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A good analogy for cholesterol?

Posted on 1/30/25 at 8:02 am
Posted by scottydoesntknow
Member since Nov 2023
7282 posts
Posted on 1/30/25 at 8:02 am
The majority of the public really has no idea what the purposes of cholesterol is and what its mechanism for contributing to heart disease. I think this analogy explains it well but let me know...

The body is like a construction site with pathways(circulatory system) for carts(cholesterol) that are constantly carrying rocks around(fats). When the pathways are smooth, everything goes fine, no matter how many carts are on the road. When the path is bumpy(inflammation) the carts will lose some of their rocks on the road and they will accumulate on the bumpy parts of the road, making the road even more bumpy and accumulating even more rocks.

Statins only lower cholesterol which is basically just reducing the number of carts on the road which can hit the bumpy spots and lose rocks. The problem is that the body naturally produces the amount of cholesterol it needs irrespective of the pathways. If you artificially lower cholesterol, you are inhibiting the body from working optimally.

For the entirety of the time the medical community has known about heart disease(really only ~100 years, theyve only been obsessed with lowering the # of carts on the pathways....not reducing the prevalence of bumpy spots on the pathways. We are only reducing the symptoms...not addressing the source of the problem
This post was edited on 1/30/25 at 8:04 am
Posted by Aubie Spr96
lolwut?
Member since Dec 2009
43183 posts
Posted on 1/30/25 at 8:48 am to
quote:

We are only reducing the symptoms...not addressing the source of the problem



This has been modern medicine for the last 200 yrs.
Posted by BankLSU
You cant be any geek off the street
Member since Nov 2005
761 posts
Posted on 1/30/25 at 10:29 am to
Ok, then how do you get rid of the bumpy roads?
Posted by OysterPoBoy
City of St. George
Member since Jul 2013
40418 posts
Posted on 1/30/25 at 11:15 am to
Probably stop eating sugar and high processed foods.
Posted by scottydoesntknow
Member since Nov 2023
7282 posts
Posted on 1/30/25 at 11:28 am to
quote:

Ok, then how do you get rid of the bumpy roads?


That is the logical question. The answer seems to be to abstain from things that cause inflammation. This is the path I wish research would go down
Posted by chryso
Baton Rouge
Member since Jul 2008
13055 posts
Posted on 1/30/25 at 3:30 pm to
quote:

The answer seems to be to abstain from things that cause inflammation. This is the path I wish research would go down


Unfortunately, that isn't where they make money.
Posted by scottydoesntknow
Member since Nov 2023
7282 posts
Posted on 1/30/25 at 5:06 pm to
quote:

Unfortunately, that isn't where they make money.


Unfortunately
Posted by Cali 4 LSU
GEAUX TIGERS!
Member since Sep 2007
6658 posts
Posted on 1/30/25 at 11:57 pm to
Great analogy.

I always tell people that when you eat:
-processed foods (as they oxidize easily)
-inflammatory foods
-foods that increase blood sugar levels
especially in the presence of high blood pressure, nics & scraps occur on the inside of arteries. As a result of these injuries, the body uses it's natural repair system (cholesterol) to "spackle" that area of vessel. In construction we sand down the spackle once it dries but if that doesn't happen in the vessels, it closes in the lumen. If we have less LDL (bad cholesterol) then there is less chance of a "bad" spackle job.

But yea...inflammation is the underlying culprit that our body is reacting to considering all cells in our body are made of cholesterol. So there is an immune component to all of this (think foam cells, etc).

There is nothing wrong with achieving healthy cholesterol levels but the inflammation should not be ignored.
Posted by rebelrouser
Columbia, SC
Member since Feb 2013
12070 posts
Posted on 1/31/25 at 8:07 am to
Thanks. I've always wondered about this issue. My doc has me on statins but i exercise regularly and eat NOVA 1. I wonder if i really need them. I will bring it up again during my next check up.
Posted by Reubaltaich
A nation under duress
Member since Jun 2006
5183 posts
Posted on 1/31/25 at 12:52 pm to
That's a fair analogy of how cholesterol clogs up arteries but its not 100% correct.

For many decades MDs and more specially, cardiologist were taught the 'plumbing model' of CL and the arteries. Much like a kitchen sink that gets clogged up with grease.

Medical research in the last 25 years has revealed that the LDL Cholesterol molecule , when it becomes oxidized, will burrow into the artery cell walls, causing blockage.

Most folks don't realize that our bodies produce cholesterol, mostly in the liver. Our bodies could not function without cholesterol.

Most lipid test just focuses on LDLs, HDLs, and Triglycerides.
Request advanced lipid testing.
Many people who were deemed healthy as a horse whose cholesterol seemed great either had a heart attack or stroke.

Medical reseach is starting to reveal more and more markers to heart disease:

A doc advised me to get these checked as well:
Get an ankle-brachial index test to look for PAD(peripheral artery disease ).
Its a very simple test that takes just a few minutes.

Get or request advanced lipid testing.
Most standard lipid test just focus on triglycerides, LDLs & HDLs.
Medical research is revealing other markers that can lead to coronary diseases, heart attacks and strokes.
The 'widow maker' heart attack has been linked to LipoA(Lipoprotein A) that is a must to checked.
Also ApoB(Apolipoproten B) needs to be checked.





This a good sight to read about cholesterol: LINK

BTW, I am not a medical professional.
Posted by Big Scrub TX
Member since Dec 2013
36803 posts
Posted on 1/31/25 at 1:23 pm to
quote:

The 'widow maker' heart attack has been linked to LipoA(Lipoprotein A) that is a must to checked.
Also ApoB(Apolipoproten B) needs to be checked.
Posted by scottydoesntknow
Member since Nov 2023
7282 posts
Posted on 1/31/25 at 5:59 pm to
quote:


Thanks. I've always wondered about this issue. My doc has me on statins but i exercise regularly and eat NOVA 1. I wonder if i really need them. I will bring it up again during my next check up.


I got my dad off statins. He has high cholesterol, but he doesnt have high blood pressure at all. He told his doc no thanks.
Posted by TigerBait1980
New Orleans
Member since Jul 2009
414 posts
Posted on 2/1/25 at 10:32 am to
Going to get a Calcium CT of the heart to look for calcium deposit build up. This is what my doctor ordered as he said cholesterol is only one factor. If deposits are present, I will get on statins. Crazy part is the tests only cost $100 but are not covered by insurance. Would make sense that people regularly got this scam done.
Posted by novabill
Crossville, TN
Member since Sep 2005
10648 posts
Posted on 2/1/25 at 10:54 am to
Timely thread

Just had 2 stents yesterday.

Time to get more educated as all they wanted to talk about was statins and blood thinners
Posted by LemmyLives
Texas
Member since Mar 2019
9995 posts
Posted on 2/1/25 at 2:37 pm to
quote:

processed foods


Can you people start defining what this actually means? The deer sausage in my fridge is processed, and so are oats that got worked over and rolled. You’re inflaming stupid women with hubbys paycheck to blow.
Posted by scottydoesntknow
Member since Nov 2023
7282 posts
Posted on 2/1/25 at 3:38 pm to
quote:

Can you people start defining what this actually means?


Fair question. Id say a food that must go through many steps to make it into its final edible form and/or shelf stable. They will contain salts, sugars and fats not normally used in an average kitchen(high fructose corn syrup, seed oils, food dyes etc)

Its definitely an arbitrary and overused(im guilty as anyone) term but generally it refers to the shelf stable foods at grocery store(cereal, box dinners, candy, etc)
Posted by Cali 4 LSU
GEAUX TIGERS!
Member since Sep 2007
6658 posts
Posted on 2/1/25 at 4:24 pm to
quote:

Can you people start defining what this actually means?


You're right....technically the really bad stuff is "ultra-processed foods". But what I colloquially mean is:
1.shop the perimeter of the grocery store/avoid center aisles where the "processed" food lives
2. foods with 5 or less ingredients/foods with more than 5 likely have chemicals, stabilizers, emulsifiers, etc
3. foods with 1 ingredient (ie whole foods)/see above
4. avoid added sugar (which is in processed foods): most people walk around with sugar spikes (thus insulin spikes) and never even know it until they have pre-diabetes or diabetes
5. oats=not good for anyone with insulin resistance, especially if they do not contain the whole oat with the outer fiber shell

quote:

You’re inflaming stupid women with hubbys paycheck to blow.


Ah-hem, you are posting to a woman who has, not only hubbys paycheck, but her own to blow. And I'd GLADLY do it for better health. But I don't claim the "inflaming" or "stupid" part of your post.
Posted by Reubaltaich
A nation under duress
Member since Jun 2006
5183 posts
Posted on 2/1/25 at 10:09 pm to
quote:

You're right....technically the really bad stuff is "ultra-processed foods". But what I colloquially mean is: 1.shop the perimeter of the grocery store/avoid center aisles where the "processed" food lives 2. foods with 5 or less ingredients/foods with more than 5 likely have chemicals, stabilizers, emulsifiers, etc 3. foods with 1 ingredient (ie whole foods)/see above 4. avoid added sugar (which is in processed foods): most people walk around with sugar spikes (thus insulin spikes) and never even know it until they have pre-diabetes or diabetes 5. oats=not good for anyone with insulin resistance, especially if they do not contain the whole oat with the outer fiber shell


^^^^Pretty much this^^^^

I know may sound Captain Obvious but just about ALL restaurant food can be listed.
Even all those 'heart healthy' foods they pawn like chicken nuggets.

Anything with hydrogenated or pre-hydrogenated on the label.

Most all store bought breads, even the 'wheat' bread you see on the labels.

Sugar is the HUGE one and is a big stinker.
Big 'food' knows that sugar is highly addicting and add it many of the foods they hawk to keep folks coming back to buy their stuff.
Big 'food' knows that more and more folks are aware of this and they hid it by using many many different names.

By some accounts, there are at least 250 different names for sugar.

Here are just a few commons names that may be found on labels:

1.Agave juice
2.Agave nectar
3.Agave syrup, all varieties
4.Beet sugar
5.Blackstrap molasses
6.Brown rice syrup
7.Brown sugar
8.Buttered syrup
9.Cane juice
10.Cane juice crystals
11.Cane sugar
12.Cane syrup
13.Caramel
14.Carob syrup
15.Castor sugar
16.Coconut sugar
17.Confectioners’ sugar
18.Corn glucose syrup


Many other alias' can be found at this link:
Names for sugar
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