re: New to the Forum, any other biotech guys on here????

I've never seen someone so angry about others keeping his awful thread on the 1st page. Are you sure you're a long-time lurker? You really don't know how Internet forums work? You have the thinnest skin I've ever seen, and it's very entertaining. You fail to realize your meltdowns are the reason your thread is still getting views. But you have too much hubris to ignore me and others, so you'll continue to get fricked with. I'll bet you respond to this post. I'll even promise to stop posting in your precious thread if you don't respond to me. You and I both know you can't help yourself.

In the meantime, keep pumping away...

kid from another country? wow nice stereotype skills you developed in the backwoods of LA, actually Im old and I'm ashamed to admit it but from hickville of Lafayette, I don't go back ever but thats where my roots are from, where we got guys like the poster above assuming people are just foreigners from a few paragraphs on the internet.....god man I guess all my colleagues were right seriously in all their assumptions about me bc of where Im from and where I went to school, geez man is that how the average person down south thinks????? WOW

LOL damn I grew up down there, went to USL for a little while, graduated from LSU and moved out to northeast and never looked back, thank the lord, if I stayed Id probably be small minded and make assumptions about immigrants like the guy above.

As to the one poster who actually mentioned anything scientific on this page,Sigma, I got much respect for you because of the questions you ask, you clearly are in this field.......

ill say this bro and ill look into those documents thanks, but there is a flip side to this and its this, BLUE CEO seemed adament to make sure his vector wasnt being compared to others because its a different "mechanism", these "mehanisms" are what you learn about in organic chemistry provided you stick it out, they explain biochemical reactions, which is whats taking place here, say, that this lentiviral vector, say these genotoxic events only occur in 1/5000 patients vs what must have been something like 1/100 or maybe even 1/50 patients for these other vectors, say thats true, well then come on come all for the grand licenses to the only way to create gene therapies without having to call up AGIO a few years later, again way to early, just saying, seems possible to me

ill check out those papers and get back to you though, insertion near a known oncogene,oncogenes cause cancer, man HIV one of the best viruses out there, i have faith it in as a vector, Also sans Thomas Reed at Intrexon, these guys to me at BLUE are the best scientists on the planet, I got no issue betting on these guys

man i think and its high risk though man but BLUE does man have $100B potential, i know thats semi irrelevant to this trade, and i would like to hear what other diseases they think would be on the docket to cure, but these treatments produce pure cures, potential endless here and ill never believe that you cant bring the chances of cancer very close to nil eventually, but things like blindness, deafness, etc, i mean these potentially can be cured here thats not just sci fi anymore

you cant say JUNO,BLCM and KITE or other CAR T names have 100B potential, they dont


which is why i think any buyer in the space, the space being biotech not just Gene Therapy, has to have both eyes on bluebird, well see in the coming days/weeks/months/maybe years, if any of this comes true.....only time will tell

another reply by a clear pumper of course

Tigerdebaiter, you've made multiple posts in this thread, not one has been relevant to the topic of the thread, do you just have time to waste in your life? I personally wouldn't waste my time trying to talk to someone about a topic i know nothing about

Yea Im just gonna ignore anyone not referencing science in any way, there are just entirely too many amateur hour guys in this thread doing nothing but trying to egg me on, sigma and no fox are the only people commenting worth replying to and Im giving them my best answer in reply.

Multiple donkeys in this thread for sure, its kinda funny that they repeatedly try to comment on a subject they literally have no insight whatsoever on, but bless their little hearts they're trying really hard to disprove me and my science.

Its cute grown men try so hard, I admire it

As the oncogenesis rate continues to drop, as you point out, the risk of cancer may be worth the chance if you're effectively cured. In that sense maybe BLUE is a good bet.

But what their doing is a little more cell therapy than gene therapy. Correct me if I'm wrong but it appears they are using an ex vivo approach. This is good, as it removes one historical roadblock to gene therapy: delivery toxicity.

IMO gene therapy will never fulfill the expectations from the 90s, for several reasons. However I think there will be specific monogenic diseases where right vector/cell type/ disease combination can be found. Maybe BLUE is close, all I'm saying, and I think you agree, is it's risky. On the plus side, if there's one thing I know about biotech its that people can get rich on hype and potential if the idea is cool and new, or if a great need is met despite some hitches.

(Also FYI the term "mechanism" there is not the pure organic chemistry of DNA/RNA. He means the molecular biology mechanism of the viral action)

He seems to possess some level of scientific knowledge. And one of the reasons that I joined this board was to interact with people who had knowledge in areas and sectors where I did not possess a lot of knowledge. Considering the broad and varied base of professions represented here, it's a great opportunity to learn and share knowledge and ideas, *if you have a willingness to take advantage of it.* But one cannot share what he knows, or learn from others, if he is thin-skinned, petulant or arrogant.

I've seen no indication that he is an actual "trader", in the truest sense. He lacks money management skills, or at least the ability to demonstrate that he has those skills. And other than using whatever scientific knowledge he has as a basis, his fundamental buy signals seem rather haphazard. What are his buy and sell signals? Does he implement any form of technical analysis, or is it strictly fundamental based? When he suggested that another poster sink his nest egg investment money into a biotech (or any) stock, I wondered what sort of money management knowledge he had. Solid portfolio and money management rules are the surest signs of a "real" trader, or even a longer term investor. Buying stocks on a hunch, or even an educated guess, does not a trader make.

Personally, I hope that, in time, he will see that this approach is not working and he dials it down a notch. And then, with a bit less piss & vinegar in his demeanor, begins (truly) interacting with the investors and traders here. There are not many boards like this in the great, mouth-breathing wasteland of the internet- I've looked! Hopefully he will realize that and do some give & take, without the bravado.

I strongly agree with your point about monogenic diseases. I feel like many in molecular biology forget that most traits are polygenic and the interactions between these loci are complex. I think the illumina next generation sequencing platforms are going to do a good job reducing said ignorance. On another note, I think that many of the proposed applications of CRISPER are exciting.

JAg I relay my ideas in a constructive manner but I get upset when guys who have no idea what they're talking about start commenting. I answered every question if you read the thread from Sigma and NOFOX with a deep scientific knowledge, if you read my posts you'll notice I'm not a high school chemistry buff. I know what Im talking about and I get irked when guys start commenting on the topic of biotech stocks when the have no clue what an orphan drug is and why its different from the drug the most retail name they all hold, GILD, sells.

Like I said anyone else, in any industry would have enough of all the horseplay questions bc they're just a waste of time unless you understand this space. That is why I sought out other biotech investors, guys who understood negative EPS, bad balance sheets, etc don't matter bc you're investing in the science and if its good its acquired. I think all 10 stocks I laid out are horrendous if you're a traditional graham investor and only know about balance sheets. Sigma and NOFOX know science like me and low and behold sigma found bluebird interesting, like any real science fan would

I didn't come here with the intent of being rude but immediately people called me a pumper bc I spoke with gusto and passion, sorry I get a hard on for new treatments, like I said I was an orphan drug discoverer, I get wood over treatments, so sue me. I don't like to waste my time, and 95% of posts in this thread were by amateurs commenting on a space they shouldn't have commented on, and sarcastically. I would have answered every question like i did sigma and no fox if everyone else just simply said I don't know this or i don't know that, but these guys stormed me with nonsense about being a pumper, like I could pump a $5B company on a silly LSU message board where the average guy isn't even worth $100k, yea great target market for a pump job.

Anyways Science guys understand these stocks and how they function, regular people do not, I knew if regular people came it would be a headache.....and it was....it shouldn't have been, the 3-4 science guys in this thread have a lot to discuss and we did so eloquently if you read all the Q & A today between me and sigma

I just want people to stick to discussing what they know, I don't go out my way to discuss what I don't know, and I certainly don't go after self proclaimed experts and try to disprove them in fields like energy and banking, that would be silly of me

quote:

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worst of all they all refuse to sit back and learn new things or understand

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Says the guy who came to a money board refusing to talk about money.