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Message
re: Letter from FDA to physicians on acetaminophen use
Posted on 9/24/25 at 12:17 pm to LSUTANGERINE
Posted on 9/24/25 at 12:17 pm to LSUTANGERINE
They still give the basic objective to LIMIT usage in pregnancy.
No one can conclusively say so. There is always a ying to the yang disclaimer.
No one is going to lose money on the drug choice to break fevers. Just like no one lost money saying do not take motrin while pregnant.
Should geriatric people inquire to Tylenol Arthritis take two? With an unusually high dosage harming anything? Or does the quality of life outweigh someone already old?
Much like a 90 year old geriatric born with polio in pain always taking opioid's-worrying about addiction?
RFK's point is the people making decisions of tylenol versus motrin in pregnancy-- Can't always be trusted to share any absolutes much less brief studies over their palms always getting greased.
No one can conclusively say so. There is always a ying to the yang disclaimer.
No one is going to lose money on the drug choice to break fevers. Just like no one lost money saying do not take motrin while pregnant.
Should geriatric people inquire to Tylenol Arthritis take two? With an unusually high dosage harming anything? Or does the quality of life outweigh someone already old?
Much like a 90 year old geriatric born with polio in pain always taking opioid's-worrying about addiction?
RFK's point is the people making decisions of tylenol versus motrin in pregnancy-- Can't always be trusted to share any absolutes much less brief studies over their palms always getting greased.
Posted on 9/24/25 at 12:18 pm to Ace Midnight
quote:
Meh. Like the man said, "There is no downside." Probably too strong, but way closer to the truth than, "There is no risk in taking these."
Well, at the population level, phrasing is critical.
As has been noted, there are two obvious downsides to me with this tylenol hysteria: 1) people may now not take it when the benefits outweigh the risks (fever is the easy example, depending on how high and timing of course) and 2) people may now take an alternative without realizing it is actually less safe, but hasn't been all over the media as being "dangerous" (i.e. ibuprofen).
Even if its not a high percentage, even low percentages matter at the population level.
Posted on 9/24/25 at 12:19 pm to LSUTANGERINE
Yo. moron. A study to establish a causal relationship would require a placebo-controlled study and an 8-10 year follow-up to see whose kids develop a neurological disorder.
We are talking about an OTC analgesic. There isn't an IRB in the world that would approve such a study, not even on Chinese prisoners.
Jeebus.

We are talking about an OTC analgesic. There isn't an IRB in the world that would approve such a study, not even on Chinese prisoners.
Jeebus.
This post was edited on 9/24/25 at 12:23 pm
Posted on 9/24/25 at 12:21 pm to SallysHuman
quote:
Nice try at the gotcha.
Its not a gotcha, and you proved my point...
quote:
you surely know other otc pain relievers are also not recommended for use in pregnancy.
Is ibuprofen just "not recommended" or is there a stronger stance on its using during pregnancy?
I can lead you to water, but can't make you drink.
Posted on 9/24/25 at 12:24 pm to onmymedicalgrind
quote:
I can lead you to water, but can't make you drink.
Lead yourself to water.
You are a prime example on this board of a fart sniffing medical professional more interested in gatekeeping than discussing. I've been down the rabbit hole with your insufferable self. No thanks.
Posted on 9/24/25 at 12:24 pm to Wildcat1996
the one with the 1980's pager wants a gotcha on Trump/RFK so bad
hey tangerine pager from the 80's, have your wife/GF/SO take all the tylenol they want in the second and last trimester. no one is forcing anything.
your pager is going off call 910-867-5309
Not making fun...medical professionals had these but so did helicopter rich kids and drug dealers.
hey tangerine pager from the 80's, have your wife/GF/SO take all the tylenol they want in the second and last trimester. no one is forcing anything.
your pager is going off call 910-867-5309
Not making fun...medical professionals had these but so did helicopter rich kids and drug dealers.
This post was edited on 9/24/25 at 12:28 pm
Posted on 9/24/25 at 12:24 pm to LSUTANGERINE
quote:
Trump should have never been in front of the microphone
I have to agree. It is hard to square what he said and what was actually directed by the FDA. It is problematic.
Posted on 9/24/25 at 12:27 pm to SallysHuman
quote:
You are a prime example on this board of a fart sniffing medical professional more interested in gatekeeping than discussing. I've been down the rabbit hole with your insufferable self. No thanks.
Aww, Sensitive Sally.
Posted on 9/24/25 at 12:28 pm to LSUTANGERINE
I dont believe a thing the FDA says.
Posted on 9/24/25 at 12:30 pm to Mid Iowa Tiger
quote:
Holy shite. That’s really what you get from that? I read it as - only use it when absolutely needed because there is mounting evidence it creates more issues than it solves.
Acetominiphen is touted as ultra safe but when I developed some arthritic issues in my neck and was taking it routinely my wife told me to stop. Her friend’s husband had just died from regular tylenol use for back pain. It killed his liver and eventually killed him. I also found out the hard way that if you take the max recommended dose every day for about two wks you get rebound headaches when it wears off. I was waking up at 2AM to take another dose.
Posted on 9/24/25 at 12:30 pm to LSUTANGERINE
"casual relationship" ???
Posted on 9/24/25 at 12:31 pm to SallysHuman
This is one of those things that should have been put out in the normal course and scope of FDA activities
“hey we are recommending doctors discuss that tylenol has links to neurological defects especially when abused”
But RFK Jr told us months ago he’s figure out what’s causing autism by september, and now we have a press conference with the actual president talking about it. That’s overdone
“hey we are recommending doctors discuss that tylenol has links to neurological defects especially when abused”
But RFK Jr told us months ago he’s figure out what’s causing autism by september, and now we have a press conference with the actual president talking about it. That’s overdone
Posted on 9/24/25 at 12:32 pm to how333
quote:
"casual relationship" ???
Causal
quote:
causal/kô'z?l/
adjective Of, involving, or constituting a cause.
"a causal relationship between scarcity of goods and higher prices."
Indicative of or expressing a cause.Relating to a cause or causes; inplying or containing a cause or causes; expressing a cause; causative.
Similar: causative
Posted on 9/24/25 at 12:32 pm to LSUTANGERINE
quote:
acetaminophen is taken chronically throughout pregnancy to childbirth
Nobody should be doing this chronically
Posted on 9/24/25 at 12:35 pm to Wildcat1996
You’re right that we can’t and won’t do a placebo trial on pregnant women but that’s not the only way medicine figures out cause and effect. Thalidomide, Vioxx, even smoking were all nailed down without randomized trials. The process involves multiple lines of evidence - epidemiology, case reports, lab studies, dose-response patterns, etc. until the picture is clear. That’s why the bar for saying causal harm is high, and why a single suggestive study isn’t enough to overturn decades of safe use.
Posted on 9/24/25 at 12:35 pm to SammyTiger
quote:
This is one of those things that should have been put out in the normal course and scope of FDA activities
If it had... it would not have made news or raised awareness in the population of pregnant and soon to be pregnant mothers.
It isn't a bad thing that this information and these changes have garnered so much attention.
The fact that Trump was headlining it and made it over the top (Yes, it was certainly over the top) is the ONLY reason anyone in the regular world is even discussing it at all.
This post was edited on 9/24/25 at 12:36 pm
Posted on 9/24/25 at 12:37 pm to BBONDS25
quote:
you people are absolutely insane.
And getting worse. They are collectively losing what little of their minds they have left.
The desperation is is comical to watch.
Posted on 9/24/25 at 12:39 pm to SallysHuman
quote:
If it had... it would not have made news or raised awareness in the population of pregnant and soon to be pregnant mothers.
Thank you, St. Donald Trump! Because of him, pregnant women will now finally start consulting their doctors before they take medication!
Some might even seek pre-natal care! All thanks to Saint Don
It’s truly a miracle a single healthy baby was ever born before this week.
This post was edited on 9/24/25 at 12:42 pm
Posted on 9/24/25 at 12:40 pm to 4cubbies
quote:
Thank you, St. Donald Trump! Because of him, pregnant women will now finally start consulting their doctors before they take medication!
Hey, if it saves one life!
Posted on 9/24/25 at 12:40 pm to SammyTiger
This is right on. Most real safety updates come through drug labeling changes or medical society guidance. They’re boring by design - because they’re meant to inform doctors, not capture news cycles. When it’s rolled out like breaking news, it warps how the public hears it.
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