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Tha Alzheimers drug that was a bust may not be a bust after all

Posted on 10/22/19 at 3:04 pm
Posted by Jim Rockford
Member since May 2011
98133 posts
Posted on 10/22/19 at 3:04 pm
LINK

quote:

The drug company Biogen Inc. said Tuesday it will seek federal approval for a medicine to treat early Alzheimer’s disease, a landmark step toward finding a treatment that can alter the course of the most common form of dementia.

The announcement was a surprise because the company earlier this year stopped two studies of the drug when partial results suggested it was not likely to be successful. The company now says a new analysis of more results suggest that the drug helped reduce a decline of thinking skills at the highest dose.

The drug, called aducanumab, aims to help the body clear harmful plaques from the brain. Cambridge, Massachusetts-based Biogen is developing it with a Japanese company, Eisai Co. Ltd.
Posted by TheHarahanian
Actually not Harahan as of 6/2023
Member since May 2017
19495 posts
Posted on 10/22/19 at 3:08 pm to

It works, but they forgot.
Posted by Paluka
One State Over
Member since Dec 2010
10763 posts
Posted on 10/22/19 at 3:16 pm to
Posted by TeddyPadillac
Member since Dec 2010
25446 posts
Posted on 10/22/19 at 3:19 pm to
I think i'd gladly take a drug for early alzheimers even if it had bad side effects, and shortened my life.
I don't think there is a worse disease for an adult.
Posted by deeprig9
Unincorporated Ozora, Georgia
Member since Sep 2012
63867 posts
Posted on 10/22/19 at 3:19 pm to
Put me down for 100.
Posted by ShoeBang
Member since May 2012
19348 posts
Posted on 10/22/19 at 3:21 pm to
quote:

I don't think there is a worse disease for an adult.


I'd rather not know I'm pooping on myself than have anal cancer and know I'm pooping on myself.
Posted by deeprig9
Unincorporated Ozora, Georgia
Member since Sep 2012
63867 posts
Posted on 10/22/19 at 3:25 pm to
The patient isn't suffering so much as their family is, you selfish frick.
Posted by Zappas Stache
Utility Muffin Research Kitchen
Member since Apr 2009
38652 posts
Posted on 10/22/19 at 3:33 pm to
Well, they have a lot of $$$ invested and the FDA is owned by big pharm so why wouldn't they start selling it to desperate people.

Posted by ShoeBang
Member since May 2012
19348 posts
Posted on 10/22/19 at 3:34 pm to
quote:

The patient isn't suffering so much as their family is, you selfish frick.


Yeah, that makes me want it even more knowing it won't hurt. I have a grandma that thinks Joe Burrow is her son and hopes he wins the Heisman. She is happy as frick and she gets to meet new people every day.

Don't tell me about people's family as if that moves the needle, I would much rather see her like this than wasting away from a stroke like my gramps did. Or cancer. Or whatever the frick.

Now who's selfish? What I get from this is you'd rather your family member die in pain so that you don't has the sads when you go visit them because they don't know you. Now thats being a selfish frick right there.
Posted by Malik Agar
Member since Nov 2012
12076 posts
Posted on 10/22/19 at 3:46 pm to
quote:

The patient isn't suffering so much as their family is

Alzheimers patients suffer like crazy. They have no idea wtf is going on and are constantly on edge and terrified. If I ever get it I'm sailing my boat into a hurricane to save me and my family the pain of it.
Posted by Jim Rockford
Member since May 2011
98133 posts
Posted on 10/22/19 at 3:47 pm to
quote:

Alzheimers patients suffer like crazy. They have no idea wtf is going on and are constantly on edge and terrified. If I ever get it I'm sailing my boat into a hurricane to save me and my family the pain of it.


A family friend who's a retired pastor shot himself last year. The consensus was that he must have gotten a diagnosis.
Posted by fishfighter
RIP
Member since Apr 2008
40026 posts
Posted on 10/22/19 at 3:51 pm to
quote:

TheHarahanian


Guess you never had to deal with someone that came down with Alzheimer's.

Cancer sucks, BUT Alzheimer is 10X worse to deal with.

If I had a choice, I would take Cancer 10 fold over.
This post was edited on 10/22/19 at 3:52 pm
Posted by ShoeBang
Member since May 2012
19348 posts
Posted on 10/22/19 at 3:55 pm to
quote:

If I ever get it I'm sailing my boat into a hurricane to save me and my family the pain of it.


I told my wife that if I was able and diagnosed, that I would just go somewhere to die peacefully instead of draining her and the kids to watch it happen.

If I am unable to just go I told her to wait until the first time I don't recognize her and then never come back. Have a service and be done. I'll be dead at that point anyway. When you get the call that my body finally kicked the bucket, have em burn me and bury the ashes.,
Posted by LSUBFA83
Member since May 2012
3320 posts
Posted on 10/22/19 at 5:25 pm to
I know someone who was diagnosed in his late 40s. All I can think of is the things he will likely miss out on, like his kids graduating high school, etc.
Posted by GulfCoastPoke
Port of Indecision
Member since Feb 2011
1087 posts
Posted on 10/22/19 at 5:39 pm to
quote:

She is happy as frick and she gets to meet new people every day.

Don't tell me about people's family as if that moves the needle, I would much rather see her like this


Judging from your brashness I’m guessing you’ve never seen a patient in the later stages...
Posted by soccerfüt
Location: A Series of Tubes
Member since May 2013
65528 posts
Posted on 10/22/19 at 5:42 pm to
quote:

The company now says a new analysis of more results suggest that the drug helped reduce a decline of thinking skills at the highest dose.
Spray it on the PoliBoard at 100x the recommended dosage level and maybe it’ll help a bit.
Posted by gthog61
Irving, TX
Member since Nov 2009
71001 posts
Posted on 10/22/19 at 5:46 pm to
quote:

Alzheimers patients suffer like crazy. They have no idea wtf is going on and are constantly on edge and terrified.


and they realize bit by bit things they will never be able to do again over a period of years

A big reason I am not too concerned about being fat is I would prefer a massive heart attack to either alzheimer's or cancer, having experienced a parent with each of them.
Posted by Melvin
Member since Apr 2011
23535 posts
Posted on 10/22/19 at 5:47 pm to
quote:

Yeah, that makes me want it even more knowing it won't hurt. I have a grandma that thinks Joe Burrow is her son and hopes he wins the Heisman. She is happy as frick and she gets to meet new people every day.
I work with these people every day and have a family member living with dementia right now. Get back to us in a year or two and tell me how cute you think it is. Dumbass
Posted by dbeck
Member since Nov 2014
29449 posts
Posted on 10/22/19 at 5:48 pm to
quote:

the company earlier this year stopped two studies of the drug when partial results suggested it was not likely to be successful.

I think I remember that happening.
Posted by SEC. 593
Chicago
Member since Aug 2012
4040 posts
Posted on 10/22/19 at 5:54 pm to
You've never worked with the FDA if you think it's owned by big Pharma.
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