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Wait a second..so PCR testing couldn't tell the difference between covid and the flu?

Posted on 7/25/21 at 11:27 pm
Posted by Huey Lewis
BR
Member since Oct 2013
4643 posts
Posted on 7/25/21 at 11:27 pm
CDC website: https://www.cdc.gov/csels/dls/locs/2021/07-21-2021-lab-alert-Changes_CDC_RT-PCR_SARS-CoV-2_Testing_1.html?fbclid=IwAR3K0L_-rYe69v2Oau6En4Uhyk3a1nTtwFZ9fSh0S90_lwBwo58VB8hGqz8

quote:

fter December 31, 2021, CDC will withdraw the request to the U.S. Food and Drug Administration (FDA) for Emergency Use Authorization (EUA) of the CDC 2019-Novel Coronavirus (2019-nCoV) Real-Time RT-PCR Diagnostic Panel, the assay first introduced in February 2020 for detection of SARS-CoV-2 only. CDC is providing this advance notice for clinical laboratories to have adequate time to select and implement one of the many FDA-authorized alternatives.

Visit the FDA website for a list of authorized COVID-19 diagnostic methods. For a summary of the performance of FDA-authorized molecular methods with an FDA reference panel, visit this page.

In preparation for this change, CDC recommends clinical laboratories and testing sites that have been using the CDC 2019-nCoV RT-PCR assay select and begin their transition to another FDA-authorized COVID-19 test. CDC encourages laboratories to consider adoption of a multiplexed method that can facilitate detection and differentiation of SARS-CoV-2 and influenza viruses. Such assays can facilitate continued testing for both influenza and SARS-CoV-2 and can save both time and resources as we head into influenza season. Laboratories and testing sites should validate and verify their selected assay within their facility before beginning clinical testing.



In February 2020 the FDA granted emergency use authorization for PCR testing to test for covid.

Now they're rescinding the use of the test for covid because it can't differentiate between covid and the flu, and instead recommend the use of different testing methods.

How many positive PCR tests have their been in the last year and half? How many of them were actually the flu? How many "confirmed" covid case deaths were actually the flu?

And yet we've been told the reason flu cases and flu deaths were so low last year was because masks and social distancing stopped the flu.



Posted by goldennugget
Hating Masks
Member since Jul 2013
24514 posts
Posted on 7/25/21 at 11:31 pm to
PCR testing was set up to generate a lot of false positives by design to inflate case numbers to use for fear mongering to push mail in voting, eliminating poll watchers and other schemes designed to influence the 2020 election.

Now this is backfiring on them because its hard to sell the vaccine effectiveness with these sensitive tests generating false positives.
Posted by BuckyCheese
Member since Jan 2015
48840 posts
Posted on 7/25/21 at 11:32 pm to
How many flu deaths have we had the past year and a half?


There's your answer.
Posted by tiger91
In my own little world
Member since Nov 2005
36703 posts
Posted on 7/25/21 at 11:33 pm to
If I'm not mistaken, Gates has somethign to do with the new testing swabs/methods???
Posted by Korkstand
Member since Nov 2003
28703 posts
Posted on 7/25/21 at 11:44 pm to
quote:

CDC encourages laboratories to consider adoption of a multiplexed method that can facilitate detection and differentiation of SARS-CoV-2 and influenza viruses.
quote:

Now they're rescinding the use of the test for covid because it can't differentiate between covid and the flu, and instead recommend the use of different testing methods.
That's not what that sentence means. You even quoted this part:
quote:

the CDC 2019-Novel Coronavirus (2019-nCoV) Real-Time RT-PCR Diagnostic Panel, the assay first introduced in February 2020 for detection of SARS-CoV-2 only
In other words, the old test detected covid only. Now they recommend tests that also detect flu in a single test so that multiple tests are not required to determine whether a person has covid or flu.


Posted by CamdenTiger
Member since Aug 2009
62370 posts
Posted on 7/26/21 at 12:00 am to
Anyone wonder why there was no flu last year? Knew it would be fixed after the election
Posted by HailToTheChiz
Back in Auburn
Member since Aug 2010
48894 posts
Posted on 7/26/21 at 12:04 am to
So why were they not doing this before? If they could differentiate between flu and covid, then they intentionally chose to combine the two to inflate cases
Posted by Winston Cup
Dallas Cowboys Fan
Member since May 2016
65489 posts
Posted on 7/26/21 at 12:05 am to
I feel like we knew this, but it deserves being said out loud
Posted by Korkstand
Member since Nov 2003
28703 posts
Posted on 7/26/21 at 12:18 am to
quote:

So why were they not doing this before?
Probably because it takes time to develop a multiplexed test, and they are also likely more expensive per test. However if two distinct tests are commonly used together on the same patient, it makes sense to combine them to bring costs down.
quote:

If they could differentiate between flu and covid, then they intentionally chose to combine the two to inflate cases
Again, the covid tests never returned positive in the case of flu. It's just they wouldn't indicate flu, because it was a test for covid only. The tests are specific to what they test for.

In case it's still not clear, the covid test that is no longer recommended does not confuse flu for covid, it just does not test for flu at all. It indicates covid or not covid. The currently recommended tests check for both flu and covid, and of course differentiate between them. This is recommended for practical and cost/time-saving reasons so that two tests are no longer needed.
Posted by RobbBobb
Matt Flynn, BCS MVP
Member since Feb 2007
27877 posts
Posted on 7/26/21 at 12:29 am to
quote:

In other words, the old test detected covid only

Not surprising that yet again you are wrong. The panel supplied to labs wanting to get in the rapid test business actually tested for 2 diseases: the original COVID strain and MERS
quote:

The panel contains one heat-inactivated SARS-CoV-2 strain and one heat-inactivated MERS-CoV strain in cell culture media. The panel is composed of five tubes (T1 to T5): T1 contains the SARS-CoV-2 strain (2019-nCoV/USA-WA1/2020) at a concentration of ~1.8x108 RNA NAAT detectable units/mL (NDU/mL); T2, T3, T4, and T5 contain blinded samples, meaning that, although the FDA knows the concentration, the developer testing the samples does not.

And heres the fun part
quote:

Recent mutations reported for SARS-CoV-2 (e.g., D614G), which may impact molecular testing, are not included.

But heres the kicker, as we go into an election year
quote:

Such assays can facilitate continued testing for both influenza and SARS-CoV-2 and can save both time and resources as we head into influenza season

Why are they expecting an influenza season? We didnt have one last year?
Posted by Korkstand
Member since Nov 2003
28703 posts
Posted on 7/26/21 at 12:46 am to
quote:

Not surprising that yet again you are wrong.
Not surprising that yet again you prove to be one of the biggest dumbasses I've ever run across.
quote:

The panel supplied to labs wanting to get in the rapid test business actually tested for 2 diseases: the original COVID strain and MERS
No, dipshit. MERS was added to the panel in various concentrations unknown to the test developers so that they could show how specific to covid their tests are. It's to determine cross-reactivity with MERS, which is much more similar to the covid virus than are influenza strains. If their tests react to covid and NOT MERS, then they damn sure won't react to flu.
Posted by BurntOrangeMan
Dallas TX
Member since May 2021
5628 posts
Posted on 7/26/21 at 1:51 am to
Dr. Kary Mullis (PCR inventor) said it wasn't designed with any consideration to what they are using for today and it is not a legitimate test ID'ing SARS.

On top of that they cranked up the cycle magnification in such a way it is barely 50% accurate and in some countries a 40 count test can be as low as three percent accurate.

I'll find a link to a journal report tmrw and post it.
Posted by Crimson Wraith
Member since Jan 2014
24724 posts
Posted on 7/26/21 at 1:52 am to
Posted by Geauxgurt
Member since Sep 2013
10443 posts
Posted on 7/26/21 at 2:34 am to
This is a specific RT-PCR system that was used initially. While flawed, it only looked for Covid-19.

Since the initial authorization, better tools have been developed including other RT-PCR setups and primers. Those are fully approved and are now being suggested in place of the original version.

The recommendation part about multiplexing is to use the same sample to screen for both multiple strains of Covid and also influenza. It helps make sure of two things: 1) numbers of both virus families are clearly identified when possible and 2) appropriate treatments are given when possible.

None of this is saying all the RT-PCR tests were an issue, but that better versions re now available and recommended. The false positives have a lot more to do with unrealistic Ct values for cutoffs which are too high and counting minuscule amounts of the DNA being present as a positive. That was the biggest flaw with these tests.

In the end, this release can be looked at and twisted to fit each persons agenda, but there was not some major conspiracy to ramp up numbers of cases with false positives.
Posted by omegaman66
greenwell springs
Member since Oct 2007
22772 posts
Posted on 7/26/21 at 3:30 am to
quote:

Probably because it takes time to develop a multiplexed test, and they are also likely more expensive per test.


You are so wrong. Why do you say things that you know are wrong. You know your bs answer is bs but you come here and type it out as if you can change reality just by repeating excuses.

You are lying to yourself and to everyone here.
Posted by Stealth Matrix
29°59'55.98"N 90°05'21.85"W
Member since Aug 2019
7790 posts
Posted on 7/26/21 at 3:33 am to
Yeah... Someone needs to go to prison for this "pandemic"
Posted by BuckyCheese
Member since Jan 2015
48840 posts
Posted on 7/26/21 at 5:10 am to
quote:

You are so wrong. Why do you say things that you know are wrong. You know your bs answer is bs but you come here and type it out as if you can change reality just by repeating excuses.

You are lying to yourself and to everyone here.


It's what he does. Not the first time and won't be the last.
Posted by Purple Spoon
Hoth
Member since Feb 2005
17769 posts
Posted on 7/26/21 at 5:41 am to
quote:

can be looked at and twisted to fit each persons agenda


Nah. I think it is pretty clear.


Posted by shell01
Marianna, FL
Member since Jul 2014
793 posts
Posted on 7/26/21 at 6:26 am to
Korkstand is absolutely right here and as some of us have tried to explain on the half dozen other threads on this announcement.

The CDC doesn't approve or revoke approval of tests. That responsibility sits with the FDA.

The CDC is voluntary pulling the specific RT-PCR test that it developed at the start of the pandemic and offered to other labs. The announcement is just a heads up to labs that they should find another test. Preferably one that can positively identify multiple respiratory viruses including COVID and influenza.

The CDC RT-PCR will only give you a yes or no for COVID. Patient presents with fever, malaise, dyspnea ..you run this test and it says it's not COVID well you need to take another sample and run another test. With a multiplex test instead of just a "negative for COVID" you might get a positive for influenza B.
Posted by ChineseBandit58
Pearland, TX
Member since Aug 2005
42517 posts
Posted on 7/26/21 at 6:28 am to
quote:

yet we've been told the reason flu cases and flu deaths were so low last year was because masks and social distancing stopped the flu.


yep - I hear that constantly - standard response and it usually gets the recommendation to "always wear the mask - it prevents the flu too."

Just have to walk away from those arguments/
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