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re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***

Posted on 5/29/20 at 7:28 am to
Posted by SloaneRanger
Upper Hurstville
Member since Jan 2014
8092 posts
Posted on 5/29/20 at 7:28 am to
quote:

24,396 total tested for antibodies

9.4% positive rate across the state and all demographics



Any information on what the figure is for the NO area?
Posted by lsupride87
Member since Dec 2007
96699 posts
Posted on 5/29/20 at 7:35 am to
quote:

Any information on what the figure is for the NO area?
They have it, but I am uncertain the breakout by region
Posted by Sasquatch Smash
Member since Nov 2007
24179 posts
Posted on 5/29/20 at 8:54 am to
quote:

24,396 total tested for antibodies

9.4% positive rate across the state and all demographics



When will the methods be posted so buckeye_vol can come in and shite all over it and tell us how wrong it is? Hahaha.



Busting balls, he does do good work, just a perception of him pooping on anything positive in this.
This post was edited on 5/29/20 at 9:22 am
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 5/29/20 at 9:55 am to
More T cell data LINK

quote:

It was remarkable to find that NSP7/13 specific T cells were detected in 9 out of 18 (50%) SARS CoV 1/2 unexposed donors, despite the fact that our analysis was performed with peptides that cover only 10% (684aa) of the ORF - 1 proteome (7096aa)

In coronavirus infected cells, the ORF coded proteins are necessary for the formation of the viral replicase transcriptase complex in which viral replication and transcription occur. Therefore, an ORF specific T cell can be envisioned to abort viral production in infected cells by lyses of SARSCoV 2 infected cells even before the formation of mature virions.
This post was edited on 5/29/20 at 9:57 am
Posted by klrstix
Shreveport, LA
Member since Oct 2006
3219 posts
Posted on 5/29/20 at 11:29 am to
quote:

More T cell data LINK



So.. not even being technically proficient enough to be considered a novice...

When I read your quote it seems as though what it is saying is that they think T Cells are disrupting the Virus before the process of infection fully matures...

is that correct??
Posted by Bullfrog
Institutionalized but Unevaluated
Member since Jul 2010
56596 posts
Posted on 5/29/20 at 11:34 am to
They are defending the cell walls and preventing the virus from entry, from what I’m gathering.

Then it’s pooped out and ends up in the sewage system.

Or all over the people pooping in bed in nursing homes and spreads there from the cleanup activities.
This post was edited on 5/29/20 at 11:36 am
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 5/29/20 at 11:46 am to
quote:

When I read your quote it seems as though what it is saying is that they think T Cells are disrupting the Virus before the process of infection fully matures...


quote:

They are defending the cell walls and preventing the virus from entry, from what I’m gathering.


Not entirely.

Just a little groundwork... Viruses work by hijacking a cell and using its machinery to make copies of itself to that it can spread and multiply.

This is more speculation than fact in the article, but how I interpret the quote is that the cell gets infected by the virus but the T cell kills the cell and stops the virus from being able to use the cell to make copies of itself. effectively halting the spread of the infection.

Why do i think this is important? Because possibly these patients could stop the virus from spreading without having detectable antibodies in their blood. This could be happening on a local level in the nasal passages and throat.

sidenote: that is one of the main functions of T cells... to kill virus infected cells. The question is can they do it before the infection "takes off", thus giving some sort of immunity.

side sidenote: 50% of people that never had COVID had these T cells!
This post was edited on 5/29/20 at 11:50 am
Posted by Jim Rockford
Member since May 2011
98697 posts
Posted on 5/29/20 at 12:14 pm to
People are throwing out their stimulus payments because they think it's junk mail LINK
Posted by Whiznot
Albany, GA
Member since Oct 2013
7024 posts
Posted on 5/29/20 at 12:19 pm to
A Cambridge team of geneticists led by Peter Forster reported that they were able to sequence mutations in order to trace the virus' origin in humans. Those scientists reported that the earliest known human infection occurred in China well South of Wuhan.

I've wondered whether China was trying to use a biological agent against Hong Kong protestors. I think that's highly unlikely but still I wonder.
Posted by buckeye_vol
Member since Jul 2014
35252 posts
Posted on 5/29/20 at 12:56 pm to
quote:

A Cambridge team of geneticists led by Peter Forster reported that they were able to sequence mutations in order to trace the virus' origin in humans. Those scientists reported that the earliest known human infection occurred in China well South of Wuhan.
Do you have a link to that? I can see how they can link trace it back to a person who comes from an group that is predominant in a specific region of the world, but I don’t see how you can determine that the person contracted the virus in that specific region.

For example, (SPOILER ALERT) in the movie Contagion, Gwyneth Paltrow‘s character was Patient Zero and she was from Minneapolis (interesting given current events). But the zoonotic transmission (bat and pig to human) occurred in Macau. So if they were able to genetically trace it back to her, that wouldn’t tell us where it started.

So given the outbreak in Wuhan, it seems like regardless of how, when, and why it happened, that the this was the original mass outbreak location.
This post was edited on 5/29/20 at 1:00 pm
Posted by Sasquatch Smash
Member since Nov 2007
24179 posts
Posted on 5/29/20 at 12:57 pm to
quote:

People are throwing out their stimulus payments because they think it's junk mail


My aunt almost did.
Posted by klrstix
Shreveport, LA
Member since Oct 2006
3219 posts
Posted on 5/29/20 at 1:11 pm to

Thanks
Posted by Ronaldo Burgundiaz
NWA
Member since Jan 2012
6588 posts
Posted on 5/29/20 at 4:50 pm to
Interesting info from CDC's "abnormal, unclassified" causes of death compared to previous years.



If you presume the jump in abnormal causes of death shown in the chart to be covid-related, it would imply that it has been circulating in the US since at least November.
Posted by Ronaldo Burgundiaz
NWA
Member since Jan 2012
6588 posts
Posted on 5/29/20 at 5:10 pm to
RE: Efficacy of lockdowns / shelter-in-place

Tweet by ABC's medical lead, Eric Strauss (also Tulane grad):

JUST IN: @ABC looked at 21 states that eased restrictions May 4 or earlier & found no major increase in hospitalizations, deaths or % of people testing positive in any of them. [SC, MT, GA, MS, SD, AR, CO, ID, IA, ND, OK, TN, TX, UT, WY, KS, FL, IN, MO, NE, OH] via @AMitrops

LINK

He hasn't posted the data, waiting on that.

Even the news media is catching on. Louisiana, its time to join the free states.

Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 5/29/20 at 5:14 pm to
Yea that’s interesting. I’m not sure if it’s anything more than a correlation because I would think any COVID death before COVID was known would have just been classified as suspected flu or unknown pneumonia

It wouldn’t be good news for the antibody studies, unless we think there are cases that the antibody tests are missing, that’s possible.

I read a few articles recently that said the mortality rate in France is now lower than the average over the last 2 weeks. It will be interesting to see if most places follow that trend after this wave.
Posted by buckeye_vol
Member since Jul 2014
35252 posts
Posted on 5/29/20 at 5:59 pm to
quote:

states that eased restrictions May 4 or earlier
quote:

OH
Huh?
This post was edited on 5/29/20 at 6:00 pm
Posted by Ronaldo Burgundiaz
NWA
Member since Jan 2012
6588 posts
Posted on 5/29/20 at 6:17 pm to
According to Google, OH went into Phase 1 on May 1?
Posted by buckeye_vol
Member since Jul 2014
35252 posts
Posted on 5/29/20 at 6:23 pm to
quote:

According to Google, OH went into Phase 1 on May 1?
Yeah. Like dental and vet appointments. It wasn’t until the 12th that things really opened up.
quote:

Friday, May 1: Hospital, medical, dental and veterinary services that don't require an overnight hospital stay.
quote:

Saturday, May 2: Retail businesses that have been closed can open for curbside pickup, delivery and appointment-only shopping limited to 10 customers at a time.
quote:

Monday, May 4: Construction, distribution, manufacturing, offices.
quote:

Tuesday, May 12: Consumer, retail and service businesses.
Posted by WaWaWeeWa
Member since Oct 2015
15714 posts
Posted on 5/29/20 at 7:03 pm to
It’s a pointless argument.
We can’t stay locked down regardless of what the outcome will be.
Posted by buckeye_vol
Member since Jul 2014
35252 posts
Posted on 5/29/20 at 7:59 pm to
quote:

It’s a pointless argument.
We can’t stay locked down regardless of what the outcome will be.
I agree. I’m just saying that Ohio was not an early opener in any substantive way.
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