweewaa a nut. I swear I’m not trying to tear people down besides using what they’ve posted. And I’m not trying to derail anything although I may have continued some things just because this thread helped pass my day. I actually have a math degree so the decimal thing really did make me feel like a moron.
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