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1 in 4 NFL players have CTE based on study of brains
Posted on 8/25/26 at 11:10 am
Posted on 8/25/26 at 11:10 am
This is a gift article. You can read it for free from the NY Times.
Since the degenerative brain disease known as C.T.E. was first scientifically linked to football about 20 years ago, and as hundreds of former professional football players have been diagnosed with the disease after their deaths, a haunting question has lingered:
Just how many N.F.L. players will end up with C.T.E.?
New data provides a sobering indication: At least one in four of all the people who have played in the N.F.L. might expect to end up with chronic traumatic encephalopathy, according to a study of hundreds of cases over a recent six-year period.
Researchers considered every former N.F.L. player who died from 2016 to 2021. There were 878. Some died in their 20s, some in their 80s, most in between.
LINK
Since the degenerative brain disease known as C.T.E. was first scientifically linked to football about 20 years ago, and as hundreds of former professional football players have been diagnosed with the disease after their deaths, a haunting question has lingered:
Just how many N.F.L. players will end up with C.T.E.?
New data provides a sobering indication: At least one in four of all the people who have played in the N.F.L. might expect to end up with chronic traumatic encephalopathy, according to a study of hundreds of cases over a recent six-year period.
Researchers considered every former N.F.L. player who died from 2016 to 2021. There were 878. Some died in their 20s, some in their 80s, most in between.
LINK
Posted on 8/25/26 at 11:20 am to Ralph_Wiggum
The growing sample size of C.T.E. cases makes for stark realizations. For example, eight members of the 1972 Miami Dolphins, the only undefeated team in modern N.F.L. history, have been diagnosed with C.T.E.
The latest, previously unreported, was Mercury Morris, the speedy halfback who played eight seasons in the N.F.L., struggled with headaches and drug addiction in retirement, and died in 2024 at age 77.
Not all C.T.E. cases belong to long-retired players in their geriatric years. The 2001 New England Patriots, who won the Super Bowl, had seven former players die between the ages of 35 and 50, according to The Boston Globe. At least three were diagnosed with C.T.E., researchers said.
The latest, previously unreported, was Mercury Morris, the speedy halfback who played eight seasons in the N.F.L., struggled with headaches and drug addiction in retirement, and died in 2024 at age 77.
Not all C.T.E. cases belong to long-retired players in their geriatric years. The 2001 New England Patriots, who won the Super Bowl, had seven former players die between the ages of 35 and 50, according to The Boston Globe. At least three were diagnosed with C.T.E., researchers said.
Posted on 8/25/26 at 11:33 am to Ralph_Wiggum
You baws better start getting familiar with the beautiful game.
Posted on 8/25/26 at 11:41 am to sorantable
People such as Amalu and others have distorted the facts and deliberately profited from CTE.
Do I believe there is CTE? Yes. Do I believe that it is an issue? Yes. Is it as widespread as Amalu and some want us to believe? No.
The fact is, the samples they are getting skew their arguments; look up the BU study from around 2016/2017 to see.
Do I believe there is CTE? Yes. Do I believe that it is an issue? Yes. Is it as widespread as Amalu and some want us to believe? No.
The fact is, the samples they are getting skew their arguments; look up the BU study from around 2016/2017 to see.
Posted on 8/25/26 at 11:43 am to sms151t
Aren't modern helmets with holes and slits all over them, plus only tackling 2 feet below the head, going to solve CTE? This is what I was told.
Posted on 8/25/26 at 11:43 am to sms151t
True or false: Football as we know it will not exist in 25 years.
Posted on 8/25/26 at 11:49 am to Ralph_Wiggum
quote:
Just how many N.F.L. players will end up with C.T.E.?

Posted on 8/25/26 at 11:53 am to sorantable
quote:
You baws better start getting familiar with the beautiful game.
There's still CTE risk with soccer.
I loved playing football but it's really not any different than ramming your head into a wall repeatedly. If you saw a kid doing that you'd make him stop.
Posted on 8/25/26 at 11:56 am to Ralph_Wiggum
How does that compare to the regular population? What about other professions like military, other sports, etc.
Posted on 8/25/26 at 12:01 pm to Ralph_Wiggum
Who knew shitty data gives skewed results?
Posted on 8/25/26 at 12:03 pm to sorantable
quote:
True or false: Football as we know it will not exist in 25 years.
Ditka once said that if the NFL was really serious about player safety they would bring back leather helmets, smaller pads, and teach proper tackling technique. Look at the injury rates for rugby players.
Would be kinda cool if you ask me. Might even make the game better.
Posted on 8/25/26 at 12:11 pm to Diseasefreeforall
quote:
There's still CTE risk with soccer.
All sports carry a risk of head injury, but American football is on a level all its own. Don’t be obtuse.
Posted on 8/25/26 at 12:14 pm to UnitedFruitCompany
quote:
Look at the injury rates for rugby players.
What are their CTE rates?
Posted on 8/25/26 at 12:16 pm to Ralph_Wiggum
Funny how they never focus on women’s soccer players with CTE.
Posted on 8/25/26 at 12:18 pm to sorantable
You’re a white male Democrat and want football to end in its current form? Shocker
Posted on 8/25/26 at 12:20 pm to cubsfan5150
quote:
What are their CTE rates?
Have you met those guys? CTE might make them smarter.
I kid, i kid. Lovely folks those Rugby players. Cant imagine its very high given the low speed collisions involved. and the high speed stuff is usually leg tackles from behind, not straight up two, 250 guys, running full speed at each other.
Posted on 8/25/26 at 12:29 pm to UnitedFruitCompany
Corso always said this too
Helmets make their heads weapons
Helmets make their heads weapons
Posted on 8/25/26 at 12:52 pm to CatfishJohn
I wonder how many of us who played sports, but also were outside kids have CTE. I fell enough times riding bikes, climbing trees, roller blading, let alone playing Football and Lacrosse.
Posted on 8/25/26 at 2:22 pm to SoFla Tideroller
Here is a link to the published article. Read it for yourself. I love football, but we can't force people to play it.
Abstract
Objectives To determine the range of possible prevalences of chronic traumatic encephalopathy (CTE) at death among National Football League (NFL) players and examine the association between CTE severity and risk of dementia.
Design Retrospective population based cohort study.
Setting NFL players from the era of hard-shell helmets (post-1949) in the US, including brain donors to the UNITE (Understanding Neurologic Injury and Traumatic Encephalopathy) and UCSF ADRC (University of California, San Francisco Alzheimer’s Disease Research Center) brain banks.
Participants 1712 former NFL players who died during 2008-21, of whom 338 donated their brains for neuropathological evaluation. Personal information and causes of death according to the National Death Index (NDI) were obtained for all NFL players who died during the study period. Neuropathologists masked to clinical and playing histories assessed postmortem CTE diagnosis and stage IV CTE. Clinicians, masked to neuropathological status, reviewed donors’ medical records and informant based clinical histories, to adjudicate a dementia diagnosis.
Main outcome measures The main outcome measures were the minimum (number of donors with CTE/total number of NFL deaths) and maximum (1-(number of donors without CTE/total number of NFL deaths)) CTE prevalence at death during the study period and the six years (2016-21) when brain donation was most frequent. To account for selection pressure of brain donation status, inverse probability weighting was used to estimate the association between stage IV CTE and study clinician diagnosed dementia.
Results Among 1712 NFL players who died, 338 (19.7%) players’ brains were studied, 315 (93.2%) of whom had a diagnosis of CTE; thus, among all 1712 NFL players who died, the possible CTE prevalence at death ranged between 18.5% and 98.7%. The possible prevalence at death during 2016 to 2021, when brain donation was most frequent, ranged between 24.5% and 97.7%. Among brain donors, 104 (30.8%) had stage IV CTE, 202 (59.8%) had study clinician diagnosed dementia (dementia onset: 63.4 years, standard deviation (SD) 12.5; death: 73.1 years, SD 10.5), and 63 (18.6%) had neurodegenerative disease listed as primary cause of death. In donors, stage IV CTE was associated with study clinician diagnosed dementia (risk ratio 1.44, 95% confidence interval 1.16 to 1.78; P<0.001). Only 40.6% of donors (n=82) with study clinician diagnosed dementia had neurodegenerative disease listed as the primary or secondary cause of death.
Conclusions At minimum, nearly a quarter of all former NFL players who died during 2016-21 had CTE neuropathology at death. Among NFL player brain donors, dementia diagnosed based on records before death was common and associated with stage IV CTE.
LINK
Abstract
Objectives To determine the range of possible prevalences of chronic traumatic encephalopathy (CTE) at death among National Football League (NFL) players and examine the association between CTE severity and risk of dementia.
Design Retrospective population based cohort study.
Setting NFL players from the era of hard-shell helmets (post-1949) in the US, including brain donors to the UNITE (Understanding Neurologic Injury and Traumatic Encephalopathy) and UCSF ADRC (University of California, San Francisco Alzheimer’s Disease Research Center) brain banks.
Participants 1712 former NFL players who died during 2008-21, of whom 338 donated their brains for neuropathological evaluation. Personal information and causes of death according to the National Death Index (NDI) were obtained for all NFL players who died during the study period. Neuropathologists masked to clinical and playing histories assessed postmortem CTE diagnosis and stage IV CTE. Clinicians, masked to neuropathological status, reviewed donors’ medical records and informant based clinical histories, to adjudicate a dementia diagnosis.
Main outcome measures The main outcome measures were the minimum (number of donors with CTE/total number of NFL deaths) and maximum (1-(number of donors without CTE/total number of NFL deaths)) CTE prevalence at death during the study period and the six years (2016-21) when brain donation was most frequent. To account for selection pressure of brain donation status, inverse probability weighting was used to estimate the association between stage IV CTE and study clinician diagnosed dementia.
Results Among 1712 NFL players who died, 338 (19.7%) players’ brains were studied, 315 (93.2%) of whom had a diagnosis of CTE; thus, among all 1712 NFL players who died, the possible CTE prevalence at death ranged between 18.5% and 98.7%. The possible prevalence at death during 2016 to 2021, when brain donation was most frequent, ranged between 24.5% and 97.7%. Among brain donors, 104 (30.8%) had stage IV CTE, 202 (59.8%) had study clinician diagnosed dementia (dementia onset: 63.4 years, standard deviation (SD) 12.5; death: 73.1 years, SD 10.5), and 63 (18.6%) had neurodegenerative disease listed as primary cause of death. In donors, stage IV CTE was associated with study clinician diagnosed dementia (risk ratio 1.44, 95% confidence interval 1.16 to 1.78; P<0.001). Only 40.6% of donors (n=82) with study clinician diagnosed dementia had neurodegenerative disease listed as the primary or secondary cause of death.
Conclusions At minimum, nearly a quarter of all former NFL players who died during 2016-21 had CTE neuropathology at death. Among NFL player brain donors, dementia diagnosed based on records before death was common and associated with stage IV CTE.
LINK
This post was edited on 8/25/26 at 2:24 pm
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