re: FDA Grants Full Approval for Vaccine

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yea that was embarrassing

all the outdoor gym equipment and tennis courts were roped off and basketball hoops were taken down in new Orleans lol

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And the sad part was despite the facts....people blamed gyms for spreading it.

Fat people on both sides will do anything to excuse their behavior

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The flu sucks for a few days too but no one is freaking out over mass vaxxing for it or cares if people get the flu shot or not.

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Because at this point we can’t eradicate the flu.

There was some hope that we could eradicate COVID-19 through high vaccination numbers but that’s likely not to happen as long as the virus has viable hosts to mutate and vaccination rates stay on the lower end compared to something like polio.

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like I'm healthy as shite and COVID fricking sucked and made me miserable for 10 days

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So you had the flu.

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Because at this point we can’t eradicate the flu.

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Says the terrorist who won’t stay home and save lives

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But there wasn't any flu last year

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I credit that to the large number of kids who were virtual during typical flu season and people actually staying home from work sick. And people upping their hygiene regimes.

We also saw far less mono in schools as well.

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So you had the flu.

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The flu has respiratory side effects still manifesting itself months later?

Never knew that

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The flu has respiratory side effects still manifesting itself months later?

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It actually does but I don’t get your point.

To speak to the question about efficacy. The vaccine and immunity for that matter is not an all or none proposition. It is a numbers game - its the number of viral particle circulating vs the number of neutralizing antibodies circulating. With this variant and the number of people infected, the number of circulating viral copies in an individual and in the community at large is overwhelming. Immunity is not simply a binary situation, but rather a sliding scale. MMR is a good example of a vaccine that in some produces very long-lasting immunity, where in others functional immunity is of a much shorter duration. Because of how long the vaccine has been around "immunity" can be quantified with antibody titers (with respect to Rubeola and Rubella at least, with mumps it is not so clear).

It may be that one single booster increases antibodies to a high enough level to do the trick and even prevent mild to moderate disease in almost everyone and for a long time, or it may be that boosters are needed periodically - there is truly no way to know that at this stage of the game, but the vaccine(s) are unquestionably beneficial at this time. And I'm not so sure why so many people would be so bent out of shape for periodic boosters when many vaccines require such already.

The gold mine is going to be something that stimulates a neutralizing mucosal antibody (IgA) that can be produced in high enough quantities at the points of entry for the virus (particularly the nasopharynx). For now best way to overcome this is to have as many folks with some immunity (yes that includes persons with past infection) as possible versus persons that are immunologically naïve to this virus.