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re: Ozempic maker Novo Nordisk surges past Tesla with market value of $566B
Posted on 3/7/24 at 11:51 am to Oates Mustache
Posted on 3/7/24 at 11:51 am to Oates Mustache
(no message)
This post was edited on 3/12/24 at 3:50 pm
5
Posted on 3/7/24 at 11:51 am to ShoeBang
quote:
Just wish more people did it the right way.
why is using the drug not the right way? you realize it forces you to change your lifestyle right?
i dont hate either way but i do hate ignorant comments from those that have zero clue to how the medicine works.
Posted on 3/7/24 at 11:53 am to Ingeniero
quote:
I bet the doctors don't care. Telling them to "lose weight or you're going to die" clearly isn't working, so why not put them on the magic pill that literally forces them to not eat? If they're going to have bad habits at least they'll be physically restricted from one of them: engorging themselves. And I'm kind of inclined to agree. Why have fat people with bad habits when you can make them slightly less fat and keep the rest of the habits?
IMO the larger issue is these "weight loss spas" that are popping everywhere that is prescribing these meds without any real education on what you should be doing on them.
We just had one open in our office complex and we decided to walk down to check it out. They want to put you on Ozempic while also having you take B12 shots and a host of other "supplements" in their regiment. No discussion of changes of lifestyle, eating habits, etc. Just come pay $2000 a month for our "cocktail".
The fiance is diabetic and went on Oxempic several months ago per his doctor. It's allowed him to come off a ton of the meds he was on, which has reduced a whole host of side effects and potential risks from those meds. But he was also educated by his endocrinologist on exercising and changing habits while using it. So he hasn't had the bowel issues or muscle loss issues others have had.
Posted on 3/7/24 at 11:54 am to CatfishJohn
quote:
negatively impact body composition (muscle/fat ratio). I
Yeah I'm not so sure about this. If you tank your protein intake, then yeah.
This post was edited on 3/7/24 at 11:56 am
Posted on 3/7/24 at 11:55 am to Jim Rockford
quote:
That's about 33 lbs for a 250 lb person. Significant but I wouldn't call it a miracle cure.
If they can maintain their weight loss, that’s life changing for some people. Also, if more people dropped significant weight, it has to be a net positive for our healthcare system
Posted on 3/7/24 at 11:55 am to Oates Mustache
quote:
negatively impact body composition (muscle/fat ratio). I
Yeah I'm not so sure about this.
For people that don't supplement with diet and exercise changes* is the caveat to that comment, which in our lazy country, is likely a huge portion of the people taking the drug.
Posted on 3/7/24 at 11:56 am to RLDSC FAN
quote:
Novo Nordisk on Thursday surpassed Tesla in market valuation after the maker of the popular weight-loss drug Wegovy and Ozempic announced positive early trial data for a highly anticipated new obesity drug.
Ah, i didnt realize the insulin providers in this country also came out with these drugs.
Makes sense, get the money from the fatties and now take it from the ones wanting to lose weight.
Smart.
Posted on 3/7/24 at 11:56 am to lsu777
quote:
why is using the drug not the right way? you realize it forces you to change your lifestyle right?
So once you drop 20lbs and decide to stop taking it your lifestyle is permanently changed? That’s the point. I’m not talking about Fatty McFatfat that let himself go so far that it’s out of control here. I’m talking about travel ball moms fresh off a divorce that use it temporarily to drop just enough weight to bag another schmuck to facilitate their lifestyle
Posted on 3/7/24 at 11:58 am to dgnx6
quote:
Ah, i didnt realize the insulin providers in this country also came out with these drugs.
Makes sense, get the money from the fatties and now take it from the ones wanting to lose weight.
Smart.
They were initially developed specifically for diabetes to reduce the usage of injectable daily insulin. It was developed as a once-a-week alternative (and it works for that pretty well).
When they saw it was also encouraging weight loss, they started using it off label for weight loss.
Posted on 3/7/24 at 11:59 am to RLDSC FAN
The interesting thing about Ozempic is that it seems to stop or reduce compulsive behavior, so the desire to overeat goes away. Could have applications in treating other compulsive behaviors.
Posted on 3/7/24 at 11:59 am to Odysseus32
quote:
I lost my weight the old fashioned way, restricting calories, exercising, and generally changing my relationship with food. And I think that is where I start to get a little pissy. I see family members who are always looking for a workaround take it, and they fail to change their relationship with food.
thats the thing though the medicine forces you to change your habits or it will punish the frick out of you
quote:
That's out the window with these drugs, which is, whether people realize it or not, the real point of losing weight.
thats not even close to true
quote:
I've resigned to understanding that its better for society, but it leaves a bad taste in my mouth that these people aren't going through the actual self-discipline modes needed to lose weight traditionally.
how does it affect you at all that it should affect your mood?
thats like people who lift getting mad steroid users get better gains. it reeks of jealousy and it not a good look.
i dont take the medicine because I personally dont need to. I also realize i dont get whats referred to as food noise and dont have an addictive personality to begin with. But i also understand everyone is not me.
i think the medicine is a miracle drug. but not just for the weight loss aspects but its ability to down regulate desires in addicts, especially alcoholics
but that does come with significant unwanted issues, especially for those in a committed relationship as the drugs and class of drugs are known(atleast at highest dose) to affect dopamine sensors so much that it down regulates sex drive to the point many women can no longer even orgasm and many end up without the slightlest desire for sex.
now been told and read stories of those same people regaining that drive as they lowered the dose to a maintenance dose.
unforeseen how that affects addictions though.
if you are an alcoholic though...even if thin, you should absolutely try the drug if you have desire to stop.
Posted on 3/7/24 at 12:00 pm to CatfishJohn
quote:
For people that don't supplement with diet and exercise changes* is the caveat to that comment, which in our lazy country, is likely a huge portion of the people taking the drug.
I edited my post. I get that. My anecdote so far has been a positive one with my friends that are on it. But in the beginning I was on their asses about keeping their protein intake high while they are on it. Obviously, they are also weight lifting and found cardio too.
This post was edited on 3/7/24 at 12:04 pm
Posted on 3/7/24 at 12:00 pm to Odysseus32
quote:
And I think that is where I start to get a little pissy. I see family members who are always looking for a workaround take it, and they fail to change their relationship with food. Just losing weight isn't the thing that's going to change it for most everyone. You have to go through the struggle of not being hungry but wanting food and wondering why
I think this is where I am too. I've never had to lose weight, so I don't know the difficulty of it. But I do know the feeling of discipline and showing up every day to reach fitness goals. I wonder what studies will show for people who use the drugs to kickstart a lifestyle change vs people who use it to do the bare minimum and girl all the calories they can through Twinkies and Popeyes until the pill stops them
Posted on 3/7/24 at 12:01 pm to ShoeBang
quote:
So once you drop 20lbs and decide to stop taking it your lifestyle is permanently changed? That’s the point. I’m not talking about Fatty McFatfat that let himself go so far that it’s out of control here. I’m talking about travel ball moms fresh off a divorce that use it temporarily to drop just enough weight to bag another schmuck to facilitate their lifestyle
most dont stop taking it. they lower it slowly to a maintenance dose then slowly cut that dose in half over time too.
then maybe, maybe get off but its after a very slow process or should be
now like i said in my OG post, there will be people like you mentioned, who abuse the drug. thats what peopele do.
Posted on 3/7/24 at 12:01 pm to lsu777
quote:
down regulate desires in addicts, especially alcoholics
This is a fascinating aspect of it that I'd love to know more about. That is a totally different conversation.
Posted on 3/7/24 at 12:01 pm to BluegrassBelle
quote:
They were initially developed specifically for diabetes to reduce the usage of injectable daily insulin. It was developed as a once-a-week alternative (and it works for that pretty well).
When they saw it was also encouraging weight loss, they started using it off label for weight loss.
im not saying the drug is bad, it's just that Novo and Lilly overcharge for insulin. Now they are getting even more money off this. Just nickel and diming every fatty and the tax payer.
quote:
Novo and Eli Lilly are so far the leaders in the obesity drug market, forecast by analysts to be worth $100 billion by 2030.
quote:
According to a Bloomberg analysis of 2022 data, Medicaid spent $7.9 billion on GLP-1s in 2022 pre-rebates from manufacturers, and reimbursements are expected to rise this year as more people seek out the drugs.
Connecticut was quick to experience the impact of weight loss drugs on its economy last year. Politico reported in November that the state's employee health plan was set to spend $30 million on drugs like Ozempic and Wegovy. Comptroller Sean Scanlon told BI that that was up from $8 million in 2020.
This post was edited on 3/7/24 at 12:10 pm
Posted on 3/7/24 at 12:02 pm to concrete_tiger
Just like Purdue Pharm and others, pharm companies have lawsuit payouts built in to the production of the drugs.
So when Ozempic murders a percentage of people’s digestive systems and they have to wear colostomy bags the rest of their lives, they’ll gladly pay out that $300 million class action settlement. They made $10 billion from the drug.
So when Ozempic murders a percentage of people’s digestive systems and they have to wear colostomy bags the rest of their lives, they’ll gladly pay out that $300 million class action settlement. They made $10 billion from the drug.
Posted on 3/7/24 at 12:04 pm to BeepBopBoop
quote:
So when Ozempic murders a percentage of people’s digestive systems and they have to wear colostomy bags the rest of their lives, they’ll gladly pay out that $300 million class action settlement. They made $10 billion from the drug.
they estimated $100 billion.
They will have zero problems paying out a few hundred million.
Posted on 3/7/24 at 12:05 pm to Jim Rockford
quote:
That's about 33 lbs for a 250 lb person. Significant but I wouldn't call it a miracle cure.
That’s the problem with averages and their application to individuals.
Certain medications cause weight gain. Specifically, the SSRI class averages a 1lb weight gain. I heard someone explain it more accurately though as “39 people don’t gain any weight, and one person gains 40lbs.”
15% is still also significant. You have pretty major implications on your health by 5-10% weigh drops. The majority of overweight folks could, indeed, fix it with lifestyle changes. Sometimes the medication motivates the change. Sometimes people just depend on the medicine. The former does well. The latter is the reason the average isn’t higher.
Posted on 3/7/24 at 12:05 pm to Jim Rockford
quote:
That's about 33 lbs for a 250 lb person. Significant but I wouldn't call it a miracle cure.
It’s 3 months
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