Viagra (sildenafil) linked to fighting cancer.

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A new study published in Cancer Research found that sildenafil disrupts how cancer cells handle cholesterol, a fat tumors depend on to build the flexible membranes they need to invade new tissue. By trapping cholesterol inside a cellular recycling compartment, the drug may limit how much cholesterol cancer cells have to work with. Mouse experiments across breast, lung, and colon cancer models, conducted in female mice, showed reduced metastasis, while cell-line experiments showed reduced migration and viability. An analysis of health records from more than 40,000 male cancer patients found that men who had filled at least three sildenafil prescriptions in the six months before diagnosis and also used statins were associated with a 31% lower risk of death within five years, compared to those who used neither drug.

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