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re: Need Info on TRT

Posted on 4/3/25 at 1:32 pm to
Posted by Uncle JackD
Member since Nov 2007
59436 posts
Posted on 4/3/25 at 1:32 pm to
Estradiol, Sensitive (LC/MS-MS)
Posted by Arkapigdiesel
Faulkner County
Member since Jun 2009
15427 posts
Posted on 4/10/25 at 8:03 pm to
This thread has been a treasure trove of info.

I'm starting TRT next week. Doc prescribed test cypionate that I'll be injecting every other day at .2 per injection. My free test was at 44.8 pg/mL and bioavailable was at 94.2 ng/dL.

Been tired and overall lethargic for a long time now. Also wake up a lot throughout the night. Despite all of that, I still workout hard and have been doing CrossFit for about a year and half now.

I'm more concerned with getting my energy level up and sleeping better. If I put up some lean muscle, then so be it.

Per lsu777's advice, I ordered some luer lock 1 cc syringes, 20 gauge 1" luer lock draw needles and some 29 gauge 1/2" luer lock needles for the sub-q injections.

I'm ready to see what I'll feel like doing the TRT.
Posted by SaDaTayMoses
Member since Oct 2005
4543 posts
Posted on 4/12/25 at 9:02 am to
Anyone ever try Jatenzo 237mg? It's in capsule form taken twice daily. I started this about 2 weeks ago...seems to make me heavier but not fatter or a bigger gut. I am lifting weights 5 days a week but nothing super crazy. I think I've gained about 8-9 lbs in 2 weeks, but like I said, it's not in my gut area.
I have not run any more blood tests yet.
Posted by lsucoonass
shreveport and east texas
Member since Nov 2003
69709 posts
Posted on 4/17/25 at 4:10 pm to
Just got my lab results back

In one year I went from total testosterone 240 to 909
Free test 7.8 to 31.2
SHBG 9, this has fluctuated from 11-9
Estradiol at 64, was in the 30’s or lower within my first 3 months of use

Would it be time to consider an AI? I’m not feeling any effects indicative of my high estradiol. J feel very close to optimal. Over this one year I went from injecting test cypionate 125 mg/ml once a week to now 220 mg/ml once weekly
This post was edited on 4/17/25 at 4:52 pm
Posted by Carson123987
Middle Court at the Rec
Member since Jul 2011
67797 posts
Posted on 4/17/25 at 5:11 pm to
quote:

I'll be injecting every other day at .2 per injection.


That's gonna get really old really fast. Just inject Mon/Thurs like everyone else. Go plot it out on steroidplotter - there is no substantive difference in level swings and it will be much more inconvenient



quote:

1 cc syringes, 20 gauge 1" luer lock draw needles


Pay attention for coring (little bits of rubber falling in the test) from the vial's stopper, it's generally advised to stick with 22ga to avoid it. I've had it happen with 18ga and 20ga in pharma test vials

I personally use 22ga to draw, 27ga 1/2" to inject in abdomen
Posted by Carson123987
Middle Court at the Rec
Member since Jul 2011
67797 posts
Posted on 4/17/25 at 5:12 pm to
quote:

Estradiol at 64, was in the 30’s or lower within my first 3 months of use

Would it be time to consider an AI?


Yes, you want to stay around 30. I don't take AI regularly and only use it when I feel symptomatic. Over time you will learn to feel when it's running high
Posted by Carson123987
Middle Court at the Rec
Member since Jul 2011
67797 posts
Posted on 4/17/25 at 5:14 pm to
quote:


Has anyone ever tried Clomid?


Any doctor that recommends clomid monotherapy for testosterone deficiency is retarded and should be ridiculed. Post his name here so we can roast him
Posted by TigerFanatic99
South Bend, Indiana
Member since Jan 2007
34727 posts
Posted on 4/20/25 at 10:56 am to
quote:

Any doctor that recommends clomid monotherapy for testosterone deficiency is retarded and should be ridiculed. Post his name here so we can roast him


Closed I agree. I would like to see enclomiphene citrate looked at a little more seriously though.
Posted by Carson123987
Middle Court at the Rec
Member since Jul 2011
67797 posts
Posted on 4/20/25 at 11:41 am to
quote:

would like to see enclomiphene citrate looked at a little more seriously though.


I was very hopeful that removing zuclomiphene from the equation would be a breakthrough, but sadly the majority of feedback I’ve seen from enclomiphene users is similar to clomid
Posted by Arkapigdiesel
Faulkner County
Member since Jun 2009
15427 posts
Posted on 4/24/25 at 8:32 pm to
My test cypionate finally came in today. Gave myself my first .2 sub q injection. Looking forward to getting to peak levels. According to the chart I did below, I'll get to near peak levels around Week 3 at an every other day injection.

Posted by GeekedUp
Virginia
Member since Jun 2009
3064 posts
Posted on 4/27/25 at 8:57 am to
quote:

start at about 150mg total per week split into 2 shots



Was about 250 and started at only 100mg/week split into two does. Seems to be helping but I do get mild acne on my upper back. Really frustrating given it’s such a low does
Posted by AFtigerFan
Louisiana
Member since Feb 2008
3673 posts
Posted on 4/27/25 at 9:31 am to
quote:

Was about 250
Is 250 a week a low dose? That seems to be at least double what most protocols listed on here are. Mine is 100 every 5 days and it’s worked wonders for me.

ETA - or was 250 your testosterone level before you started? I haven’t had any acne issues with the 100mg every 5 days.
This post was edited on 4/27/25 at 3:34 pm
Posted by GeekedUp
Virginia
Member since Jun 2009
3064 posts
Posted on 4/28/25 at 3:38 pm to
quote:

or was 250 your testosterone level before you started?


This.

Yeah man it’s odd. Didn’t have especially bad acne when I was young either.

I did gel TRT back in the day without issue. A bit of pain but no sides.

Fast forward and my PCP recommended 200mg (1ml)once every 2 weeks. I did that a couple times before realizing how stupid it was.

Now I do 50mg (.25ml) twice per week. I inject what I think is subcue, basically below the belly button and an inch or two the left/right.

Recently started washing with salicylic acid and a long handle brush to reach my back. We will see if that helps.

Posted by beaux duke
Member since Oct 2023
3296 posts
Posted on 4/28/25 at 9:26 pm to
if i wanted to get a summary of this thread but didn't want to read 28 pages, what should i know?
thanks in advance, big ask for sure
eta - took sarms for a couple years but not in the past year. noticeable difference. rad 140 and gw501516. not to get huge. 50 yr old trail runner trying to get slightly faster
thanks again
This post was edited on 4/28/25 at 9:29 pm
Posted by Fachie
Magnolia
Member since Mar 2017
526 posts
Posted on 4/29/25 at 9:37 am to
quote:

didn't want to read 28 pages


Reading is educating yourself. If you don't want to do that then TRT isn't the thing for you. Success with it comes more from YOU educating yourself, and understanding, than a Dr writing you a script. Easier to find an uneducated Dr than it is to find a good one, no sense in 2 dummies playing with your hormones.

That's the summary you need.
Posted by meeple
Carcassonne
Member since May 2011
10844 posts
Posted on 5/5/25 at 12:13 pm to
I’m able to get a 10 mL vial. I’m doing IM injections. Is heating and reheating this up over the course of 4 months (16 injections, once per week) ok as far as it staying good?

Or, is heating it up necessary if going the IM route, and if not what needle size should be used to draw and inject?
Posted by TigerFanatic99
South Bend, Indiana
Member since Jan 2007
34727 posts
Posted on 5/5/25 at 2:30 pm to
quote:

if i wanted to get a summary of this thread but didn't want to read 28 pages, what should i know?
thanks in advance, big ask for sure


You'll get the standard "You're too stupid to do TRT if you can't even read five hundred and fifty posts and put it all together!!!@12!!!" responses here.

Just give the link to page 1 to Grok, tell it this is a twenty-something page thread you need summarized, making particular note of information that people reacted appreciatively to or otherwise actively discussed.
Posted by lsu777
Lake Charles
Member since Jan 2004
36771 posts
Posted on 5/5/25 at 2:38 pm to
quote:


if i wanted to get a summary of this thread but didn't want to read 28 pages, what should i know?
thanks in advance, big ask for sure
eta - took sarms for a couple years but not in the past year. noticeable difference. rad 140 and gw501516. not to get huge. 50 yr old trail runner trying to get slightly faster
thanks again


1) get your levels tested (total test, free test, shgb, estrodial, igf)

2) if total test is low and you have symptoms of low test look to start at 150mg a week. Start with 1 shot per week in the belly fat(subq)

3) if free test is low and you no longer get morning wood, add 12-15mg of boron in the morning.

2 & 3 can both happen or just one or the other. i always suggest boron no matter what.

pretty much it in a nut shell

everyone should be taking minimum of 5mg Cialis daily for blood flow.


pretty much your summary. if you have specific questions fire away.
Posted by lsu777
Lake Charles
Member since Jan 2004
36771 posts
Posted on 5/5/25 at 2:39 pm to
quote:

You'll get the standard "You're too stupid to do TRT if you can't even read five hundred and fifty posts and put it all together!!!@12!!!" responses here.

Just give the link to page 1 to Grok, tell it this is a twenty-something page thread you need summarized, making particular note of information that people reacted appreciatively to or otherwise actively discussed.


i mean i wouldnt say that but if you are going to do a life long decision its prolly best to do at least a couple hours of research
Posted by Marciano1
Marksville, LA
Member since Jun 2009
19795 posts
Posted on 5/5/25 at 3:39 pm to
Not on TRT or any supplements but starting to get the low energy/libido thing. I just seem to be 'not in the mood' to do anything these days that I used to enjoy. I'll be 38 this month. Think I'll get my levels checked in the next few weeks.
This post was edited on 5/5/25 at 3:42 pm
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