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Long-Term Space Exposure Alters DNA

Posted on 3/15/18 at 9:19 am
Posted by bountyhunter
North of Houston a bit
Member since Mar 2012
6336 posts
Posted on 3/15/18 at 9:19 am
This is pretty interesting.
https://www.nasa.gov/feature/nasa-twins-study-confirms-preliminary-findings

quote:

The Twins Study brought ten research teams from around the country together to accomplish one goal: discover what happens to the human body after spending one year in space. NASA has a grasp on what happens to the body after the standard-duration six-month missions aboard the International Space Station, but Scott Kelly’s one-year mission is a stepping stone to a three-year mission to Mars.

Scott’s telomeres (endcaps of chromosomes that shorten as one ages) actually became significantly longer in space. While this finding was presented in 2017, the team verified this unexpected change with multiple assays and genomics testing. Additionally, a new finding is that the majority of those telomeres shortened within two days of Scott’s return to Earth.

Another interesting finding concerned what some call the “space gene”, which was alluded to in 2017. Researchers now know that 93% of Scott’s genes returned to normal after landing. However, the remaining 7% point to possible longer term changes in genes related to his immune system, DNA repair, bone formation networks, hypoxia, and hypercapnia.


This post was edited on 3/15/18 at 9:20 am
Posted by RidiculousHype
St. George, LA
Member since Sep 2007
10207 posts
Posted on 3/15/18 at 9:21 am to
The fountain of youth has been in space this whole time
Posted by theunknownknight
Baton Rouge
Member since Sep 2005
57366 posts
Posted on 3/15/18 at 9:27 am to
Definition of spaced out
Posted by mailman
Houston
Member since Jul 2009
6143 posts
Posted on 3/15/18 at 9:29 am to
That was only one year in space, no telling what decades of exposure would do.
Posted by RJL2
Bruno's Tavern
Member since Apr 2015
1933 posts
Posted on 3/15/18 at 9:29 am to
Maybe his DNA is different because the aliens took him and sent back someone different
Posted by iAmBatman
The Batcave
Member since Mar 2011
12382 posts
Posted on 3/15/18 at 9:40 am to
Astronauts were from Germany
This post was edited on 3/15/18 at 9:41 am
Posted by Bard
Definitely NOT an admin
Member since Oct 2008
51679 posts
Posted on 3/15/18 at 9:43 am to
I've heard of a few people that have had that happen to them...

Posted by Flashback
reading the chicken bones
Member since Apr 2008
8315 posts
Posted on 3/15/18 at 10:14 am to
quote:


Scott’s telomeres (endcaps of chromosomes that shorten as one ages) actually became significantly longer in space.


Thats what she said
Posted by Upperdecker
St. George, LA
Member since Nov 2014
30584 posts
Posted on 3/15/18 at 10:22 am to
Shorter telomeres can lead to more risk of disease. Someone needs to do a study on astronauts and disease. If they have longer telomeres they should have a reduced risk
Posted by SpeckledTiger
Denham Springs
Member since Jul 2010
1477 posts
Posted on 3/15/18 at 11:01 am to
Interstellar was a market tester of research results to see if the public would accept that Matt Damon would out live us all.
Posted by Fezzik
Gilder
Member since Oct 2017
61 posts
Posted on 3/15/18 at 11:11 am to
So what does this say?

Will he live to be 150? Does his wang double in size? Is he bulletproof?

Posted by TheCaterpillar
Member since Jan 2004
76774 posts
Posted on 3/15/18 at 11:12 am to
This is some cool shite.
Posted by Sneaky__Sally
Member since Jul 2015
12364 posts
Posted on 3/15/18 at 11:15 am to
Would be incredible to look back on generational changes if they actually develop an outpost on Mars.
Posted by Volvagia
Fort Worth
Member since Mar 2006
51910 posts
Posted on 3/15/18 at 11:31 am to
Hey, you folks who bitch about NASA being a waste.

This kind of shite is why it’s good.

You keep pushing boundaries and breaking new ground, you never know what you’ll discover.

Now they can start an investigation into why.

Is it the micro gravity? Is it the low grade impact of radiation? If so, what type is ideal? Can the effect be recreated on earth?
Posted by el Gaucho
He/They
Member since Dec 2010
53019 posts
Posted on 3/15/18 at 11:36 am to
Space isn't real
Posted by Langland
Trumplandia
Member since Apr 2014
15382 posts
Posted on 3/15/18 at 11:47 am to
quote:

93% of Scott’s genes returned to normal after landing


So does this mean that Scott is now a banana?
Posted by GetEmTigers08
Mississippi
Member since Dec 2007
1236 posts
Posted on 3/15/18 at 12:33 pm to
I think the lack of gravity must have some effect on DNA, down to the molecular level. A good analogy for the DNA lengthening would be how a person gets a bit taller in space because of less pressure being put on spine, allowing it to lengthen back out. I would be interested to see how much effect is from gravity and how much is from more radiation exposure in space(will be really bad going to mars or elsewhere)
Posted by Bard
Definitely NOT an admin
Member since Oct 2008
51679 posts
Posted on 3/15/18 at 12:38 pm to
quote:

Scott’s telomeres (endcaps of chromosomes that shorten as one ages) actually became significantly longer in space. While this finding was presented in 2017, the team verified this unexpected change with multiple assays and genomics testing. Additionally, a new finding is that the majority of those telomeres shortened within two days of Scott’s return to Earth.


This is especially interesting as one of the theories gaining traction is that telomeres are a primary driver in the aging process (each time a cell copies itself, the telomeres shorten).
Posted by dkreller
Laffy
Member since Jan 2009
30328 posts
Posted on 3/15/18 at 12:38 pm to
quote:

Long-Term Space Exposure Alters DNA


Well no shite.

It might have something to do with all of that radiation exposure.
Posted by lsu13lsu
Member since Jan 2008
11484 posts
Posted on 3/15/18 at 1:18 pm to
quote:

Hey, you folks who bitch about NASA being a waste.


I rarely hear people bitching about NASA being a waste. Most bitch about big government spending on welfare and world police instead of this. Also, NASA doesn't help themselves by getting involved in muslim outreach.
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