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re: Ozempic maker Novo Nordisk surges past Tesla with market value of $566B

Posted on 3/7/24 at 12:05 pm to
Posted by BluegrassBelle
RIP Hefty Lefty - 1981-2019
Member since Nov 2010
108047 posts
Posted on 3/7/24 at 12:05 pm to
quote:

The interesting thing about Ozempic is that it seems to stop or reduce compulsive behavior, so the desire to overeat goes away. Could have applications in treating other compulsive behaviors.


They've started utilizing it therapeutically for eating disorders because it reduces binge eating compulsions.

Considering the physical harm that binging/purging can do to a body, it's a net gain if it treats the binging/purging. Eating Disorders like that have a high mortality rate.
Posted by lsu777
Lake Charles
Member since Jan 2004
38079 posts
Posted on 3/7/24 at 12:05 pm to
quote:

negatively impact body composition (muscle/fat ratio).


wrong

quote:

Yeah I'm not so sure about this. If you tank your protein intake, then yeah.


correct

the drugs are actually anti catabolic slightly and we have known that for better part of a decade

problem is way way too many ramp the dose too quickly and put themselves in way too steep of a deficit for the medicine to overcome and dont priortize protein. thats the downside of.....well people just being people


people are dumb AF and do dumb shite. any severe deficit without prioritizing protein and resistance training will lead to this. medicine or no medicine.


but the medicine itself does not negatively impact body comp, got studies proving that when people go on it, if they do what i said above...they lose muscle slower than someone on placebo and the same diet/regiment.
Posted by Oates Mustache
Member since Oct 2011
26630 posts
Posted on 3/7/24 at 12:06 pm to
quote:

murders a percentage of people’s digestive systems and they have to wear colostomy bags the rest of their lives


This is ridiculous. Do you have even a smidgen of evidence to show this? Some of you are idiots in this thread.
Posted by jcaz
Laffy
Member since Aug 2014
19301 posts
Posted on 3/7/24 at 12:06 pm to
quote:

Before all the crazy comments, I know of 3 people that used it, dropped a ton of weight, and also changed their lifestyle completely. They are now fitness fanatics.

I’m hoping this is what we are mostly seeing in 10 years time. And not the massive health crisis as a result of it
Posted by MoarKilometers
Member since Apr 2015
21129 posts
Posted on 3/7/24 at 12:08 pm to
quote:

and also changed their lifestyle completely.

Chronic diarrhea is life changing.
Posted by lsu777
Lake Charles
Member since Jan 2004
38079 posts
Posted on 3/7/24 at 12:08 pm to
quote:

This is ridiculous. Do you have even a smidgen of evidence to show this? Some of you are idiots in this thread.


they are just going to bring up an article that interviews 1 or 2 people etc

the OT is fricking dumb AF when it comes to these drugs and what is funny is 99% of the posters that comment negatively could and should be using the medicine as they are all overweight based on the BMI threads.

bunch of fat fricks complaining about people being fat but also complaining about other fat people using medicine to no longer be fat

Posted by Aubie Spr96
lolwut?
Member since Dec 2009
44439 posts
Posted on 3/7/24 at 12:09 pm to
quote:

This is a good watch.



Thanks for posting.
Posted by lsu777
Lake Charles
Member since Jan 2004
38079 posts
Posted on 3/7/24 at 12:10 pm to
quote:

Chronic diarrhea is life changing.



comes from lack of fiber in the diet. metamucil will do the trick for 90% of people on the drug and yes i realize fiber normally sucks water into the digest tract to easy shits...but in this case the pysllium husk does a good job of bulking up the bowel movements to allow them to become regular.
Posted by BluegrassBelle
RIP Hefty Lefty - 1981-2019
Member since Nov 2010
108047 posts
Posted on 3/7/24 at 12:11 pm to
quote:

This is ridiculous. Do you have even a smidgen of evidence to show this? Some of you are idiots in this thread.


There's folks rightfully being skeptical about potential side effects down the road.

Then there's people openly wishing that people die or have major health issues on it. But will also complain relentlessly about fat people being a drag on society. You can't win apparently.
This post was edited on 3/7/24 at 12:12 pm
Posted by goofball
Member since Mar 2015
17353 posts
Posted on 3/7/24 at 12:11 pm to
quote:

Novo Nordisk on Thursday surpassed Tesla in market valuation after the maker of the popular weight-loss drug Wegovy and Ozempic announced positive early trial data for a highly anticipated new obesity drug.


So these are just those diabetes treatments that are rebranded and approved for weight loss, thus can be covered by insurance?

Posted by lsu777
Lake Charles
Member since Jan 2004
38079 posts
Posted on 3/7/24 at 12:11 pm to
quote:

This is a fascinating aspect of it that I'd love to know more about. That is a totally different conversation.


was there something specific you were looking for in regards to this?


quote:

Mounjaro can reduce the desire to drink alcohol because it stimulates the brain's reward center. When Mounjaro binds to GIP and GLP-1 receptors, dopamine may have a harder time attaching to them. This can lead to less dopamine triggering the reward system, which may mean less of a desire to drink alcohol.
According to a study by Virginia Tech's Fralin Biomedical Research Institute, drugs used to treat Type 2 diabetes and obesity can reduce alcohol cravings. The study also found that the drugs were effective in reducing alcohol consumption in animal models



LINK

LINK
This post was edited on 3/7/24 at 12:14 pm
Posted by Odysseus32
Member since Dec 2009
10048 posts
Posted on 3/7/24 at 12:12 pm to
(no message)
This post was edited on 3/12/24 at 3:51 pm
Posted by dgnx6
Member since Feb 2006
89829 posts
Posted on 3/7/24 at 12:12 pm to
quote:

they are just going to bring up an article that interviews 1 or 2 people etc

the OT is fricking dumb AF when it comes to these drugs and what is funny is 99% of the posters that comment negatively could and should be using the medicine as they are all overweight based on the BMI threads.

bunch of fat fricks complaining about people being fat but also complaining about other fat people using medicine to no longer be fat




I am not overweight, im just saying the bill is coming due.


Posted by CatfishJohn
Member since Jun 2020
20344 posts
Posted on 3/7/24 at 12:12 pm to
quote:

problem is way way too many ramp the dose too quickly and put themselves in way too steep of a deficit for the medicine to overcome and dont priortize protein. thats the downside of.....well people just being people


people are dumb AF and do dumb shite. any severe deficit without prioritizing protein and resistance training will lead to this. medicine or no medicine.


You're arguing semantics. People are dumb and lazy, especially in this country, and they won't make proper diet and exercise changes while using this for weight loss and will have negative body composition side effects because of it. Those same people would never have caloric deficits if it weren't for the drug.
Posted by Dizz
Member since May 2008
16149 posts
Posted on 3/7/24 at 12:12 pm to
quote:

They will have zero problems paying out a few hundred million.



If this medication goes south, they would be paying much much more than a few 100million.
Posted by CatfishJohn
Member since Jun 2020
20344 posts
Posted on 3/7/24 at 12:13 pm to
quote:

was there something specific you were looking for in regards to this?



I'll ask a doctor. I work with a GI doc a lot buying up medical clinics, that's who I've discussed Ozempic with.
Posted by Scuttle But
Member since Nov 2023
1301 posts
Posted on 3/7/24 at 12:14 pm to
quote:

That's about 33 lbs for a 250 lb person. Significant but I wouldn't call it a miracle cure.

quote:

you also change your lifestyle, it's significantly more. One friend dropped 85lbs, another is in the 120lb range


So if I wanted to drop about 20-25 lbs without changing my lifestyle Ozempic would work for me?
Posted by Jcorye1
Tom Brady = GoAT
Member since Dec 2007
76373 posts
Posted on 3/7/24 at 12:15 pm to
quote:

That's about 33 lbs for a 250 lb person. Significant but I wouldn't call it a miracle cure.


That's 3 months, they are losing 10 pounds a month basically, which is impressive.
Posted by CatfishJohn
Member since Jun 2020
20344 posts
Posted on 3/7/24 at 12:17 pm to
quote:

So if I wanted to drop about 20-25 lbs without changing my lifestyle Ozempic would work for me?



If your definition of success is losing weight without changing lifestyle, regardless of other issues that may arise, yes.

Posted by Uncle JackD
Member since Nov 2007
59567 posts
Posted on 3/7/24 at 12:18 pm to
quote:

So if I wanted to drop about 20-25 lbs without changing my lifestyle Ozempic would work for me?
Not likely. Not for long anyway. You’ll be miserable as frick if you polish off a large pizza and mountain dew.

I know several who have gotten on GLPs and still failed. It helps bigly, but you’ve still gotta put in work or you’ll be back at square one, just with less $.
This post was edited on 3/7/24 at 12:20 pm
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