- My Forums
- Tiger Rant
- LSU Recruiting
- SEC Rant
- Saints Talk
- Pelicans Talk
- More Sports Board
- Fantasy Sports
- Golf Board
- Soccer Board
- O-T Lounge
- Tech Board
- Home/Garden Board
- Outdoor Board
- Health/Fitness Board
- Movie/TV Board
- Book Board
- Music Board
- Political Talk
- Money Talk
- Fark Board
- Gaming Board
- Travel Board
- Food/Drink Board
- Ticket Exchange
- TD Help Board
Customize My Forums- View All Forums
- Show Left Links
- Topic Sort Options
- Trending Topics
- Recent Topics
- Active Topics
Started By
Message
re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
Posted on 4/29/20 at 8:28 am to GOP_Tiger
Posted on 4/29/20 at 8:28 am to GOP_Tiger
quote:Yehhhhhhhh
It was all stupid, that's what it was. The goal, from the very beginning, should have been to eradicate the virus. That's what Korea, Hong Kong, Taiwan, and now New Zealand have done. Now, everyone in those countries can basically lead normal lives without any fear of COVID-19.
You are incompetent
0
Posted on 4/29/20 at 9:24 am to GOP_Tiger
quote:
It was all stupid, that's what it was. The goal, from the very beginning, should have been to eradicate the virus. That's what Korea, Hong Kong, Taiwan, and now New Zealand have done. Now, everyone in those countries can basically lead normal lives without any fear of COVID-19.
Posted on 4/29/20 at 3:47 pm to Saintsisit
quote:
Do you realize how many international flights arrive here daily? How would that be possible logistically. What about people crossing the border daily?
Do you have any idea how quickly that would drop if people had to stay in quarantine? Or, if it's just too hard, you just stop the flights. That's what Argentina just did -- just shut down all flights until September.
Closing borders is what most European countries have done. Y'all are acting as though it's a crazy thought. You know what's nuts? Destroying your economy and losing tens of thousands of lives because you don't want to do what's necessary.
But if you keep the virus from
Posted on 4/29/20 at 4:05 pm to GOP_Tiger
quote:
quote:
Do you realize how many international flights arrive here daily? How would that be possible logistically. What about people crossing the border daily?
Do you have any idea how quickly that would drop if people had to stay in quarantine? Or, if it's just too hard, you just stop the flights. That's what Argentina just did -- just shut down all flights until September.
Closing borders is what most European countries have done. Y'all are acting as though it's a crazy thought. You know what's nuts? Destroying your economy and losing tens of thousands of lives because you don't want to do what's necessary.
But if you keep the virus from
Given the volume of international travel into and out of the country and the un-mitigated R0 of the virus, there were likely thousands and thousands of cases in this country already by the time the very first travel ban was announced on January 31. There were almost certainly tens of thousands if not hundreds of thousands of cases by the time European travel bans went into effect. That cat was out of the bag and unless someone had superhuman prescience (and this is given that the U.S. could have even logistically pulled it off, which it couldn't and really still can't), there was a big enough cluster in the country by late January that pandemic spread was going to happen whether we wanted it to or not.
Given that, the likelihood of getting the R0 down low enough for a sustained enough period of time here to completely suppress it is impossible given our culture, society, and politics. You have to do full-on, Wuhan-style, welding doors shut lock down for several months with this virus. It'd have to be both culturally acceptable and politically possible - it isn't - and instituted nationally all at once and for quite a while.
The only way that a major spread wasn't going to happen in the U.S. and western Europe is if the Chinese government had completely shut down things in late December or early January. This virus is going to be with us for a while, and we better get used to it and find a sustainable way of dealing with it for a while.
This post was edited on 4/29/20 at 4:37 pm
Posted on 4/29/20 at 4:09 pm to GOP_Tiger
quote:
Y'all are acting as though it's a crazy thought. You know what's nuts? Destroying your economy and losing tens of thousands of lives because you don't want to do what's necessary.
This is some wonderful revisionist history here.
Is this what everyone who supported the shutdown will start doing?
Switching their rosey-eyed view of the shutdown that they held only one week prior?
The shutdown was the best idea possible.
No regrets at all.
This post was edited on 4/29/20 at 4:14 pm
Posted on 4/29/20 at 6:07 pm to Scruffy
Not sure I understand, Scruffy.
Of course the shutdowns were necessary once the virus had been allowed to spread everywhere. With the exception of Belarus and a couple of other dictatorships, every country in the world has shut stuff down to stop or slow the spread of the virus.
I hate the shutdown. It nearly destroyed my business, and only my PPP money from the SBA is going to keep it going. There's nothing "rosey-eyed" about it at all. I just hate the virus more.
Personally, I look at people like you and think that you don't hate the virus enough, that you put too little value on human life.
But my point was that government competence could have prevented all of this. Could we have stopped all spread of COVID-19 in the US? Of course not. But a big part of our problem was that places like NYC and New Orleans got seeded with big doses of COVID-19. President Trump brags constantly about the restrictions that he put in place on travelers from China -- and that was indeed a great thing and delayed spread here for about two weeks -- but he wouldn't put in place similar restrictions on flights from Italy and the rest of Europe when it was just as necessary.
Of course the shutdowns were necessary once the virus had been allowed to spread everywhere. With the exception of Belarus and a couple of other dictatorships, every country in the world has shut stuff down to stop or slow the spread of the virus.
I hate the shutdown. It nearly destroyed my business, and only my PPP money from the SBA is going to keep it going. There's nothing "rosey-eyed" about it at all. I just hate the virus more.
Personally, I look at people like you and think that you don't hate the virus enough, that you put too little value on human life.
But my point was that government competence could have prevented all of this. Could we have stopped all spread of COVID-19 in the US? Of course not. But a big part of our problem was that places like NYC and New Orleans got seeded with big doses of COVID-19. President Trump brags constantly about the restrictions that he put in place on travelers from China -- and that was indeed a great thing and delayed spread here for about two weeks -- but he wouldn't put in place similar restrictions on flights from Italy and the rest of Europe when it was just as necessary.
Posted on 4/29/20 at 6:17 pm to GOP_Tiger
In real news, though, we finally have a drug that has proven to be an effective treatment against COVID-19 in a proper double-blind clinical trial. The study found that patients treated with remdesivir got well in an average of 11 days instead of 15, a 31% difference.
Only 8% of the patients treated with the drug died, compared to the 11% who didn't get the drug and died, but scientists have to pretend that this difference in death rate isn't statistically significant, because you'd get these results 6% of the time by random chance, and scientists have this completely arbitrary number of 5% that they use to decide whether something is statistically significant or not.
So, you'll see lots of discussion about it helping people get well faster, but they won't talk about it saving people's lives, because it technically isn't proven to do that by the above rule.
The FDA is expected to officially approve remdesivir as a treatment any minute now.
Only 8% of the patients treated with the drug died, compared to the 11% who didn't get the drug and died, but scientists have to pretend that this difference in death rate isn't statistically significant, because you'd get these results 6% of the time by random chance, and scientists have this completely arbitrary number of 5% that they use to decide whether something is statistically significant or not.
So, you'll see lots of discussion about it helping people get well faster, but they won't talk about it saving people's lives, because it technically isn't proven to do that by the above rule.
The FDA is expected to officially approve remdesivir as a treatment any minute now.
Posted on 4/29/20 at 6:28 pm to GOP_Tiger
It would be nice if remdesivir worked better against COVID-19. It appears to offer what I would call a moderate benefit. It's not a magic bullet, not a cure.
But, even so, it's a huge weapon in the battle against a possible 2nd wave this fall. If we can get everyone who comes to the hospital out 31% faster with remdesivir, then the danger of the virus and the strain on our healthcare system can be much reduced.
And, logically, remdesivir would likely have even more success if administered earlier than hospital admission. If old guys in nursing homes, for example, got an IV of it right after a positive test, one would think that the improvement in results would be even greater. The only problem is the likely supply.
As soon as the FDA gives its inevitable permission, I think that Gilead will immediately come under immense pressure to license the drug so that it can be manufactured all over the world in the quantities needed, and I think that will happen, because there's no way that they can ramp-up production themselves to supply the world.
But, even so, it's a huge weapon in the battle against a possible 2nd wave this fall. If we can get everyone who comes to the hospital out 31% faster with remdesivir, then the danger of the virus and the strain on our healthcare system can be much reduced.
And, logically, remdesivir would likely have even more success if administered earlier than hospital admission. If old guys in nursing homes, for example, got an IV of it right after a positive test, one would think that the improvement in results would be even greater. The only problem is the likely supply.
As soon as the FDA gives its inevitable permission, I think that Gilead will immediately come under immense pressure to license the drug so that it can be manufactured all over the world in the quantities needed, and I think that will happen, because there's no way that they can ramp-up production themselves to supply the world.
Posted on 4/29/20 at 7:22 pm to GOP_Tiger
quote:
In real news, though, we finally have a drug that has proven to be an effective treatment
It's an interesting start, but not the indication that really makes a huge impact here. They need to study it in early administration, i.e., ASAP after onset of Sx. If that proves effective, in reducing the need for hospitalization and possibly reducing the duration of viral shedding, then we have a drug that will end this shutdown and mitigate the ongoing economic damage.
Because the economic damage, destruction of small business (middle class), destruction of currencies (inflation), destruction of the incentives that are the glue of our civil society (personal responsibility), is the real pandemic now. As long as this disease of govt overreach and monetary madness continues to grow and metastasize, our chances of emerging from this in a sane world will continue to diminish.
edit: just saw your previous post.
quote:
And, logically, remdesivir would likely have even more success if administered earlier than hospital admission.
Absolutely. Moderate benefit in patients already hospitalized due to respiratory compromise is nice, but not a "game changer".
This post was edited on 4/29/20 at 7:27 pm
Posted on 4/29/20 at 8:56 pm to GOP_Tiger
A certain lab tried to file for a patent for this as a treatment for the Wuhan virus.
https://time.com/5778216/china-patent-coronavirus-drug/
https://time.com/5782633/covid-19-drug-remdesivir-china/
Goes without saying this lab has some inside info on original strains of virus not shared with world.
quote:
The patent application was made on Jan. 21, according to a statement posted on the website of the virology institute in Wuhan, the central Chinese city at the epicenter of the epidemic. Scientists there have found Gilead’s remdesivir, and chloroquine, an 80-year-old malaria drug, “highly effective” in laboratory studies at thwarting the novel coronavirus, they said Tuesday in a paper in the journal Cell Research. The two drugs’ efficacies on humans required further clinical tests, the institute said in the statement.
https://time.com/5778216/china-patent-coronavirus-drug/
quote:
Its stock surged 20% in Tuesday morning trading in Shanghai. While BrightGene said that it intends to license the drug from Gilead, it's move to start manufacturing at this early stage is highly unusual and a potential infringement of the American company’s intellectual property. It comes a week after Chinese researchers filed an application to patent the drug to treat the new coronavirus, a bid that would give China sway over the global use of the therapy to fight the outbreak.
https://time.com/5782633/covid-19-drug-remdesivir-china/
Goes without saying this lab has some inside info on original strains of virus not shared with world.
Posted on 4/29/20 at 9:00 pm to GOP_Tiger
Earlier this story was pushed around
https://www.statnews.com/2020/04/23/data-on-gileads-remdesivir-released-by-accident-show-no-benefit-for-coronavirus-patients/
For some it may depend on whether or not they can let go that this was another treatment Trump said looked promising back in mid March including if any wives murder their husbands with some form of it while blaming Trump. TDS is strong in some.
Article from March 28th
From March 23rd
quote:
antiviral medicine remdesivir from Gilead Sciences failed to speed the improvement of patients with Covid-19 or prevent them from dying, according to results from a long-awaited clinical trial conducted in China. Gilead, however, said the data suggest a “potential benefit.”
https://www.statnews.com/2020/04/23/data-on-gileads-remdesivir-released-by-accident-show-no-benefit-for-coronavirus-patients/
For some it may depend on whether or not they can let go that this was another treatment Trump said looked promising back in mid March including if any wives murder their husbands with some form of it while blaming Trump. TDS is strong in some.
Article from March 28th
quote:https://www.usatoday.com/story/news/2020/03/28/experimental-coronavirus-drug-remdesivir-trump-lauded-again-available/2934583001/
President Donald Trump called the drug, remdesivir, “promising” 10 days ago, though there is no data yet to show whether it is safe and effective at treating COVID-19. It was originally created as a potential treatment for the Ebola and Marburg viruses.
quote:https://news.yahoo.com/touted-by-trump-hydroxychloroquine-and-remdesivir-fail-as-coronavirus-therapy-in-preliminary-studies-185031030.html
Two drugs touted by President Trump as potential game changers in the fight against the coronavirus have shown no benefit for infected patients who take them. A clinical trial conducted in China appears to show that the antiviral drug remdesivir does not help patients with COVID-19 recover...
From March 23rd
quote:https://www.nytimes.com/2020/03/23/health/coronavirus-drugs-remdesivir.html
Over the last week, President Trump has repeatedly referred to remdesivir and other drugs, like two long-used malaria drugs, as potential game-changers, despite pushback by top health officials like Dr. Anthony Fauci, the director of the National Institute of Allergy and Infectious Diseases.
This post was edited on 4/29/20 at 9:24 pm
Posted on 4/29/20 at 9:06 pm to dallastigers
quote:
antiviral medicine remdesivir from Gilead Sciences failed to speed the improvement of patients with Covid-19 or prevent them from dying, according to results from a long-awaited clinical trial conducted in China. Gilead, however, said the data suggest a “potential benefit.”
That study was underenrolled, without enough patients for the results to be statistically significant. But those patients in the Chinese study, like the ones in the new, complete study out today, did recover faster.
Posted on 4/29/20 at 10:45 pm to GOP_Tiger
I asked much earlier about remdesivir -- someone replied with the fact that it's iv only and that the company that made it had the foresight to start the process of production as there's not a ton just hanging around.
So I looked and found this about it: LINK
It appears to be iv only so administration could be a challenge as one place I read said 5 day or 10 day dosing -- that's either a hospital stay or maybe home health?
So I looked and found this about it: LINK
It appears to be iv only so administration could be a challenge as one place I read said 5 day or 10 day dosing -- that's either a hospital stay or maybe home health?
This post was edited on 4/29/20 at 10:47 pm
Posted on 4/29/20 at 11:23 pm to tiger91
quote:
It appears to be iv only so administration could be a challenge as one place I read said 5 day or 10 day dosing -- that's either a hospital stay or maybe home health?
Well, that's not good. I assumed it was available in oral dosing like most other nucleoside analogs. I guess the search goes on for an early treatment unless they can make a pill form or some kind of depot injection.
Posted on 4/30/20 at 6:55 am to tiger91
quote:
maybe home health?
I don't know about that, because of the number of people who have adverse effects to the medicine. I don't think remdesivir is something that could be given to a patient where they can't be monitored afterward. Maybe it could be administered in some nursing homes.
By the way, it wasn't as noticed, but there was another recent study showing that a 5-day treatment had the same effect as 10-day -- which matters a great deal for a drug in such limited supply.
This post was edited on 4/30/20 at 7:00 am
Posted on 4/30/20 at 6:57 am to GOP_Tiger
Hey Scruffy, did you see President Trump's tweet this morning?
quote:
Despite reports to the contrary, Sweden is paying heavily for its decision not to lockdown. As of today, 2462 people have died there, a much higher number than the neighboring countries of Norway (207), Finland (206) or Denmark (443). The United States made the correct decision!
Posted on 4/30/20 at 7:50 am to GOP_Tiger
I don’t follow Trump, nor do I support his decisions through all of this.
I cannot support the action of crashing the economy, signing a stimulus bill that adds $2 trillion+ (at least 2.5x more than Obama’s stimulus) to the debt, purposefully increased UE to over 26 million, bankrupted many small businesses, and then fought against reopening.
Why would I support any actions that have both national and global health, societal, economic, and military consequences on that scale?
I cannot support the action of crashing the economy, signing a stimulus bill that adds $2 trillion+ (at least 2.5x more than Obama’s stimulus) to the debt, purposefully increased UE to over 26 million, bankrupted many small businesses, and then fought against reopening.
Why would I support any actions that have both national and global health, societal, economic, and military consequences on that scale?
Posted on 4/30/20 at 7:58 am to GOP_Tiger
When it’s all said and done, Sweden will have the same deaths per capita as those 3 other countries. Except Sweden will have a stronger economy with no bail out necessary. Good for them.
Posted on 4/30/20 at 8:08 am to GOP_Tiger
quote:
I don't know about that, because of the number of people who have adverse effects to the medicine. I don't think remdesivir is something that could be given to a patient where they can't be monitored afterward. Maybe it could be administered in some nursing homes.
By the way, it wasn't as noticed, but there was another recent study showing that a 5-day treatment had the same effect as 10-day -- which matters a great deal for a drug in such limited supply.
So I'm guessing that this may not be used on every positive case? That could potentially be a whole lot of hospitalizations, although I wound understand the need for monitoring. Would be lovely if they could find something similar to tamiflu that could be taken orally to avoid hospitalizations.
Posted on 4/30/20 at 8:14 am to tiger91
Also, I find it hypocritical that Trump would praise Louisiana which has 1,800 deaths and a population of 4.7 and chastise Sweden less than 24 hours later. Sweden has 2,500 deaths and a population of 10 million. They’re doing better than us. The shutdown in those other socialist countries he listed goes well beyond what we do here.
Page 1088 of 1190
Popular
Back to top
Follow TigerDroppings for LSU Football News