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re: Pfizer efficacy down to 42% while FDA standard for safe/effective/approval is 50%

Posted on 8/11/21 at 1:26 am to
Posted by AUstar
Member since Dec 2012
17088 posts
Posted on 8/11/21 at 1:26 am to
Jack Posobiec gives no context, of course. So I dug up the actual study. Here is what it says:

quote:

Both vaccines were highly effective during this study period against SARS-CoV-2 infection (mRNA-1273: 86%, 95%CI: 81-90.6%; BNT162b2: 76%, 95%CI: 69-81%) and COVID-19 associated hospitalization (mRNA-1273: 91.6%, 95% CI: 81-97%; BNT162b2: 85%, 95% CI:73-93%). However, in July, the effectiveness against infection was considerably lower for mRNA-1273 (76%, 95% CI: 58-87%) with an even more pronounced reduction in effectiveness for BNT162b2 (42%, 95% CI: 13-62%).


In other words, Moderna still going strong at 76%. Pfizer seems to be down to 42% against Delta insofar as protecting against infection.

However, they also said this:

quote:

Our observational study highlights that while both mRNA COVID-19 vaccines strongly protect against infection and severe disease, further evaluation of mechanisms underlying differences in their effectiveness such as dosing regimens and vaccine composition are warranted.


As you can see above, Moderna was 91% effective at preventing hospitalization and Pfizer was at 85%. So let's not pretend it's the end of the world. Yes, the efficacy has decreased with Delta, but the beauty of mRNA is they can quickly tweak it for new variants (in like days). They don't have to grow or culture the virus to do this.
Posted by David_DJS
Member since Aug 2005
18170 posts
Posted on 8/11/21 at 1:30 am to
quote:

Yes, the efficacy has decreased with Delta, but the beauty of mRNA is they can quickly tweak it for new variants (in like days). They don't have to grow or culture the virus to do this.

How do they compare to natural immunity?
Posted by geauxturbo
Baton Rouge
Member since Aug 2007
4198 posts
Posted on 8/11/21 at 5:44 am to
quote:

As you can see above, Moderna was 91% effective at preventing hospitalization 


Curious how they determine if it is the vax that is effective at prevetnting hospitalization.
Posted by jimmy the leg
Member since Aug 2007
34882 posts
Posted on 8/11/21 at 5:44 am to
quote:

Yes, the efficacy has decreased with Delta, but the beauty of mRNA is they can quickly tweak it for new variants (in like days).


So boosters for life. Beauty is in the eye of the holder I suppose.

Tell me more about natural immunity. That is, IF you can actually find any info that isn’t either dismissed (like Dr. Catherine O’Neal did as JBE’s mouthpiece), limited in scope, or....seemingly buried.
This post was edited on 8/11/21 at 5:48 am
Posted by theunknownknight
Baton Rouge
Member since Sep 2005
57477 posts
Posted on 8/11/21 at 5:47 am to
The relative risk reduction is what they are reporting and that doesn’t have any real world impact when the actual risk is through the floor in the first place.
This post was edited on 8/11/21 at 8:11 am
Posted by Jack Daniel
In the bottle
Member since Feb 2013
25690 posts
Posted on 8/11/21 at 6:26 am to
So a new shot for each “variant”?
Posted by diat150
Louisiana
Member since Jun 2005
43788 posts
Posted on 8/11/21 at 6:29 am to
quote:

you can see above, Moderna was 91% effective at preventing hospitalization and Pfizer was at 85%.


What is hospitalization % of unvaccinated ?
Posted by OceanMan
Member since Mar 2010
20066 posts
Posted on 8/11/21 at 6:30 am to
quote:

Yes, the efficacy has decreased with Delta, but the beauty of mRNA is they can quickly tweak it for new variants (in like days).


Is that the game plan? Asking people to get jabbed for each variant?

If people oppose getting one or two to talk it’s going to get ugly if it’s multiple per year.
Posted by Landmass
Member since Jun 2013
18227 posts
Posted on 8/11/21 at 7:38 am to
Malta, Gibraltar, Israel, Iceland, and many others all disagree. In these nations, most hospitalized cases are vaccinated. They are also the most vaccinated nations in the world and that corresponds to a huge spike in cases and hospitalizations. I'm tired of having real world examples disprove everything that the US Govt agencies say, yet ignore these real world examples to the contrary.

Meanwhile, Sweden...
Posted by Bourre
Da Parish
Member since Nov 2012
20332 posts
Posted on 8/11/21 at 7:51 am to
quote:

the beauty of mRNA is they can quickly tweak it for new variants


Was indefinite booster shots part of the deal? Once again the credibility of jabbers are thrown out the window
Posted by TenWheelsForJesus
Member since Jan 2018
6785 posts
Posted on 8/11/21 at 9:56 am to
quote:

Yes, the efficacy has decreased with Delta, but the beauty of mRNA is they can quickly tweak it for new variants (in like days). They don't have to grow or culture the virus to do this.


Awesome. Your vaccine passport will need to be a sheet of legal paper by the time the fearmongering is complete.
Posted by GRTiger
On a roof eating alligator pie
Member since Dec 2008
63469 posts
Posted on 8/11/21 at 11:08 am to
quote:

As you can see above, Moderna was 91% effective at preventing hospitalization and Pfizer was at 85%.


The cumulative rate of hospitalizations for people under 40 is 700 per 100,000 confirmed cases in that age group. That's all in since the beginning. So simply being young and healthy has a hospital prevention success rate of 99.3%.

So do we All still need this, or is the 80+% vax rate for the elderly a pretty good figure at this point?
Posted by Barstools
Atlanta
Member since Jan 2016
9515 posts
Posted on 8/11/21 at 2:26 pm to
That says they are effective at reducing hospitalization not effective at stoping the spread or providing immunity.

So, it's not actually a vaccine.
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