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re: Ozempic holds promise in treating Alzheimers disease

Posted on 8/9/24 at 10:37 pm to
Posted by G Vice
Lafayette, LA
Member since Dec 2006
13154 posts
Posted on 8/9/24 at 10:37 pm to
I have a friend who is a neurologist who is also board certified in sleep medicine, and he told me that for people who use Benadryl daily as a sleep aid, there is a four-fold increase in early-onset dementia.

This can be quite concerning for many people who have been using Benadryl in this way for a while.

We didn't get into the specifics when he told me that, so I don't have supporting pathophysiology to bring to this thread at this time.
Posted by LSUA 75
Colfax,La.
Member since Jan 2019
4640 posts
Posted on 8/10/24 at 5:56 am to
“I’ve looked for a lot of things to blame for the disease,but this is a first”

Well it’s been out for a few years that anticholinergic drugs are associated with dementia.
That’s chronic use,not occasional use.
Benadryl crosses the brain blood barrier,is why it causes drowsiness.

A friend of mine told me when he was 40 he took Tylenol PM every night for sleep.He was diagnosed with dementia at 59.
He had been showing signs a few years before that,his memory had gotten very bad .He was a cabinet maker and he started botching up his jobs.He started getting lost driving places.
Wife took him to a neurologist where he was officially diagnosed.

Posted by HighRoller
Baton Rouge
Member since Nov 2011
5389 posts
Posted on 8/10/24 at 6:31 am to
quote:

Ozemempic has the same results as a healthy diet and moderate movement


Not sure you could be more wrong.
Posted by SomethingLikeA
Member since Jul 2013
1220 posts
Posted on 8/10/24 at 6:32 am to
quote:

Not sure you could be more wrong.


Lol what could go wrong with his line of thinking.

I wish people could move 5% more and eat 5% less. The majority of people would see amazing health benefits. I understand there are outliers with certain medical conditions etc.
Posted by CoachChappy
Member since May 2013
34082 posts
Posted on 8/10/24 at 7:07 am to
quote:

Many European countries are referring to Alzheimer’s as Type 3 diabetes.

Look at the explosion of Alzheimer’s diagnoses and the proliferation of processed foods. I’ve read studies where Alzheimer’s patients respond very well to low carbohydrate diets. Lower the sugar intake and brain function improves. Amazing isn’t it?!
Posted by mmcgrath
Indianapolis
Member since Feb 2010
37012 posts
Posted on 8/10/24 at 7:28 am to
quote:

Ozempic holds promise in treating Alzheimers disease
I think that was the original purpose of the drug.
Posted by dukesilver72
Texas
Member since Feb 2015
1145 posts
Posted on 8/10/24 at 7:50 am to
I thought statins like cholesterol drugs played a bad part In Alzheimer’s as well.
Posted by N2cars
Close by
Member since Feb 2008
37916 posts
Posted on 8/10/24 at 7:53 am to
Well, if you use it daily, it stops working after about a month. That's fact, and it is true of all OTC sleep aids.




Posted by N2cars
Close by
Member since Feb 2008
37916 posts
Posted on 8/10/24 at 8:01 am to
From MedScape, Mar 12th 2024:

A new study provides more evidence that sildenafil (Viagra) which is used to treat erectile dysfunction (ED) may help protect against Alzheimer's disease (AD).

The large real-world analysis of patient data from two databases showed a 30%-54% reduced prevalence in AD among patients who took sildenafil (Viagra) than those who did not, after adjusting for potential confounding factors.

This observation was further supported by mechanistic studies showing decreased neurotoxic protein levels in brain cells exposed to the phosphodiesterase type 5 inhibitor (PDE5i).



This is the medicine I've seen that actually shows some promise as a preventative.


I get a lot of articles like this in my feed b/c of my interest in Alzheimer's and metastatic breast cancer.

More strides are being made in MBC pharmaceutical research; it's amazing, but can't get here quickly enough.
Posted by F1y0n7h3W4LL
Below I-10
Member since Jul 2019
3598 posts
Posted on 8/10/24 at 8:03 am to
quote:

frick those people when people NEED it to lose weight.


I think your sarcasm was lost on the masses.
Posted by rintintin
Life is Life
Member since Nov 2008
16964 posts
Posted on 8/10/24 at 8:11 am to
quote:

Obviously without big lifestyle interventions that aren’t available for the mass pop., .


What does this even mean?

quote:

people struggle to change


Correct, and the remedy is always take a drug.

Look I'm all for Ozempic for the obese who just can't manage to change their lifestyle. But it's getting too mainstream where everyone who wants to lose their gut seems to champion it. These things never end well.
Posted by SteelerBravesDawg
Member since Sep 2020
43337 posts
Posted on 8/10/24 at 8:26 am to
quote:

frick those people when people NEED it to lose weight.

Melt, fatass.
Posted by Zakatak
Member since Nov 2011
464 posts
Posted on 8/10/24 at 8:37 am to
quote:

Lower the sugar intake and brain function improves.


What add to the difficulty is the disease causes an increase in sugar craving for the patient. But it is definitely related.
Posted by Lsupimp
Ersatz Amerika-97.6% phony & fake
Member since Nov 2003
85274 posts
Posted on 8/10/24 at 8:39 am to
People HATE it with a white hot intensity when obese people take effective weight loss medications. It’s been interesting to observe.

I always keep this stat about obesity in my mind: If you have HIV and take medication your life span is normal. If you have diabetes and take medications your life span is minus 14.

Anything that helps people lose the weight, avoid diabetes and ditch the high blood pressure/ diabetes/ statins etc sounds like a win to me.
Posted by CAD703X
Liberty Island
Member since Jul 2008
91343 posts
Posted on 8/10/24 at 9:00 am to
quote:

People HATE it with a white hot intensity when obese people take effective weight loss medications. It’s been interesting to observe.

The OT: gross this woman on my flight/sitting next to me at lunch/walking down the street is so disgusting look how fat and why do I have to look at these people, Americans are too fat they should do something about it

Also the OT: damn I hate all these people who are no longer fat who used a drug to do it. I hope they die from that treatment.
This post was edited on 8/10/24 at 9:01 am
Posted by SteelerBravesDawg
Member since Sep 2020
43337 posts
Posted on 8/10/24 at 9:02 am to
Nobody does hypocrisy like tOT.
Posted by LouisianaLady
Member since Mar 2009
82716 posts
Posted on 8/10/24 at 9:41 am to
quote:

Anyone that needs, ozempik is fat, and lazy even if, they aren’t fat yet. No one should be allowed to live, fat, even if they can’t remember. 96 hour, water, fasting is so easy.



What is happening here? You're not normal Liz. Her screenname is liz18lsu.

And your name doesn't even come up in the member list.

Posted by CAD703X
Liberty Island
Member since Jul 2008
91343 posts
Posted on 8/10/24 at 11:44 am to
quote:

What is happening here? You're not normal Liz. Her screenname is liz18lsu.

And your name doesn't even come up in the member list.


Yeah something's fricky here
Posted by LifeTimeTiger2
Member since Apr 2017
493 posts
Posted on 8/10/24 at 12:17 pm to
No frick you
Posted by Penrod
Member since Jan 2011
52038 posts
Posted on 8/10/24 at 12:44 pm to
quote:

Being overweight is a risk factor in over 200 diseases, so it will be prescribed for all of them eventually

Bingo!
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