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Tucker makes a very interesting statement regarding SSRI's after humiliating Mark Cuban
Posted on 9/9/25 at 8:27 am
Posted on 9/9/25 at 8:27 am
It is time stamped to begin about 5 seconds prior to the statement. However, knowing a couple of people who are prescribed them, it certainly opened my mind to what is occurring and weighing the advantages or disadvantages is no longer paramount.
11
Posted on 9/9/25 at 9:16 am to Timeoday
From Zoloft’s package insert:
Science.
quote:
Sertraline selectively inhibits the reuptake of serotonin (5-HT) at the presynaptic neuronal membrane, thereby increasing serotonergic activity. This results in an increased synaptic concentration of serotonin in the CNS, which leads to numerous functional changes associated with enhanced serotonergic neurotransmission.19,21 These changes are believed to be responsible for the antidepressant action and beneficial effects in obsessive-compulsive (and other anxiety related disorders). It has been hypothesized that obsessive-compulsive disorder, like depression, is also caused by the disregulation of serotonin.16
Science.
Posted on 9/9/25 at 9:31 am to Timeoday
quote:Tucker has no idea whatsoever as to WTF he's talking about here. None! Are SSRIs overprescribed? Perhaps in the US, they are. Reason? If a person shows up in a US doctors office complaining of depression, and little aside from counselling is done, then if the person commits suicide (for whatever reason), in the US medmal system an ambulance chaser will ring the register.
Tucker makes a very interesting statement regarding SSRI's after humiliating Mark Cuban
Combine that with a regime of OBLIGATORY targeted depression-related questions required by medicare for every patient, whether or not they remotely appear depressed, and you have a set up for overprescription.
Every medical intervention, even an aspirin, comes with risk. So overprescription of anything can be problematic. But the categorical SSRI-OMG!-OMG! hysteria is unwarranted.
This post was edited on 9/9/25 at 9:32 am
Posted on 9/9/25 at 9:34 am to the808bass
quote:Yes. In this case it is.
Science.
Posted on 9/9/25 at 9:35 am to NC_Tigah
quote:
Tucker has no idea whatsoever as to WTF he's talking about here. None! Are SSRIs overprescribed? Perhaps in the US, they are. Reason? If a person shows up in a US doctors office complaining of depression, and little aside from counselling is done, then if the person commits suicide (for whatever reason), in the US medmal system an ambulance chaser will ring the register. Combine that with a regime of OBLIGATORY targeted depression-related questions required by medicare for every patient, whether or not they remotely appear depressed, and you have a set up for overprescription. Every medical intervention, even an aspirin, comes with risk. So overprescription of anything can be problematic. But the categorical SSRI-OMG!-OMG! hysteria is unwarranted.
Posted on 9/9/25 at 9:44 am to Timeoday
Weak Americans can't cope with their menial 9-5 without some dope.
I get medicating combat vets or trauma victims (even that should be done carefully). But regular use of a gym membership or some real physical exertion combined with hobbies that do not instantly gratify would go a long way for most people who doctors choose to medicate. Food as well. Eating real food and not processed and petroleum-laden food products helps overall well-being to include mental.
I get medicating combat vets or trauma victims (even that should be done carefully). But regular use of a gym membership or some real physical exertion combined with hobbies that do not instantly gratify would go a long way for most people who doctors choose to medicate. Food as well. Eating real food and not processed and petroleum-laden food products helps overall well-being to include mental.
Posted on 9/9/25 at 9:50 am to NC_Tigah
quote:
But the categorical SSRI-OMG!-OMG! hysteria is unwarranted.
The science says that not only do SSRIs not outperform placebo, unlike placebo, SSRIs come with a host of real negative side effects.
Posted on 9/9/25 at 9:56 am to NC_Tigah
Sounds like perhaps your caveats may speak to more of the problem than what Tucker is generally saying - but could logically lead to people to draw such generalized conclusions. I don’t pretend to possess ANY scientific knowledge on this topic, though.
Posted on 9/9/25 at 10:26 am to blackinthesaddle
quote:That is categorically false. For major depression, the kind of disease indicative of the neurochemical imbalance SSRIs are designed to address, SSRIs certainly outperform placebo and can be life savers. For transient or situational depression, which they are not suited for, they are unhelpful.
The science says that not only do SSRIs not outperform placebo
Posted on 9/9/25 at 10:26 am to Timeoday
if he really insisted on only treatments that correct the underlying etiology of the disease, he'd be restricting us to a relatively short list of medications. I suspect he wouldn't really be advocating that so I think this is a kind of a special pleading for prescribing for psych disorders (or rather not doing so) in a way that no one would tolerate for other health problems, but that's an unfortunately common attitude, though thankfully less than it used to be.
This post was edited on 9/9/25 at 10:28 am
Posted on 9/9/25 at 10:43 am to NC_Tigah
quote:
Yes. In this case it is.
quote:
numerous functional changes associated with enhanced serotonergic neurotransmission.
These changes are believed to be
It has been hypothesized
I am convinced.
Posted on 9/9/25 at 10:52 am to Timeoday
I am actually at the at the event and Tucker hit Cuban pretty hard on Ukraine.
Posted on 9/9/25 at 10:55 am to the808bass
Not just SSRI's lithium's been working for >60 years and it's not really understood why. Lots of non psych-meds are like this too - metformin cuts diabetes deaths, anesthetics allow for surgery & and people argue about how they work. The body is weirder than our textbooks for a lot of things we wouldn't think of skipping for a home remedy.
Posted on 9/9/25 at 10:59 am to taeemwar
The amount of retards in this thread is hilarious.
I'd love for those thinking SSRIs are only for "combat vets or trauma suffers" to live a week with any type of panic disorder.
Feeling like you're having a heart attack almost every day for no reason, sleep paralysis, avoidance of certain situations due to the unknown outcome if an attack were to occur, etc.
I wouldn't wish that on my worst enemy.
Gotta love weak and crappy genetics, but the recent hot takes on SSRI meds shows how retarded and gullible most people are that love online and believe everything their side says
All the knowledge at our fingertips and people continue to devolve into idiots online.
Guess that's the status quo here though
I'd love for those thinking SSRIs are only for "combat vets or trauma suffers" to live a week with any type of panic disorder.
Feeling like you're having a heart attack almost every day for no reason, sleep paralysis, avoidance of certain situations due to the unknown outcome if an attack were to occur, etc.
I wouldn't wish that on my worst enemy.
Gotta love weak and crappy genetics, but the recent hot takes on SSRI meds shows how retarded and gullible most people are that love online and believe everything their side says
All the knowledge at our fingertips and people continue to devolve into idiots online.
Guess that's the status quo here though
Posted on 9/9/25 at 11:04 am to Go_Dawgs
Glad you found something that helped. I think the teachable point for skeptical folks here is that Tucker is using a huckster move to discredit health practice that they rely on every day. Most of what you know works in your drugstore doesn't treat the etiology of your disease. But it still works.
Medicine often proves a treatment works before it fully understands why. That’s not failure. It’s how science moves forward: observe effect --> use it responsibly --> work to explain the biology.
Medicine often proves a treatment works before it fully understands why. That’s not failure. It’s how science moves forward: observe effect --> use it responsibly --> work to explain the biology.
Posted on 9/9/25 at 11:12 am to Go_Dawgs
While I whole heartedly agree that these meds are likely over prescribed (and quite honestly, for too long as well) What is facing providers every day is patient after patient paying for a service, coming in and discussing a problem and wanting a solution. While we do discuss going outside, taking a walk, journaling, exercise, seeing a counselor, many patients scoff at that. They want a quick fix. And this isn’t just anxiety/depression. This is sleep, weight loss, etc. So before you point the finger at the provider, remember we didn’t bring them out of their homes to put them on meds. In a perfect world, we would have a medical home model with counseling in house that is required before getting on or in addition to these meds. It’s simply not reality.
Posted on 9/9/25 at 11:21 am to Timeoday
Among the many fatigues I have Tucker fatigue is just another
Posted on 9/9/25 at 11:26 am to Timeoday
Every 2nd generation SSRI has a black box warning.
They cause SI when taken regularly. When people are off their meds is when they usually commit violence.
So you are suicidal on the meds, and you become homicidal when you try to stop taking them?
Awesome.
They cause SI when taken regularly. When people are off their meds is when they usually commit violence.
So you are suicidal on the meds, and you become homicidal when you try to stop taking them?
Awesome.
Posted on 9/9/25 at 11:30 am to 10tiger
quote:
So before you point the finger at the provider
"Don't blame us! The patient WANTS the meds! What are we supposed to do? Say 'No'?"
Well, motherfricker your license makes you the gatekeeper whether you like it or not. I suggest that if you can't tell a patient "No" then you need another profession, Nancy. First, do no harm.
Posted on 9/9/25 at 11:33 am to Tmo Sabe
quote:
Weak Americans can't cope with their menial 9-5 without some dope.
This is about as ignorant of a low IQ take as one can have. Take some time to educate yourself on the use of SSRI's and what conditions they treat.
Also there's hundreds of thousands if not millions of Americans on them that are just fine. You're making the same dumb argument that some do about firearms.
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