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re: Scientists find no evidence of depression being caused by "chemical imbalances" in brain
Posted on 7/27/22 at 10:32 am to lsu13lsu
Posted on 7/27/22 at 10:32 am to lsu13lsu
quote:
Irrelevant because the study is about SSRI's. Which is a highly prescribed group of drugs.
But it is relevant because the 'chemical imbalance' hypothesis is based on catecholamines.
0
Posted on 7/27/22 at 10:34 am to RollTide1987
quote:
“The popularity of the ‘chemical imbalance’ theory of depression has coincided with a huge increase in the use of antidepressants. Prescriptions for antidepressants have risen dramatically since the 1990s, with one in six adults in England and 2% of teenagers now being prescribed an antidepressant in a given year.
So when I started anti-depressants they legit did nothing good for me, the side effects were so bad I got suicidal by just quitting the meds. No one told me that could be a side effect and I ended up being hospitalized. Because why wouldn't anti-depressants cause people to be suicidal.
BUT I never took them because there was a rise in popularity of having a "chemical imbalance" Something was off in my body and it needed to be fixed. Unfortunately, I just had a crap doctor that was like well its a grab bag of drugs so lets see if this works.
I still have crazy anxiety, but have found other ways to help that.
I am still a believer in a chemical imbalance being in place.
Yes, I could work out more or eat better before all the haters come in saying that is all you have to do to make things better.
Posted on 7/27/22 at 10:35 am to lsu13lsu
quote:It is not irrelevant because the title says the following
quote:
What about norepinephrine, dopamine, glutamate?
Irrelevant because the study is about SSRI's. Which is a highly prescribed group of drugs
quote:Norepinephrine, Dopamine and glutamate are all "chemicals" in the brain that are proposed to modulate mood. The study only discusses serotonin.
Scientists find no evidence of depression being caused by "chemical imbalances" in brain
Posted on 7/27/22 at 10:37 am to Jim Rockford
quote:
I posted this in the other thread about the same article when it was posted last week. Before starting on Abilify My wife had crippling panic attacks and depression so severe that the tasks of daily living were almost too much for her. Over the course of about ten days it stopped the panic attacks completely and helped her depression so much that she's able to function as an adult. Maybe they don't understand the mechanism like they thought. Maybe it's over prescribed. But for someone with severe depression, these medicines are lifesavers. People with Agendas are going to misinterpret this study, people will go off their meds, and people will die.
I’m man enough to admit that at one point I got on Lexapro, an SSRI, for about a year and it changed the trajectory of my life forever.
I was able to turn things around and learn healthy habits and then ween off the medication.
It’s been years that I’ve been off now and I don’t take anything anymore, my life is in such a great place and my mind and mental health is as good as it’s ever been.
I truly credit that drug for saving my life/allowing me to function in a manner to help me help myself back onto the right path.
Posted on 7/27/22 at 10:38 am to HoustonChick86
quote:
Yes, I could work out more or eat better before all the haters come in saying that is all you have to do to make things better.
That’s a lie that they tell themselves as confirmation of what they’re doing. Does it help? I’m sure to some degree, but it’s far from a “cure” for depression.
Posted on 7/27/22 at 10:41 am to 225bred
quote:
I’m man enough to admit that at one point I got on Lexapro, an SSRI, for about a year and it changed the trajectory of my life forever.
I was able to turn things around and learn healthy habits and then ween off the medication.
It’s been years that I’ve been off now and I don’t take anything anymore, my life is in such a great place and my mind and mental health is as good as it’s ever been.
I truly credit that drug for saving my life/allowing me to function in a manner to help me help myself back onto the right path.
So it wasnt the drugs. It was you doing something about your life.
Just like it is for anyone no matter what drugs they did or did not take.
Since we are finding out the drugs do nothing, thats all it comes down to.
This post was edited on 7/27/22 at 10:42 am
Posted on 7/27/22 at 10:41 am to HoustonChick86
quote:
Yes, I could work out more or eat better before all the haters come in saying that is all you have to do to make things better.
I found it was more that cured my anxiety/depression.
Working out
Eating better
Sunshine
Get off Social Media
Most importantly: Stop lying to myself and others. Stop committing/agreeing to do things I couldn't do (Just say No to people). Take responsibility for my actions.
That last part literally changed my life. When I talk to so many others that are going through depression and anxiety that last part is the primary thing for them too.
This post was edited on 7/27/22 at 10:42 am
Posted on 7/27/22 at 10:41 am to RollTide1987
quote:
Scientists find no evidence of depression being caused by "chemical imbalances" in brain
Thereby making SSRIs completely useless when it comes to combatting depression.
Spoken like a complete fricking moron.
This study confirms what's been known for decades. This isn't exactly new. The mechanism of action for many psychotropic drugs is unknown but their general effectiveness however is unquestionable.
Research has shown time and again, they work. Researchers just don't know how they work, you fricking dumdum.
Practically all credible study results say something akin to this. The drugs are thought to exert an influence on serotonin levels. It's never been confirmed and now we have a study that simply says it.
No respectable study has ever suggested they don't treat depression.
This post was edited on 7/27/22 at 10:43 am
Posted on 7/27/22 at 10:42 am to Pandy Fackler
quote:
Spoken like a complete fricking moron.
This study confirms what's been known for decades. This isn't exactly new. The mechanism of action for many psychotropic drugs is unknown but their general effectiveness however is unquestionable.
Research has shown time and again, they work. Researchers just don't know how they work, you fricking dumdum.
Practically all study results say something akin to this. the drugs are thought to exert an influence on serotonin levels. It's never been confirmed and now we have a study that simply says it.
No respectable study has ever suggested they don't treat depression.
Researchers don't know how they work they just work dumdum. Hilarious.
They could largely work due to the placebo effect.
Posted on 7/27/22 at 10:42 am to RollTide1987
These drugs are literally a lifesaver for many people and do miracles to treat depression and other issues, whatever the mechanism.
Posted on 7/27/22 at 10:44 am to lsu13lsu
quote:
Researchers don't know how they work they just work dumdum. Hilarious.
They could largely work due to the placebo effect.
Another complete fricking helmet head. This is the OT. Why am I not surprised.
Posted on 7/27/22 at 10:45 am to lsu13lsu
quote:
They could largely work due to the placebo effect.
This is why we have placebo-controlled trials. That way you don't have to hand-wave on a forum about it. Oh, wait.
Posted on 7/27/22 at 10:45 am to High C
quote:
That’s a lie that they tell themselves as confirmation of what they’re doing. Does it help? I’m sure to some degree, but it’s far from a “cure” for depression.
Because they've never been legit depressed.
Yes, a healthy lifestyle goes a long ways, but does working out really help when I was thinking of cutting my wrists. NOPE.
Sorry, this is a very near to my heart topic after losing my sister to suicide from depression. The meds didn't help her either, FWIW. But there was something off in her brain. A chemical imbalance.
Posted on 7/27/22 at 10:46 am to shutterspeed
quote:
These drugs are literally a lifesaver for many people and do miracles to treat depression and other issues, whatever the mechanism.
They absolutely are and I can promise you alot of these OT smooth brains know someone who has gotten better on them. They just don't know they know them.
Posted on 7/27/22 at 10:48 am to Caraway Rye
quote:
So it wasnt the drugs. It was you doing something about your life. Just like it is for anyone no matter what drugs they did or did not take. Since we are finding out the drugs do nothing, thats all it comes down to.
Whatever you say man. I’m not going to argue with a random person on the internet about my real life experiences and feelings.
Think whatever you want, have a nice day
Posted on 7/27/22 at 10:48 am to lsu13lsu
quote:Are the side effects placebo too? The meds are active and have genuinely helped many. They've also been useless for many.
They could largely work due to the placebo effect
Posted on 7/27/22 at 10:48 am to Jim Rockford
quote:
I posted this in the other thread about the same article when it was posted last week. Before starting on Abilify
My wife had crippling panic attacks and depression so severe that the tasks of daily living were almost too much for her. Over the course of about ten days it stopped the panic attacks completely and helped her depression so much that she's able to function as an adult.
Maybe they don't understand the mechanism like they thought. Maybe it's over prescribed. But for someone with severe depression, these medicines are lifesavers. People with Agendas are going to misinterpret this study, people will go off their meds, and people will die.
This man gets it.
Posted on 7/27/22 at 10:49 am to HoustonChick86
quote:
Sorry, this is a very near to my heart topic after losing my sister to suicide from depression. The meds didn't help her either, FWIW. But there was something off in her brain. A chemical imbalance.
Genetics, of course. Either of your parents have issues? My son is in his early twenties and is beginning to have the same issues that I have/had, and it breaks my heart.
Posted on 7/27/22 at 10:52 am to Jim Rockford
quote:
Maybe they don't understand the mechanism like they thought. Maybe it's over prescribed. But for someone with severe depression, these medicines are lifesavers. People with Agendas are going to misinterpret this study, people will go off their meds, and people will die.
The information needs to come out. No one is saying there are not people with brain issues. But, should everyone in this country be on the border of mental illness and normal? Should so many be prescribed?
I don't believe in hiding the truth because it is painful. This information needs to come out.
Posted on 7/27/22 at 10:52 am to lsu13lsu
quote:
Researchers don't know how they work they just work dumdum. Hilarious.
That's true for lots of things in medicine. We know they work but don't know how.
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