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Anyone ever use peptides for treatment of sexual dysfunction?

Posted on 1/31/26 at 5:55 pm
Posted by cbree88
South Louisiana
Member since Feb 2010
10173 posts
Posted on 1/31/26 at 5:55 pm
I’ve heard that there’s some good ones, especially bremelanotide (PT-141)

Anyone ever use this one or any others to improve sexual function?
Posted by LemmyLives
Texas
Member since Mar 2019
14281 posts
Posted on 1/31/26 at 8:37 pm to
You have another thread today on not wanting to do TRT, to use a form of clomiphene. You need to find a new doctor. Go to a TRT clinic, or find one online (I can refer you) and explain the totality of your issues so a long term plan can be developed.

Peptides, in my experience, and those of my neighbors, don't do shite, at least for weight loss, mass building, or recovery. Viagra is cheap, just use it.
This post was edited on 1/31/26 at 8:38 pm
Posted by pwejr88
Red Stick
Member since Apr 2007
37725 posts
Posted on 1/31/26 at 9:18 pm to
quote:

(PT-141)


It’s a shot.
Works for women too.
Makes you horny as hell.
Side effects for some: throwing up
Posted by jtraylor387
Baton Rouge, LA
Member since Oct 2008
228 posts
Posted on 2/1/26 at 2:00 am to
Pt-141 works very well in that department. Major side effect is nausea. Once that passes, major libido for both sexes is there.
Posted by Uncle JackD
Member since Nov 2007
59476 posts
Posted on 2/1/26 at 6:38 am to
After getting your diet and hormones in check, a simple 5mg of cialis a day works like a charm.
Posted by cbree88
South Louisiana
Member since Feb 2010
10173 posts
Posted on 2/1/26 at 9:18 am to
What do you do personally to get your hormones in check?
Posted by Uncle JackD
Member since Nov 2007
59476 posts
Posted on 2/1/26 at 10:26 am to
quote:

What do you do personally to get your hormones in check?
I’ve lost a load of weight, eat clean, lift 4x a week, dropped my BF% from prob 40% to 17%, drink less, prioritize sleep... And on TRT. My boy down there works better than he ever has and the Mrs. Is not complaining a bit.
This post was edited on 2/1/26 at 10:28 am
Posted by GulfSouthTiger
Member since Jun 2025
542 posts
Posted on 2/2/26 at 1:29 pm to
PT-141 works great. Puts you in the mood like a teenager. Don't take too much or it will make you flush and nauseous though
Posted by cbree88
South Louisiana
Member since Feb 2010
10173 posts
Posted on 2/2/26 at 2:02 pm to
Have you used PT-141 personally?
Posted by GulfSouthTiger
Member since Jun 2025
542 posts
Posted on 2/2/26 at 2:04 pm to
Yes. The effects last about 3 days. Haven't done it in a while.
Posted by SETH6180
TEXAS
Member since Feb 2020
941 posts
Posted on 2/2/26 at 2:15 pm to
How much did you take? Curious about dosage.
Posted by GulfSouthTiger
Member since Jun 2025
542 posts
Posted on 2/2/26 at 2:19 pm to
So I took 1 and .75 mg at first and that was too much. Felt like shite the day I took it, but the 2 days after felt fine and got positive effects. I then lowered the dosage to .5 mg and didn't have the negative side effects.
Posted by cbree88
South Louisiana
Member since Feb 2010
10173 posts
Posted on 2/4/26 at 7:09 am to
Any negative consequences of taking PT-141? Can you still function sexually without it?
Posted by lsu777
Lake Charles
Member since Jan 2004
37180 posts
Posted on 2/4/26 at 8:34 am to
yea can make you nauseous and it can give you a boner that wont go away


have you gotten your hormones checked? are you taking cialis 5mg daily for health? are you working out? is your diet in order? is your bodyfat below 20%?

if not, just get some viagra for now and get to work on the above asap.

pt-141 is awesome, especially for libido, especially for her......but its like using a nuclear bomb when a simple BB gun would do the job.
Posted by jose
Member since Feb 2009
29673 posts
Posted on 2/4/26 at 9:12 am to
If you are experiencing as much sexual dysfunction as you post about, you may want to go talk to a doctor in person not over an internet forum.
Posted by GulfSouthTiger
Member since Jun 2025
542 posts
Posted on 2/4/26 at 9:16 am to
quote:

Any negative consequences of taking PT-141? Can you still function sexually without it?
Yeah, it just enhances things in my opinion.

Only negative is that if you take too much, you get really flushed and queezy feeling. That only lasts a few hours, the next day the positive effects still kick in without the flushing and nausea. Just don't take too much and you should be fine. Start with .5 g to see how you feel on it.
This post was edited on 2/4/26 at 9:22 am
Posted by Don Quixote
Member since May 2023
4562 posts
Posted on 2/4/26 at 10:35 am to
we've used PT-141 and it's pretty amazing stuff BUT I'd never recommend it for someone who's first starting out addressing ED issues. As Jack and others have mentioned, start with your weight, activity, diet, blood labs, hormone labs, etc and tadalafil (generic cialis).

I'd characterize PT-141 as in the upper end of the spectrum of treatments, below TriMix and implants being at the extreme. It's fun for when we have a long weekend at the cabin but not for routine use, though I've read some guys who've taken it regularly in microdoses.
Posted by Uncle JackD
Member since Nov 2007
59476 posts
Posted on 2/4/26 at 10:58 am to
I’ve asked the Mrs to try 141 a couple times just for fun, she told me I was out of my mind.
Posted by Don Quixote
Member since May 2023
4562 posts
Posted on 2/4/26 at 11:10 am to
yeah the stars have to align just right for mine to use it and frankly we've seen better benefits for her since she started taking testosterone
Posted by WhiteMandingo
Member since Jan 2016
7552 posts
Posted on 2/4/26 at 11:16 am to
She was going to do that anyway
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