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re: New drug wipes out 94% of harmful cholesterol with A SINGLE DOSE in trials, lasts a year

Posted on 4/7/25 at 8:04 am to
Posted by tigeraddict
Baton Rouge
Member since Mar 2007
13505 posts
Posted on 4/7/25 at 8:04 am to
new sounds good..... but i'll wait years before thinking of taking and let other be the Guiney pigs......
Posted by tketaco
Sunnyside, Houston
Member since Jan 2010
21192 posts
Posted on 4/7/25 at 8:07 am to
Could it destroy plaque buildup in the veins? Or just preventative?
Posted by jeffsdad
Member since Mar 2007
23482 posts
Posted on 4/7/25 at 8:41 am to
Good question. I take repatha and the doc told me there is evidence that it does this but didn't know the extent. Repatha really changed my life. I was having stents about every 12 months and hadn't had one in 6 years now. Diet changes helped zero.
Posted by RobbBobb
Matt Flynn, BCS MVP
Member since Feb 2007
31269 posts
Posted on 4/7/25 at 10:42 am to
And it disappears in 3 . . . 2 . . 1
Posted by jizzle6609
Houston
Member since Jul 2009
15063 posts
Posted on 4/7/25 at 10:44 am to
quote:

side effects down the road will be?


Ever seen a pharma commercial?

It takes about 4 minutes for them to read the side effects normally.
Posted by lsu777
Lake Charles
Member since Jan 2004
35021 posts
Posted on 4/7/25 at 11:33 am to
quote:

Aren't we finding out now about severe intestinal blockage and hair loss from Semiglutides?


intestinal blockage has been a known side effect and only affects about 0.01% of people

hair loss is from people going on too severe of a deficit and not getting the vitamins they need, that is on them

glps are just naturally occurring hormones that we are taking more of but they have been out for over a decade, actually around 2 and studied for over 3 so we know most of the info on it




as far drug in the OP, sounds promising but i will wait and see on it. Alot of people are going to be skeptical which i understand but there are also about to be a lot of advances in pharma due to AI. huge leap forward in medicine and health in general

with all that said, the best thing 99% of people can do minimally is:

1) eat a protein based diet limiting processed foods
2) lift weights progressively 2-3x per week
3) get 8k steps per day
4) get some type of zone 2 cardio(think light jog) for 60min total a week
5) 6 hours sleep per night(8 is much much better)
6) get 30 min or so of sunlight daily


do those things consistently for a decade plus and you will be ahead of 99% of others then advances in medicine can prolong your life but you can put off taking them as long as possible.
Posted by ole man
Baton Rouge
Member since Nov 2007
15075 posts
Posted on 4/9/25 at 5:02 am to
You do remember covid don't you?
Posted by McLemore
Member since Dec 2003
33696 posts
Posted on 4/9/25 at 5:14 am to
quote:

They were able to get cholesterol into single digits, but just mild reduction in events,


Yep. Generally speaking, LDL is a necessary but insufficient condition for atherosclerotic events.

I’d like to see what Tom Daysrping says about the latest wonder drug. He is very balanced when it comes to interventions. And knows his shite better than anyone I’ve seen (not that I would know any different, but he has the credentials and wide credibility in the medical community. Can’t be accused of quackery).
Posted by ELVIS U
Member since Feb 2007
10959 posts
Posted on 4/9/25 at 5:34 am to
I'll stick to my Crestor
Posted by Locoguan0
Baton Rouge, LA
Member since Nov 2017
6322 posts
Posted on 4/9/25 at 5:38 am to
quote:

You have to clean up your diet and move more. There is no magic trick to it. Stop eating so much processed foods and sugar.


Some people are genetically predisposed to high cholesterol, so diet and exercise isn't the magic pill either.
Posted by Roaad
White Privilege Broker
Member since Aug 2006
79612 posts
Posted on 4/9/25 at 5:46 am to
quote:

I'll stick to my Crestor
It has what plants crave
Posted by McLemore
Member since Dec 2003
33696 posts
Posted on 4/9/25 at 6:08 am to
I just realized this isn’t a new trial. I’m sure there’s lots out there on it.

ETA:
Article from the other day. (I see, it targets Lp(a) and secondarily ApoB—sounds good on its face.)

LINK
This post was edited on 4/9/25 at 6:16 am
Posted by LSU alum wannabe
Katy, TX
Member since Jan 2004
27417 posts
Posted on 4/9/25 at 6:29 am to
Has to have some wild side effects.

That cholesterol has to go somewhere. Prepare your anus.
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