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Posted on 3/17/20 at 6:16 pm to S1C EM
Not unless you were in an at risk group with a known probable exposure, no
Posted on 3/17/20 at 6:20 pm to Stevo
quote:
for someone who is not an MD, you know a ton of science.
In between running a tight ship at my Burger King, and having a stash of Impossible Whoppers put aside prior to the hoarding rush, I have a lot of time to read Wikipedia. Owner’s okay with it as long as I don’t burn the fries again.
Posted on 3/17/20 at 6:24 pm to Volvagia
quote:
Impossible Whoppers
This will never get old
I was surprised to see them testing people at the urgent care I was at today. Apparently I was lucky enough to share a waiting room with their first person they were testing.
Posted on 3/17/20 at 6:26 pm to BallsEleven
See this right here. Do we need to test to treat or to satisfy our morbid curiosity. Did that pts desire to be tested put more people at risk? Could that pt have stayed home and taken care of themselves? If you aren’t sick enough to need around the clock care maybe pts should stay home...
Posted on 3/17/20 at 6:28 pm to More beer please
quote:
Looks like the number of new cases each day isn’t increasing exponentially.
Posted on 3/17/20 at 6:30 pm to BallsEleven
quote:
This will never get old
And I think it really chaps the arse of someone that I turned the weak insult to a joke.
I seem to often gain a serial DVer after mocking it.
Posted on 3/17/20 at 6:31 pm to MrSmith
Oh goody, more Excel analysis.
Posted on 3/17/20 at 6:32 pm to Volvagia
Development of coronavirus treatment advancing in Japan with existing meds
Promising news from Japan
quote:
One medicine that experts in a government panel have expressed hope in is Ciclesonide (marketed as Alvesco), a type of steroid used in inhalers to treat asthma. A medical team including members of the Kanagawa Prefectural Ashigarakami Hospital administered this drug to three coronavirus disease patients. One of them, a woman in her 70s, saw her fever go down after two days, and her pneumonia symptoms also improved. She later tested negative for the virus and was discharged from hospital after eight days. The other two patients, a man in his 70s and a woman in her 60s, were able to be taken off respirators after receiving the medicine. Currently around 10 people are receiving it.
quote:
Also being tested is Remdesivir, which was developed as a treatment for the Ebola virus disease. As of March 16, it had been administered to nine patients. Japan's National Center for Global Health and Medicine is participating in international joint clinical trials with the United States and other countries to test the effectiveness of this medicine. Center official Norio Omagari said it had only been used in serious cases in which patients were on artificial respirators or heart-lung machines, but none of them had died.
quote:
Hydroxychloroquine (Plaquenil), which was developed to treat malaria, is a similar sort of medicine. When it was given to a male coronavirus disease patient in his 60s who was receiving dialysis treatment due to diabetes, his fever of over 38 degrees Celsius went down after three days, and his symptoms of pneumonia also improved. It is expected he can be released from hospital if he tests negative for the virus.
quote:
One more drug in focus is Favipiravir (Avigan), which is used to treat new types of influenza. Japan has a stockpile of about 2 million Avigan pills. Clinical research using the medication on novel coronavirus disease patients with mild to moderate symptoms began in March. The HIV treatment drug Lopinavir/ritonavir (Kaletra) is also being tested, having been administered to 54 patients as of March 1. It is hoped that both of these medications will be effective in preventing the virus from multiplying in patients' bodies. However, an individual related to Japan's Ministry of Health Labor and Welfare pointed out, "We've given Avigan to 70 to 80 people, but it doesn't seem to work that well when the virus has already multiplied. The same goes for Kaletra." Furthermore, care is said to be needed when women who could be pregnant or men who are trying to have children with their partners use Avigan, as it can subsequently cause deformities in fetuses.
Promising news from Japan
Posted on 3/17/20 at 6:39 pm to Volvagia
I don’t think you know what analysis means
Posted on 3/17/20 at 6:39 pm to MrSmith
quote:
@AllisonFox4News
Nine new cases in Dallas County: two in their 20s, one in 30s, two in 40s, two in 50s, one in 60s, one in 70s. Eight are in city of Dallas. One case related to international travel. Three related to close contacts with COVID-19. Five are likely community spread.
quote:
@AllisonFox4News
Just received confirmation on this from Dallas @JudgeClayJ chief of staff -- patients who have coronavirus and are in their 20s and 30s being treated now at Dallas hospitals are in critical condition and have no underlying conditions.
Posted on 3/17/20 at 6:40 pm to jennBN
quote:
See this right here. Do we need to test to treat or to satisfy our morbid curiosity. Did that pts desire to be tested put more people at risk? Could that pt have stayed home and taken care of themselves? If you aren’t sick enough to need around the clock care maybe pts should stay home...
It was an older patient who had recently traveled and was coughing a decent bit so I would think it would be best to know for sure if they had it. As soon as the staff realized they had came back from a trip, they made them wait in their car and swabbed them out there.
Posted on 3/17/20 at 6:43 pm to tigerskin
quote:
Extensive drive through testing is the answer
So why aren't we all being tested? And also, if I go and get tested and I'm negative, who's to say I won't come into contact with someone positive but doesn't know it if THEY haven't been tested because they chose not to? My mind is fried.
It seems that some say this is the answer and others not so much.
This post was edited on 3/17/20 at 6:45 pm
Posted on 3/17/20 at 6:45 pm to GEAUXmedic
quote:
@AllisonFox4News
Just received confirmation on this from Dallas @JudgeClayJ chief of staff -- patients who have coronavirus and are in their 20s and 30s being treated now at Dallas hospitals are in critical condition and have no underlying conditions.
These are the reports I don't get. That's not really consistent with any reports so far, so what's the difference with these? And what is the requirement to be considered critical? Intubated?
Posted on 3/17/20 at 6:47 pm to Ingeniero
update on the patient we are treating with hydroxychloroquine:
their temperature broke almost immediately after the 2nd dose.
after day 2 of therapy hopefully we will start to see some improvement on imaging/oxygenation
their temperature broke almost immediately after the 2nd dose.
after day 2 of therapy hopefully we will start to see some improvement on imaging/oxygenation
This post was edited on 3/18/20 at 8:22 am
Posted on 3/17/20 at 6:47 pm to Ingeniero
quote:
These are the reports I don't get. That's not really consistent with any reports so far, so what's the difference with these? And what is the requirement to be considered critical? Intubated?
That’s why I don’t trust anything on twitter. And you are right we don’t have any details. Are they intubated or being watched closely. Big difference. No one is saying young people can’t get very sick, they can but I think we have enough data now to say this isn’t the norm.
Posted on 3/17/20 at 6:48 pm to uscpuke
quote:
5000 people have tested positive. 1/4 happen to be celebrities. WTF
One more data point that says this is probably about ten times more prevalent than the number of known cases. In some ways that might be a good thing and show that we are overreaching in our response.
Posted on 3/17/20 at 6:49 pm to Tiguar
quote:
update on the patient we are treating with hydroxychloroquine: his temperature broke almost immediately after the 2nd dose. today is day 2 of therapy, so hopefully we will start to see some improvement on imaging/oxygenation tomorrow.
Great news Tiguar! Keep us updated. Are y’all doing 600mg daily? As one dose or divided up?
Posted on 3/17/20 at 6:50 pm to WaWaWeeWa
we are not.
that is the dose studied to get the necessary levels, but its above the daily max dose
we did 400mg x2 on day 1 (800mg for the day) then 200mg BID after (400/day)
the half-life should allow that to stay therapeutic for the duration of therapy with that loading dose
that is the dose studied to get the necessary levels, but its above the daily max dose
we did 400mg x2 on day 1 (800mg for the day) then 200mg BID after (400/day)
the half-life should allow that to stay therapeutic for the duration of therapy with that loading dose
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