Posted by
Message
lsupride87
LSU Fan
Member since Dec 2007
66369 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
quote:

At this point I don’t think we can exclude the possibility that the antibody tests have dramatically Underestimated the number of infections.

My doctor is convinced I fall in this category

I lost all my taste and had a sore throat 3 weeks ago. I didnt get tested, because there is ZERO reason to. Instead, I stayed home until symptoms were gone

Antibody test showed negative this week


Penrod
LSU Fan
Member since Jan 2011
15945 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
quote:

At this point I don’t think we can exclude the possibility that the antibody tests have dramatically Underestimated the number of infections.

we could actually be nearing herd immunity and the studies of T cells being present in 70% of patients could be an indicator of that. Once antibodies fall below detectable levels the only evidence of previous infection would be T cells.

There is no question that antibody tests are underestimating. I think all American epidemiologists should have their eyes glued to Jefferson and Orleans Parishes. These are the first areas in America undergoing a second wave. We’ve been “open” for two and a half months, and so far, not much. More days of data are necessary, but it looks promising.


WaWaWeeWa
Member since Oct 2015
8431 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
quote:

I lost all my taste and had a sore throat 3 weeks ago. I didnt get tested, because there is ZERO reason to. Instead, I stayed home until symptoms were gone Antibody test showed negative this week


It probably hasn’t been long enough. Studies showed that mild/asymptomatic infections can take much longer to reach the antibody levels needed to test positive.

I would repeat that antibody test in 6-8 weeks


GoCrazyAuburn
Auburn Fan
Member since Feb 2010
29612 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
Even with that in mind, I think it can be pretty safely assumed even the antibody tests are grossly underestimating the total infected. Wasn’t the CDC saying that totals could be ranging anywhere from 30% to 75% higher, but using the 30%. I think it is much closer to the 75%


Replies (0)
Replies (0)
01
Sasquatch Smash
LSU Fan
Member since Nov 2007
11208 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
Seroprevalence preprint out of Kenya.

They definitely should look into what's going on in Africa. Very small death toll there, despite having antibody percentages similar to other places; estimating ~5% for the country with only 71 deaths at the time of study.

I'm sure there are lots of factors at play for this, but I'm sure having a younger population has helped. HCQ being over the counter there?
This post was edited on 7/31 at 1:15 pm


CrownTownHalo
Mississippi St. Fan
CrownTown, NC
Member since Sep 2011
808 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
So my kids physician discouraged an antibody test. He said that it would pick up other Coronavirus antibodies that weren’t necessarily SARS COV V2. So a common cold type thing could show a positive.

Was he full,of,shit?
This post was edited on 7/31 at 2:12 pm


Sasquatch Smash
LSU Fan
Member since Nov 2007
11208 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
quote:

Was he full,of,shit?


I don't know. Did you ask him about his bowel movements?




But, no, not entirely. There are potential issues when it comes to specificity and sensitivity with the tests.


ell_13
Member since Apr 2013
66591 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
quote:

Can you describe your symptoms in March?
No fever. It was about a week of coughing. Not a nasal drip but a deep cough in my chest that almost hurt. Even the week after it was difficult to take a deep breath without some pain. Fatigue for sure. That lasted the full two weeks. At the time I had to be negative for flu before they would give me the covid one and even then they were reluctant because of my age and health. My PCD basically told me to quarantine for 2 weeks whether I could get a test or not. Was able to get one through my wife’s work (Ochsner).


Scrimpin Gary
Auburn Fan
ATX
Member since Feb 2013
617 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
I’m curious if I fall into this category. Fever, dry cough, lethargy and chest tightness (difficult walking up the stairs without being out of breath). Called the doctor but was told they couldn’t test me as I’m under 40 and all tests were being used on 50+ with fever. This was early March after my kids daycare teacher was in the hospital for an unknown respiratory virus (later the daycare shut down for cleaning due to Covid positives). The whole family got this. Took an antibody rest last week and it was negative. Whatever we had in early March matched Covid and I’ve had nothing like it. It was also what I’d consider mild.


Boo Krewe
Member since Apr 2015
6829 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
Tightness in chest . Feel like I'm tasting blood. I hope no long lasting damage. I want to cry. Body aches


TD SponsorTD Fan
USA
Member since 2001
Thank you for supporting our sponsors
Advertisement
Bullfrog
LSU Fan
but I left before halftime.
Member since Jul 2010
46820 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
Did you die yet?


buckeye_vol
Ohio State Fan
Member since Jul 2014
33380 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
quote:

But, no, not entirely. There are potential issues when it comes to specificity and sensitivity with the tests.
I’m curious. Would the antibody tests naturally get more accurate as we move further from cold/flu season when people were more likely to have recently had something that would cause cross-reactivity?

Obviously they should be more accurate as the base rates get to a reasonable level, of especially on the backside of a local outbreak. Plus hopefully the tests, sampling methodology, and analyses improve too.


WaWaWeeWa
Member since Oct 2015
8431 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
quote:

move further from cold/flu season when people were more likely to have recently had something that would cause cross-reactivity?


When you say “accurate” it comes off as sounding like you think they are currently inflated.

I would be less concerned about cross reactivity and more concerned about the tests inability to detect patients with mild or asymptomatic cases months ago.

I’m not confident the antibody tests we have can detect an asymptomatic case 6 months ago in February, yet we know they occurred.

I think antibody studies are actually going to show declining rates going forward and it has nothing to do with cross reactivity.

We may have to focus on more specific T cell tests in smaller samples
This post was edited on 8/1 at 9:15 am


Boo Krewe
Member since Apr 2015
6829 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
Do you want me too ? Need a snack and sleep


Bullfrog
LSU Fan
but I left before halftime.
Member since Jul 2010
46820 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
Not necessarily.
Just checking to see if the sorority girls can relax yet.


buckeye_vol
Ohio State Fan
Member since Jul 2014
33380 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
quote:

When you say “accurate” it comes off as sounding like you think they are currently inflated.
I was referring to the post from earlier that said
quote:

He said that it would pick up other Coronavirus antibodies that weren’t necessarily SARS COV V2. So a common cold type thing could show a positive.
But I do think they were inflated in the early studies, but the risk of undercounting would probably be greater later on, although the magnitude of the proportional error is less even if the absolute error is greater. In other words, +/- 2% around an estimate of 3% is worse than +/- 5% around an estimate of 25%, despite a larger absolute interval.


Replies (0)
Replies (0)
00
Boo Krewe
Member since Apr 2015
6829 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
Ive stopped.caring
Lost any sense of arousal


philly444
LSU Fan
stuck in contraflow
Member since Nov 2008
8222 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
No one should ever die a virgin


BRIllini07
Chicago Cubs Fan
Baton Rouge, LA
Member since Feb 2015
1794 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
In this week’s edition of “JBE and the Dems aren’t over reacting, most of humanity is”

Ireland debating reopening pubs, and the decision has been pushed back:

LINK

Ireland, with 26,000 cases total has been averaging less than 25 cases per day since late May. Overall population 50% higher than Louisiana.


Replies (0)
Replies (0)
00
Boo Krewe
Member since Apr 2015
6829 posts

re: Coronavirus Disease 2019 (COVID-19) ***W.H.O. DECLARES A GLOBAL PANDEMIC***
Might happen for me. Chest is tight, hurts to move. Wish I could go for walk


Replies (0)
Replies (0)
00
first pageprev pagePage 1168 of 1170next pagelast page

Back to top

logoFollow TigerDroppings for LSU Football News
Follow us on Twitter, Facebook and Instagram to get the latest updates on LSU Football and Recruiting.

FacebookTwitterInstagram